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Telomere dysfunction in response to critical telomere shortening induces dna damage checkpoints that lead to cell cycle arrest and/or cell death.

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

GTPases, including small ras sub-families and large dynamin are regulators of intracellular trafficking. They are implicated in vesicular transport and important for the communication within cells. Discover the latest search on GTPases in intracellular trafficking here.

Rubella remains an important pathogen worldwide, with roughly 100,000 cases of congenital rubella syndrome estimated to occur every year. Here is the latest research.

Xeroderma Pigmentosum is an inherited condition cased by mutations in genes involved in DNA damage repair and characterized by extreme sensitivity to UV rays from sunlight. Here is the latest research.

Low grade gliomas in the brain form from oligodendrocytes and astrocytes and are the slowest-growing glioma in adults. Discover the latest research on these brain tumors here.

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

Find the latest research on epigenetics and twin studies here.

Examining the spatial arrangement of cell types in the retina and performing single cell analyses on these cell types will integrate information on the biology of these cells and development of disease. Discover the latest research pertaining to the Cell Atlas of the Neural Retina here.

An infected aneurysm is a bulge on a weakened blood vessel wall that has become infected. Treatment includes antibiotics and surgical intervention. Find the latest research on infected aneurysms here.

Ringworm is a fungal infection known for causing a ring-shaped rash on the skin. Discover the latest research on ringworm here.

Catatonia is a psychomotor symptom in which patients present with stupor, although catatonic excitement may also present at the other end of the spectrum. Catatonia has been historically associated with schizophrenia although it is also associated with other neuropsychiatric disorders. Find the latest research on catatonic schizophrenia here.

Meningococcal myelitis is characterized by inflammation and myelin damage to the meninges and spinal cord. Discover the latest research on meningococcal myelitis here.

Mutations in the LRRK2 gene are a risk-factor for developing Parkinson’s disease. However, LRRK2 has been shown to function as a central regulator of vesicular trafficking, infection, immunity, and inflammation. Here is the latest research on the role of this kinase on immunity during infection.

Membranoproliferative glomerulonephritis is type of Chronic glomerulonephritis characterized histologically by proliferation of mesangial cells, increase in the mesangial extracellular matrix, and a thickening of the glomerular capillary walls. Discover the latest research on membranoproliferative glomerulonephritis here.

Long noncoding rnas (lncrnas) are emerging as powerful regulators of cardiac development and disease. Here is the latest research.

Ancient DNA sequences are able to offer valuable insights into molecular evolutionary processes, but are notoriously difficult to analyze due to molecular damage and exogenous dna contamination. Discover the latest research on Ancient DNA here.

Telomeres protect our genetic data and are found at the end of chromosomes. When a cell divides, telomeres become shorter. This process has been associated with the development of cancer. Here is the latest research on telomeres in cancer.

Biodiversity refers to the variety and variability of life on Earth. Biodiversity is typically a measure of variation at the genetic, species, and ecosystem level.Discover the latest research on biodiversity data here.

Co-infections of a single host by multiple parasites is commonly observed. This feed focuses on parasitic co-infections and co-morbidities. Here is the latest research.

The novel CUT&Tag technique has the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Hutchinson-gilford progeria syndrome is a very rare premature aging disorder that affects children, clinically mimicking physiological aging at a young age. The disease incidence is estimated at 1 in 18 million. Discover the latest research on Hutchinson-gilford progeria syndrome here.

Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.

Nanopore sequencing is a third generation pproach used in the sequencing of biopolymers- specifically, polynucleotides in the form of DNA or RNA. Discover the latest research on nanopore sequencing.

CRISPR-Cas system enables the editing of genes to create or correct mutations. This technology is being investigated to combat malaria by targeting specific stretches of vector DNA and editing the genome at precise locations. Here is the latest research.

This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that affect virus-host interactions. Here is the latest research.

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Neural circuits are groups of interconnected neurons which carry out specific functions when activated. Imaging these neural circuits allows researches to further elucidate their mechanisms and functions. Follow this feed to stay up to date on brain imaging of neural circuits.

This feed focuses on the impact of smell and space perception, as well as mechanisms that underlie navigation behaviour in animals. Here is the latest research on olfactory navigation.

Multiple sclerosis (MS) is the most common chronic inflammatory disease of the central nervous system which is characterized by inflammatory demyelination and neurodegeneration. Here is the latest research on the influence of the human microbiome on this dymyelinating disorder.

