NCT: NCT00378612Sep 20, 2006Clinical Trial

ACROSS-Cypher Total Occlusion Study of Coronary Arteries 4 Trial

ClinicalTrials.gov
Sunil Rao

Abstract

ACROSS-Cypher® is a prospective, multi-center, open label, single arm study of the Cypher® sirolimus eluting coronary stent in native total coronary occlusion revascularization. The primary endpoint is binary angiographic restenosis at 6 months. The TOSCA-1 trial will be used as the historical control. The hypothesis is that compared with TOSCA-1 patients who were treated with the heparin-coated Palmaz Schatz stent, treatment with the Cypher® sirolimus eluting coronary stent will result in a >50% relative reduction in 6 month restenosis within the treated segment of the target vessel.

Associated Papers

Nov 15, 1996·The Journal of Clinical Investigation·M PoonA R Marks
May 1, 1994·Journal of the American College of Cardiology·J G WiedermannJ Weinberger
Oct 3, 2003·The New England Journal of Medicine·Jeffrey W MosesSIRIUS Investigators
Dec 21, 2004·Journal of the American College of Cardiology·Gerald S WernerHans R Figulla
Jun 3, 2004·Journal of the American College of Cardiology·Angela HoyePatrick W Serruys
Mar 1, 1976·Zdravookhranenie Rossiĭskoĭ Federatsii·E A LoginovaV S Korolev
Sep 14, 1999·Journal of the American College of Cardiology·M HöherA B Buchwald
Nov 30, 2000·Current Interventional Cardiology Reports· de Feyter PJB J Rensing
Jun 15, 1999·Journal of Cardiovascular Pharmacology·S E BurkeC D Wegner
Jan 16, 2004·The New England Journal of Medicine·Gregg W StoneTAXUS-IV Investigators
May 1, 1997·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·P J MohacsiP L Wijngaard
Jun 7, 2002·The New England Journal of Medicine·Marie-Claude MoriceRAVEL Study Group. Randomized Study with the Sirolimus-Coated Bx Velocity Balloon-Expandable Stent in the Treatment of Patie
Mar 1, 1976·Voenno-medit︠s︡inskiĭ zhurnal·G N Sedel'nikov
Jan 12, 2005·The American Journal of Cardiology·Sunao NakamuraDamras Tresukosol
Mar 4, 2000·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·T NoguchiH Nonogi
Nov 19, 2002·JAMA : the Journal of the American Medical Association·Steven R SteinhublCREDO Investigators. Clopidogrel for the Reduction of Events During Observation
Aug 24, 2000·Epidemiology·J M RobinsB Brumback
Jun 19, 1976·British Medical Journal·A D Farr

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