NCT: NCT01509937Jan 13, 2012Clinical Trial

Body Composition Monitor(BCM) Guided Fluid Management in Maintenance Hemodialysis (MHD) Patients
Li Zuo


It is hypothesized that bioimpedance spectroscope guided fluid management will help patient reach euvolemic status, and increase long term survival. Background: Bioimpedance analysis (BIA) was helpful in identifying hypervolemia. Observational data using BIA methods showed that hypervolemic patients on maintenance hemodialysis (MHD) suffered from high mortality risk. But it is not clear if BIA guided fluid management can improve MHD patients' survival. The objectives of the BOCOMO study are to evaluate the outcome of BIA guided fluid management comparing with standard care. Design: This is a multicenter, prospective, randomized, controlled trial. Setting and Participants: More than 1300 participants from 16 clinical sites will be included in the study. The enrollment period will last 6 months, and minimum length of follow-up will not less than 36 months. MHD patients aged more than 18 years but less than 80 years who had been on MHD for at least 3 months and considered suitable candidates will be invited to participate in the study. Participants will be randomized to BIA arm or control arm using 1:1 ratio. A portable whole body bioimpedance spectroscopy device (BCM-Fresenius Medical Care D GmbH) will be used for BIA measureme...Continue Reading

Associated Papers

Aug 26, 2004·Kidney International·Luana PillonGlenn M Chertow
Jan 30, 2007·Hemodialysis International·Bernard Charra
Jul 27, 2006·Physiological Measurement·Ulrich MoisslNigel J Fuller
Jan 7, 2000·Journal of the American College of Surgeons·A S JohnM D Kerstein
Nov 20, 2009·International Journal of Pediatric Obesity : IJPO : an Official Journal of the International Association for the Study of Obesity·Barbara S McClanahanLeslie P Schilling
Jan 10, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Volker WizemannDaniele Marcelli
Aug 8, 2002·Kidney International·Maarten A M JansenNECOSAD Study Group
Sep 25, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ezio MovilliGiovanni Cancarini
May 30, 2002·Croatian Medical Journal·Damir PuskarZdenko Sonicki
May 25, 2002·Kidney International·Paul W ChamneyVolker Wizemann
Sep 27, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Mehmet OzkahyaE J Dorhout Mees

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