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

The gut microbiota shares a symbiotic relationship with the human host. Dysbiosis is linked with several neurological pathologies including Parkinson’s disease (PD). Here is the latest research on the modulation of PD by the gut microbiota.

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Inflammatory breast cancer is a rare disease characterized by edema and redness of the breast. This is caused by metastatic breast cancer cells blocking lymphatic vessels. Discover the latest research on Inflammatory breast cancer here.

Single-cell analysis, including single-cell RNA sequencing, allows the discovery of new cell populations and expresssion patterns at single-cell resolution. When applied to neurogenetics, single-cell analysis can potentially uncover novel biological mechanisms underlying neurological disorders. Here is the latest research on Single-Cell Neurogenetics.

Circadian rhythms are essential for regulation of physiological and biochemical processes and its disruptions are associated with deleterious metabolic outcomes and diseases. Here is the latest research on circadian clocks and type 2 diabetes.

Central nervous system fungal infections are rare and typically occur in immunocompromised patients, such as those with HIV infection or transplant recipients. Discover the latest research on central nervous system fungal infections here.

IgA glomerulonephritis is a chronic form of glomerulonephritis characterized by deposits of predominantly Iimmunoglobin A in the mesangial area. Discover the latest research on IgA glomerulonephritis here.

Genetic screens can provide important information on gene function as well as the molecular events that underlie a biological process or pathway. Here is the latest research on genetic screens in bacteria.

Hebbian theory is a neuroscientific theory claiming that an increase in synaptic efficacy arises from a presynaptic cell's repeated and persistent stimulation of a postsynaptic cell. Find the latest research on Hebbian theory here.

Here is the latest research on neuroelectrophysiology and thalmo-cortical and neural dynamics in primates.

Sensorimotor circuits enable organisms, such as drosophila, to sense and respond to their environment. Here are the latest discoveries pertaining to sensorimotor circuits in drosophila.

This feed focuses on cellular respiration in bacteria, known as bacterial respiration. Discover the latest research here.

Nipah virus infection is an emerging zoonotic infection which presents with acute encephalitis and respiratory distress syndrome. Discover the latest research on Nipah Virus Infection here.

ADAR enzymes are responsible for a-to-i rna editing, an essential post-transcriptional rna modification contributing to transcriptome and proteome diversification.

Single-cell analysis, including single-cell RNA sequencing, allows the discovery of new cell populations and expresssion patterns at single-cell resolution. When applied to neurogenetics, single-cell analysis can potentially uncover novel biological mechanisms underlying neurological disorders. Here is the latest research on Single-Cell Neurogenetics.

This feed focuses on emerging cell and gene therapies, such as HIV vaccines, for treating patients living with HIV/AIDS. Discover the latest research here.

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Telomere dysfunction in response to critical telomere shortening induces dna damage checkpoints that lead to cell cycle arrest and/or cell death.

Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Examining genomics, transcriptomics, proteomics and metabolomics of the female reproductive system at the single cell level will help build a three-dimensional cellular map and insights into the health and disease of the female reproductive system. Discover the latest research on the human cell atlas of the female reproductive system here.

Fumarate Reductase is an enzyme that uses fumarate and quinol as substrates to generate succinate and quinone and has several biological functions, including a role in anaerobic respiration. Here is the latest research.

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Microphysiological systems (mps), also known as organs-on-a-chip, are a class of microfluidic platforms that recreate properties of tissue microenvironments.

Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) is a genome-wide technique used to map histone marks and protein binding (ie transcription factors) on chromatin. This can reveal insight into the regulation and dynamics of gene expression. Discover the latest research on ChIP-seq here.

Central nervous system (CNS) tumors have a unique tumor immune microenvironment, where immune cells can play a role in disease progression and resistance to therapy. Studying the immunogenetics of these cells can uncover mechanisms underlying their role in CNS tumors. Here is the latest research.

Nucleosome positioning influences transcription by regulating the chromatin accessibility to transcriptional machinery and chromatin remodelling proteins. Discover the latest research on Nucleosome Positioning here.

HIV infection increases the risk of non-communicable diseases common in the aged, including cardiovascular disease, neurocognitive decline, non-aids malignancies, osteoporosis, and frailty. Discover the latest research in AIDS malignancies.

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

Vitamin K-dependent carboxylases generate gamma-carboxyglutamic acids with malonate moieties by modifying glutamate residues in vitamin K-dependent proteins. This feed focuses on cellular mechanisms regulated by vitamin K-dependent carboxylases.

DNA replication is initiated as specific gene sequences, called origins, that function to start DNA replication. Pre-replication complexes are assembled at these origins during the G1 phase of the cell cycle. These sequences allow for targeted activation or deactivation of replication. Discover the latest research on DNA replication origins here.

This feed focuses on subcellular and translation regulation of RNA in Axons and how this influences Axonal Functions. Discover the latest research here.

This feed focuses on genetic aspects of neurodegeneration and aging, with emphasis on the role of protein aggregates in neurodegenerative diseases including Alzhiemer’s. Here is the latest research.

Mutations, single nucleotide variants and large genomic rearrangements, in non-coding regions of the genome can have severe consequences such as disruption of transcription factor binding sites and functions of non-coding RNAs and can impact tumor development and progression. Here is the latest research.

Cytokinesis is the highly regulated process that physically separates daughter and mother cells in late mitosis. The mitotic-exit network (MEN), the signalling pathway that drives mitotic exit, directly regulates cytokinesis. Discover the latest research on mitotic-exit networks with cytokinesis here.

Genetically engineered mouse models provide researchers with a better understanding of cancer genes and tumor biomarkers, the mechanisms underlying tumor initiation and metastasis, and novel therapeutic strategies in cancer. Discover the latest research on mouse models in cancer here.

Hereditary breast and ovarian cancer due to mutations in the brca1 and brca2 genes is the most common cause of hereditary forms of both breast and ovarian cancer. Here are the latest discoveries pertaining to these cancers.

Oxygen tension is determined by the balance between net oxygen entering the system and the consumption of oxygen by cells, which can be affected by cell density and type. For instance, hepatocytes consume higher levels of oxygen compared to endothelial cells. Here is the latest research on oxygen tension in liver models.

The effect of cannabis on cognitive functioning is being explored for short and long-term effects. Recent studies have shown conflicting results, with some showing no significant effects and others showing neuropsychological impairment. Discover the latest research on cannabis and cognition here.

Retinitis Pigmentosa is a hereditary, progressive degeneration of the retina due to death of rod photoreceptors initially and subsequent death of cone photoreceptors. It is characterized by deposition of pigment in the retina.Discover the latest research on retinitis pigmentosa here.

Cystic fibrosis is an autosomal recessive disease, which is the result of a genetic defect in the cystic fibrosis transmembrane conductance regulator (cftr) gene. Here is the latest research on this disease

Prader-Willi Syndrome (PWS) is a genetic disorder caused due to the absent expression of a set of genes on chromosome 15. Here is the latest research on this complex multisystem disorder.

Castleman Disease is a rare lymphoproliferative disorder that can progress into lymphoma. Discover the latest research on Castleman Disease here.

Li-Fraumeni Syndrome is a rare autosomal dominant syndrome caused by mutations in the tumor suppressor TP53 and characterized by mesenchymal and epithelial neoplasms and several sites. Here is the latest research.

Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research.

Huntington disease is a hereditary neurodegenerative disease characterized by poor coordination and involuntary body movements. Discover the latest research on Huntington disease here.

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Hodgkin disease or Hodgkin's lymphoma is a type of lymphoma that affects the lymph system. Here is the latest research on Hodgkin disease.

22q11.2 deletion syndrome, also known as DiGeorge syndrome, is a congenital disorder caused as a result of a partial deletion of chromosome 22. Here is the latest research.

Charcot-Marie-Tooth (CMT) disease is a hereditary motor and sensory neuropathy characterized by loss of muscle and touch sensation. Discover the latest research on CMT here.

Progressive Supranuclear Palsy (PSP) is a rare neurodegenerative disorder that affects movement, gait, balance, and speech. Discover the latest research on PSP here.

Neurofibromatosis 1 (NF1), also known as von Recklinghausen disease, is an autosomal dominant condition caused by mutations in the NF1 gene. Here is the latest research.

Marfan syndrome is an autosomal dominant disorder of connective tissue with abnormal features in the heart, the eye, and the skeleton. It is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue. Discover the latest research on Marfan syndrome here.

Creutzfeldt-Jakob Disease is a fatal neurodegenerative disease caused due to aggregation and accumulation of misfolded prion proteins. Here are the latest discoveries pertaining to this disease.

Fragile X syndrome is caused by an expanded CGG repeat (> 200 repeats) in the 5' untranslated portion of the fragile mental retardation 1 gene (FMR1) within the X chromosome, leading to deficiency of fragile X mental retardation protein (FMRP). It is cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. Intellectual disability occurs in nearly all males and roughly 50% of females with the full mutation. Discover the latest research on Fragile X syndrome here.

Glioblastoma Multiforme (GBM) is a tumor that develops from astrocytes and oligodendrocytes. Here is the latest research on mechanisms that underlie GBM and associated therapeutic approaches.

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS here.

Rett syndrome is a severe neurological disorder caused by mutations in the X-linked gene methyl-CpG-binding protein 2. Discover the latest research on Rett syndrome here.

Chromatin remodeling is essential for regulation of gene expression, DNA replication, as well as DNA repair. Here is the latest research on chromatin remodeling complexes and mechanisms underlying chromatin remodeling.

Tissue engineering is an interdisciplinary field that aims to create, repair, and/or replace tissues and organs by using biomaterial scaffolds, growth factors, stem cells, and genetic engineering. Discover the latest preprints on tissue engineering here.

Cancer immunotherapy is an important field of research that is looking at controlling cancer and tumor growth by activating the individuals own immune system. Recent studies have utilized chimeric antigen receptor t-cell therapy, immune checkpoint inhibitors and neoantigen vaccines. Discover the latest preprints on cancer immunotherapy here.

MAPK pathway is a complex signaling pathway that regulates transcription, translation, cell cycle, and proliferation. Targeting this pathway has long been considered a promising strategy for cancer therapy. Here is the latest research on this pathway.

Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here are the latest preprints on the use of CRISPR-Cas system in gene editing.

The Human Tumor Atlas is a collaborative project that uses detailed maps of a variety of cancers to investigate cancer development, metastasis, and treatments. Discover the latest preprints from the Human Tumor Atlas here.

Cancer genomics employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest preprints here.

This feed focuses on Type 2 Diabetes, a disease where the body doesn’t produce or respond to insulin anymore, leading to abnormal glucose levels in the blood.

Computation neuroscience employs models, statistics, simulations, and theoretical analyses to understand mechanisms that govern neural functions. Here are the latest preprints in this domain.

Parkinson’s disease is a progressive neurodegenerative disorder that affects movement. This feed focuses on genetic screening approaches and genetic predispositions in Parkinson’s disease.

Human immunodeficiency virus (HIV) is a retroviral infection that can lead to acquired immunodeficiency syndrome (AIDS). HIV can be effectively controlled through antiviral drugs to prevent progression to AIDS. Discover the latest preprints on HIV here.

Cognitive neuroscience is the study of biological processes that underlie cognition and addresses the role of neural circuits in regulating cognitive activities. Here are the latest preprints on cognitive neuroscience.

Asthma is a condition in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath. Discover the latest preprints here.

Genes and microglia are associated with the risk of developing and the progression of conditions such as Alzheimer's Disease (AD). Here are the latest preprints pertaining to this disease.

Ubiquitin is a small regulatory protein that is attached to proteins as a post-translational modification in a process known as ubiquitination to regulate protein turnover, location, or activity. Here is the latest research on the ubiquitin system.

Chaperones are proteins that play an essential role in protein folding, stability, assembly, and degradation. Their depletion or dysfunction has been implicated in protein folding disorders. Here are the latest preprints on chaperone proteins.

Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level. Hypoxia may be classified as either generalized, affecting the whole body, or local, affecting a region of the body. Discover the latest preprints here.

The human microbiome refers to the collection of genomes of all the microorganisms inside the human body and on the surface. Discover the latest preprints on the human microbiome here.

G-protein-coupled receptors (GPCRs), the largest family of integral membrane proteins, participate in the regulation of many physiological functions and are the targets of approximately 30% of currently marketed drugs. Here are the latest preprints on GPCRs.

Protein function prediction methods are techniques that bioinformatics researchers use to assign biological or biochemical roles to proteins. Discover the latest research on protein function prediction here.

Fluorescence in situ hybridization (FISH) is one of the major techniques used to detect of chromosomal aberrations. Here is the latest research.

Genome surgery using CRISPR genomic techniques offer the potential to correct disease-causing mutations in many neuronal disorders. Here are the latest discoveries pertaining to genome surgery and neuronal disorders.

Non-coding RNAs (ncRNAs) are RNA molecules that do not code for protein, but can have functional roles in regulating gene expression at the transcriptional and post-transcriptional level. Discover the latest research on the role of ncRNAs in Health and Disease.

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression through inhibition of protein translation or by degradation of specific transcripts. miRNAs can regulate cardiovascular health, and be potential biomarkers or targets in cardiovascular disease. Discover the latest research on miRNAs in Cardiovascular Biology here.

Nanoparticles enable the delivery of substances, including nucleic acids and chemotherapeutic drugs, to a targeted region while sparing healthy tissues, thus overcoming adverse systemic effects of gene therapy or drug delivery. Here is the latest research on nanoparticle delivery.

Adult stem cells have been extensively studied for tissue repair and regeneration. Discover the latest research on stem cell tissue repair here.

Development of gene editing techniques, including CRISPR and TALENs, has relied on mechanisms that underlie DNA repair and genome stability pathways. This feed focuses on the role of DNA repair mechanisms in gene editing and genetic engineering.

Cancer immunotherapy is an important field of research that is looking at controlling cancer and tumor growth by activating the individuals own immune system. Recent studies have utilized chimeric antigen receptor t-cell therapy, immune checkpoint inhibitors and neoantigen vaccines. Discover the latest research on cancer immunotherapy here.

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

Differences in genetic backgrounds pose a limitation to studying and inferring genetic mechanisms of diseases. These limitations can be overcome using induced pluripotent stem cell-derived isogenic models of diseases. Here is the latest research.

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

This feed focuses on novel advances in medical devices used to manage type I diabetes, such as an artificial pancreas and insulin pumps.

Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here is the latest research on the use of CRISPR-Cas system in gene editing.

Circulating free DNA (cfDNA) are degraded DNA fragments released to the blood plasma. cfDNA has been shown to be a useful biomarker for a multitude of ailments other than cancer and fetal medicine. Here is the latest research on Circulating free DNA (cfDNA) sequencing.

Mammalian cells & synthetic biology describes the recent advancements in mammalian synthetic biology where new technologies and tools are developed to programm and probe mammalian cell behaviours that can lead to potential therapeutic applications. Discover the latest research on mammalian cells and synthetic biology here.

Metabolomics refers to the large-scale study of profiling all metabolites in biological systems in a non-targeted manner. Here is the latest research.

Recently, cerebral organoids derived from induced pluripotent stem (ips) cells have illuminated early developmental events altered by disease processes, and may be a promising avenue for future therapies in neurodegenerative disorders. Here is the latest research on Organoids & Neurodegeneration.

Adeno-associated virus (AAV)-based gene therapy is a biological vector that is being researched to be used as a potential therapeutic option. This gene therapy is designed to insert fragments of DNA into targeted cells to help treat diseases, such as hemophilia a. Discover the latest research on AAV-based gene therapy here.

The London School of Hygiene and Tropical Medicine involves cross-disciplinary research groups including laboratory, clinical, population and social sciences, all working to address major public and global health challenges. Their research contributes to health policy and practice in the UK and around the world. Follow this feed to stay up to date on work published by this institute.

The Chan-Zuckerberg Biohub aims to support the fundamental research and develop the technologies that will enable physicians to cure, prevent, or manage all diseases in our childrens' lifetimes. The CZ Biohub brings together researchers from UC Berkeley, Stanford, and UCSF. Find the latest research from the CZ Biohub researcher network here.

Find the latest research from the Stanford Medicine Department of Genetics here.

European Bioinformatics Institute focuses both on data resource development and investigator-driven research in the field of bioinformatics. Follow this feed to stay up to date on research by this institute.

The Neurodegeneration Challenge Network aims to provide funding for and to bring together researchers studying neurodegenerative diseases. Find the latest research from the NDCN grantees here.

Institute for Stem Cell Biology and Regenerative Medicine, at Stanford University was established in 2002 with the goal of discovering how the stem cells are created regulated, how they differentiate, and ultimately translate this knowledge into new medical therapies. Follow this feed to stay up to date on research published by the members of this institute.

The Eli and Edythe L. Broad Institute of MIT and Harvard was launched to gain a better understanding of human health and disease through genomics. Find the latest research from the Broad Institute here.

The International Cancer Genome Consortium (ICGC) was founded with the goal of mapping the genome of 25,000 primary untreated cancers. The ICGC has also pushed for the global sharing of genomic data to facilitate cancer research. Find the latest research from the ICGC here.

The National Human Genome Research Institute (NHGRI) supports research focusing on genomics related human health and disease. To stay updated on research published by NHGRI follow this feed.

Institut Curie - Centre de Recherche covers multiple areas of research: the biology of radiations, cell signaling and Cancer, second Development biology, Cancer, Genetics and Epigenetics, third integrative tumor biology, immunology and environment, and fourth multiscale Physics-Biology-Chemistry and Cancer. Follow this feed to stay updated on research from this group.

The aim of the Human Cell Atlas is to build reference maps of all human cells in order to enhance our understanding of health and disease. Follow the latest research from the Human Cell Atlas Consortium here.

The International Cancer Genomics Consortium (ICGC) was established to investigate the genomic changes present in many forms of cancer. Follow this feed to stay up to date on research from this institute.

The KEMRI-Wellcome Institute - Researcher Network was formed through a partnership between Kenya Medical Research Institute formed a partnership with the Welcome Trust and the University of Oxford. Their major research themes are Clinical Research, Population health, Health Systems, Genomics and infectious disease transmission and Vaccines. Follow this feed to stay up to date on work published by this institute.

National Institute of Allergy and Infectious Diseases (NIAID) goal is to perform leading research to understand, treat, and prevent infectious, immunologic, and allergic diseases. Follow this feed to stay updated on research from this group.

The Trans-NIH Pediatric Research Consortium coordinates the pediatric research programs funded by NIH to promote collaboration, explore gaps and opportunities in the NIH pediatric research portfolio. Follow this feed to stay up to date on publications from this institute.

The Developmental Human Cell Atlas Network aims to profile the various cell types and differentiation programs involved in development. Find the latest research from the Developmental Human Cell Atlas Network here.

The Allen Institute for Brain Science Network is a not-for-profit biomedical research organization that provides open access to multiple neuroscience tools and resources. Find the latest research from tjr Allen Institute for Brain Science Network here.

The University Department of Paediatrics is part of the School of Clinical Medicine, at the University of Cambridge, and is located on the Addenbrooke’s Hospital site. The Department of Paediatrics is involved in teaching, research and clinical practice and is an internationally recognised centre for research in child health and development. Here is the latest research on researchers in the Department of Paediatrics at the University of Cambridge.

Yale Stem Cell Center (YSCC) focuses on understanding how stem cells function, what causes them to multiply and how they can be induced to differentiate into different lineages. Follow this feed to stay up to date on work published by this group of researchers.

Epigenetic changes, such as changes in histone modification patterns and noncoding RNA expression levels, have a strong influence on the aging process. Discover new insights into the role of epigenetics in aging in this feed.

Induced pluripotent stem cells (iPSCs) may be obtained by direct reprogramming of different somatic cells to a pluripotent state by forced expression of a handful of transcription factors, These cells have similar properties to those of embryonic stem cells (escs) but bypass the ethical concerns of embryo destruction and can be exploited for both research and clinical applications.Discover the latest research on iPSC here.

Immunometabolism involves not only the way metabolites are digested by the immune system, but the way in which they can alter the pathway of the immune system. These responses occur in day-to-day healthy cell functioning, but can result in diseases, such as autoimmune disorders. Discover the latest research on cellular immunometabolism here.

The Hippo pathway regulates diverse cellular phenotypes such as organ size, angiogenesis, tissue regeneration and self-renewal. YAP and TAZ important transcriptional coactivators downstream of hippo signaling. Discover the latest research on Hippo Pathway-YAP/TAZ here.

Investigating human cellular proteins through a combination of highly multiplexed imaging and proteomic analyses can help characterize all human cells at the proteomic level. Discover the latest research on deep visual proteomics here.

Adult stem cells have been extensively studied for tissue repair and regeneration. Discover the latest research on stem cell tissue repair here.

Migration of cancer cells into surrounding tissue and the vasculature is an initial step in tumor metastasis. Discover the latest research on cell migration in cancer and metastasis here.

Single-Cell Analysis is the study of genomics, transcriptomics, proteomics and metabolomics at the single cell level.[1][2] Due to the heterogeneity seen in both eukaryotic and prokaryotic cell populations, analyzing a single cell makes it possible to discover mechanisms not seen when studying a bulk population of cells. Here is the latest research on Single-Cell Analysis.

Lipid metabolism refers to the synthesis and degradation of lipids in cells and is a complex process essential for fat storage and construction of cellular membranes. Discover the latest research on lipid and membrane metabolism here.

A dynamic cytoskeleton is critical for the generation of cell polarity. This feed focuses on cell polarity and the cytoskeleton, including actin and microtubular cytoskeletal organization.

The nuclear pore is a large complex of proteins that allow macromolecules to cross from the nucleus to the cytoplasm and vice versa. Discover the latest research on the structure and function of the nuclear pore here.

Circadian rhythms are natural, internal processes that regulate the sleep-wake cycle. Chronic disruptions in circadian rhythms have been associated with the development of a variety of diseases including cancer. Here is the latest research on circadian rhythms and cancer.

Contractile forces generated by the actin-myosin cytoskeleton are critical for morphogenesis, but the cellular and molecular mechanisms of contraction have been elusive for many cell shape changes and movements. Here is the latest research on the roles of actin and myosin in cell movement.

Organoids are 3D organ-like structures that can be derived from patient tumor cells to model disease. Discover the latest research here.

Organoids are three-dimensional structures derived from adult or embryonic stem cells, tissues, or tumors, that enable the mimicry of in vivo architecture in tissue culture. Here is the latest research on organoids.

Neuronal plasticity is the brain’s ability to change its structure and function in response to internal or external factors. Here is the latest research on mechanisms that influence this process.

Mammalian cells & synthetic biology describes the recent advancements in mammalian synthetic biology where new technologies and tools are developed to programm and probe mammalian cell behaviours that can lead to potential therapeutic applications. Discover the latest research on mammalian cells and synthetic biology here.

Autophagy is a lysosomal pathway that involves degradation of proteins and functions in normal growth and pathological conditions, through a series of complex networks. The catabolic process involves delivery of proteins and organelles to the lysosome. Here is the latest research on autophagy networks.

Ribosomes synthesize and, sometimes in association with chaperone proteins, fold amino acid polypeptides into active 3D proteins. Here is the latest research on ribosomes and protein folding.

Discover the latest diabetes research published by the journals from the American Diabetes Association.

Discover the latest infectious disease research in this collection of the top infectious disease journals.

Discover the latest respiratory research published by the journals from the American Thoracic Society.

Discover the latest general biology research in this collection of the top biology journals.

Discover the latest research from the prestigious journals: Nature, Cell, and Science.

The American Society for Biochemistry and Molecular Biology (ASBMB) includes the Journal of Biological Chemistry, Molecular & Cellular Proteomics, and the Journal of Lipid Research. Discover the latest research from ASBMB here.

Discover the latest genomics research in this collection of the top open access genomics journals.

Cell is a scientific journal publishing research across a broad range of disciplines within the life sciences field. Discover the latest research from Cell here.

Discover the latest cardiology research in this collection of the top cardiology journals.

Discover the latest reviews in immunology research in this collection of the top immunology review journals.

Nature is the world's leading multidisciplinary science journal. Discover the latest research from Nature here.

Science Magazine is a peer-reviewed academic journal of the American Association for the Advancement of Science. Find the latest research from Science here.

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

The Proceedings of the National Academy of Sciences (PNAS) is a peer-reviewed multidisciplinary scientific journal. Here are the latest research papers from PNAS.

The Journal of the American Medical Association (JAMA) is a peer-reviewed medical journal published by the American Medical Association. Here are the latest research papers from JAMA.

The New England Journal of Medicine (NEJM) is a medical journal published by the Massachusetts Medical Society. Discover the latest research from NEJM here.

eLife is a peer-reviewed open access scientific journal for the biomedical and life sciences. Find the latest research from eLife here.

Discover the latest reviews in cancer research in this collection of the top cancer review journals.

Discover the latest neuroscienceresearch in this collection of the top neuroscience journals.

Tau vaccination and administration of anti-tau antibodies can prevent pathology and cognitive impairment in transgenic mouse models of tauopathy, suggesting that therapies which increase anti-tau antibodies might slow the development and/or progression of tauopathies including Alzheimer's disease. Here is the latest research.

Olivopontocerebellar atrophy (OPCA) refers to neurodegeneration of the inferior olivary nucleus, pons, and the cerebellum, and is characterized by cerebellar ataxia and other neurological problems. Here is the latest research.

Leigh syndrome, caused by a dysfunction in mitochondrial energy metabolism, is an inherited, heterogeneous, and progressive neurodegenerative disorder of infancy and childhood. Discover the latest research on Leigh syndrome here.

This feed focuses on the C9orf72 protein and its possible role in lysosome function and implication in frontotemporal dementia and amyotrophic lateral sclerosis

Globoid cell leukodystrophy (GLD) or Krabbe disease is a neurodegenerative disorder caused by the deficiency of the lysosomal enzyme galactocerebrosidase (GALC). Discover the latest research on globoid cell leukodystrophy here.

TAR DNA binding protein (TDP43) is a DNA and RNA binding protein that is implicated in several neurodegenerative disorders known as “TDP43 proteinopathies" including Alzheimer's disease, amyotrophic lateral sclerosis and frontotemporal lobe dementia. Here is the latest research.

Alzheimer's disease is a chronic neurodegenerative disease which can be studied using various experimental systems. This feed focuses on animal models used for Alzheimer's disease research.

Alzheimer's disease (AD) is a chronic neurodegenerative disease associated with accumulation of amyloid plaques, which are comprised of amyloid beta. Here is the latest research in this field.

Fatal familial insomnia is a familial prion disease linked to a mutation of the prion protein gene. Here is the latest research on this rare genetic degenerative brain disorder.

Tau toxicity has been implicated in the emergence of synaptic dysfunction in Alzheimer's disease. Here is the latest research on Tau Toxicity in the Synapses.

Alpha-synuclein is an integral component of Lewy bodies which are comprised of protein clumps and are a pathological hallmark of Parkinson’s disease. Here is the latest research.

Understanding genetic influences on neuronal aging can guide potential therapies to slow age-related cognitive decline and other age-related neurological disorders. Discover the latest research on neurogenetics in aging here.

ALS shares with a considerable proportion of FTD cases the same neuropathological substrate, namely, inclusions of abnormally phosphorylated protein tdp-43 (ptdp-43). Here are the latest discoveries pertaining to ptdp-43 and these diseases.

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Distinct prion strains are associated with different prion protein conformations and glycosylation patterns and associate with disease progression and severity. Here is the latest research on strain diversity and neurotoxicity in prion diseases.

Alzheimer's disease is a chronic neurodegenerative disease. This feed focuses on the underlying role of Tau proteins and TAR DNA-binding protein 43, as well as other genetic factors, in Alzheimer's.

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion proteins, as an important biomarker of prion disease, are responsible for the transmissible spongiform encephalopathies. Here is the latest research investigating biomarkers in prion diseases.

Gut microbiota has been implicated in neurodevelopment, neuroinflammatory responses, and neurological disorders. Here is the latest research on the role of gut microbiota in movement disorders.

Alzheimer's disease (AD) is a chronic neurodegenerative disease. Here is the latest research on neuroimaging modalities, including magnetic resonance imaging and positron emission tomography, in AD.

Alzheimer's disease is a chronic neurodegenerative disease. This feed focuses on early markers, as well as environmental, pharmacological, and drug-response biomarkers associated with this disease.

Frontotemporal lobar degeneration or frontotemporal dementia refers to a group of uncommon disorders that occur as a result of progressive nerve cell loss in the frontal and temporal lobes of the brain. Here is the latest research.

Amyloid beta is neurotoxic and a major component of plaques in Alzheimer’s disease. Accumulation induces neurotoxic effects including oxidative damage and mitochondrial dysfunction. Breakdown of amyloid is important to prevent the development of Alzheimer’s disease. Here is the latest research on amyloid beta deposition and degradation.

α-Synuclein is an integral component of Lewy bodies which are comprised of protein clumps and are a pathological hallmark of Parkinson’s disease. Here is the latest research on α-Synuclein structure and function.

RNA regulation involves several mechanisms that are used by cells to decreases or increase the production of RNA. Issues with RNA regulation are associated with Alzheimer's Disease (AD). Here are the latest discoveries pertaining to RNA regulation and this disease.

α-Synuclein is an integral component of Lewy bodies which are comprised of protein clumps and are a pathological hallmark of Parkinson’s disease. Here is the latest research on α-Synuclein structure and function.

The relationship between astrocytes and amyloid has been suggested in some neurological diseases such as Alzheimer’s disease. Neuronal damage stimulates the activation of reactive astrocytes, which may the source of amyloid that forms in Alzheimer’s. Here is the latest research on astrocytes and amyloid.

Tau and alpha-synuclein are proteins that form aggregates which characterize various neurodegenerative disorders including Parkinson’s disease. This feed focuses on the reaction of T lymphocytes in response to tau and alpha-synuclein.

Tau Aggregation is an important characteristic in some neurodegenerative disorders, including Alzheimer’s Disease. Discover the latest research using genomics to understand Tau Aggregation.

Protein misfolding is the primary cause of several neurodegenerative disease, including Alzheimer’s and Parkinson’s disease. Here is the latest research.

Tau mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17) are associated with changes in alternative RNA splicing. Here is the latest research on RNA & Tau in Frontotemporal Dementia.

Alzheimer's disease is a chronic neurodegenerative disease. Discover genetic and epigenetic aspects of Alzheimer’s disease, including genetic markers and genomic structural variations here.

Alpha-synucleins are small proteins that are believed to restrict the mobility of synpatic vesicles and inhibit neurotransmitter release. Aggregation of these proteins have been linked to several types of neurodegenerative diseases including dementia with Lewy bodies and Parkinson's disease. Here is the latest research on α-synuclein aggregation.