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This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

The motor cortex is associated with planning, control, and execution of voluntary movements. This feed focuses on bi-directional communication pathways between an external device and the motor cortex.

When demyelination occurs an inflammatory response is activated. Accumulation of excess myelin debris triggers cholesterol crystal formation, and cholesterol deposits in the CNS can overwhelm phagocytes, resulting in impaired tissue regeneration. Here is the latest research on cholesterol synthesis in inflammation and remyelination.

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Early myoclonic encephalopathy is an epileptic syndrome typically diagnosed by three months of age. It is characterized by frequent seizures and severe early encephalopathy and has a severely reduced life expectancy. Causes can include metabolic abnormalities or genetic mutations. Find the latest research on early myoclonic encephalopathy here.

Tendons are rich in the extracellular matrix and are abundant throughout the body providing essential roles including structure and mobility. The transcriptome of tendons is being compiled to understand the micro-anatomical functioning of tendons. Discover the latest research pertaining to the Tendon Seed Network here.

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

DDX3X syndrome is caused by a spontaneous mutation at conception that primarily affects females due to its location on the X-chromosome. DDX3X syndrome has been linked to intellectual disabilities, seizures, autism, low muscle tone, brain abnormalities, and slower physical developments. Here is the latest research.

Prion diseases are fatal neurodegenerative and infectious disorders characterized by structural transition of the host-encoded cellular prion protein into the aberrantly folded pathologic isoform of the protein. Here is the latest research on diagnostic strategies for prion diseases.

Opsonization of apoptotic cells facilitates recognition by phagocytes for the rapid clearance of potentially inflammatory cellular material. Here is the latest research.

This feed focuses on the role of the mitochondria and cholesterol on neurodevelopmental disorders (ND).

Like other coronaviruses, SARS-CoV-2 is evolving. The genomic diversity of SARS-CoV-2 strains in different countries is consistent with multiple introductions of the virus to different locations, seeding local transmission events. The papers in this feed report latest research into genetic variation and phylogeny of this highly successful virus.

Cytokinesis is the highly regulated process that physically separates daughter and mother cells in late mitosis. The mitotic-exit network (MEN), the signalling pathway that drives mitotic exit, directly regulates cytokinesis. Discover the latest research on mitotic-exit networks with cytokinesis here.

Cardiac organoids are 3D organ-like structures that can be derived from patients with cardiovascular diseases and are important disease models for drug discovery. Discover the latest research on Cardiac Organoids here.

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

microRNAs (miRNAs) are key regulatory RNAs that control gene expression in various biological processes and human diseases such as Spinocerebellar Ataxia. Here are the latest discoveries pertaining to miRNAs and this disease.

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

This feed focuses on emerging cell and gene therapies, such as HIV vaccines, for treating patients living with HIV/AIDS. Discover the latest research here.

Prion diseases are fatal neurodegenerative and infectious disorders characterized by structural transition of the host-encoded cellular prion protein into the aberrantly folded pathologic isoform of the protein. Here is the latest research on diagnostic strategies for prion diseases.

GRIP1 is a glutamate receptor interacting protein 1 and myeloid cells consists of granulocytes and monocytes, before they have differentiated and are derived from hematopoietic stem cells. The interaction between GRIP1 and myeloid cells in inflammation is in the early stages. Here is the latest research on GRIP1 and myeloid cells in inflammation.

Fumarate Reductase is an enzyme that uses fumarate and quinol as substrates to generate succinate and quinone and has several biological functions, including a role in anaerobic respiration. Here is the latest research.

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

Vitamin K-dependent carboxylases generate gamma-carboxyglutamic acids with malonate moieties by modifying glutamate residues in vitamin K-dependent proteins. This feed focuses on cellular mechanisms regulated by vitamin K-dependent carboxylases.

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Mutations, single nucleotide variants and large genomic rearrangements, in non-coding regions of the genome can have severe consequences such as disruption of transcription factor binding sites and functions of non-coding RNAs and can impact tumor development and progression. Here is the latest research.

Hereditary breast and ovarian cancer due to mutations in the brca1 and brca2 genes is the most common cause of hereditary forms of both breast and ovarian cancer. Here are the latest discoveries pertaining to these cancers.

The cervix contains two types of cells and when cancer arises from squamous cells within the cervix it is cervical squamous cell carcinoma. The endocervix is located just above the body of the cervix and contains glandular cells. When cancer begins here it is called endocervical adenocarcinoma. Here is the latest research on these two types of cancers.

AFM in situ DNA describes in situ analysis (or study) of DNA using atomic force microscopy. Discover the latest research on AFM in situ DNA here.

Examining genomics, transcriptomics, proteomics and metabolomics of the female reproductive system at the single cell level will help build a three-dimensional cellular map and insights into the health and disease of the female reproductive system. Discover the latest research on the cell atlas of the female reproductive system here.

Oxygen tension is determined by the balance between net oxygen entering the system and the consumption of oxygen by cells, which can be affected by cell density and type. For instance, hepatocytes consume higher levels of oxygen compared to endothelial cells. Here is the latest research on oxygen tension in liver models.

Human and animal data suggest that the hippocampus plays many roles in regulating food intake. Discover the latest research on hippocampus and feeding here.

A SARS-CoV-2 vaccine would be a very powerful tool to slow down the COVID-19 pandemic. Well over a hundred vaccine candidates are in development, with some already being tested for safety and efficacy, or in phase I clinical trials. This feed follows the latest studies on vaccine design and development.

Although children rarely develop severe COVID-19 symptoms, a number of pediatric cases have been reported that associate SARS-CoV-2 infection with the development of a proinflammatory syndrome resembling Kawasaki disease and toxic shock syndrome. Ongoing research into this Multisystem Inflammatory Syndrome (MIS-C) is highlighted in this feed.

The entry of coronaviruses into susceptible host cells is mediated by the viral S (Spike) glycoprotein. This feed covers latest findings about this complex process and the ongoing research efforts into finding therapeutics that can target the viral Spike protein and hence disrupt virus-cell fusion.

Understanding the innate and acquired immune response to SARS-CoV-2 is essential for development of COVID-19 therapeutic treatment and design of prophylactic vaccines. This feed surfaces immunological studies, including studies into the cytokine storm that has been observed in severely ill patients.

COVID-19 patients frequently have neurological symptoms, which are probably caused by the virus invading the central nervous system. Symptoms range from a loss of smell and taste to serious complications such as encephalitis, many of which are associated with poor prognosis. This feed follows the latest developments and research into the neurological complications associated with COVID-19.

The provision of Personal Protective Equipment for hospital staff and other workers providing essential services has been a key challenge in the early stages of the COVID-19 pandemic. Research into the protection offered by PPE, as well as best-practice guidelines for PPE use, is covered in this feed.

This feed represents a collection of systematic literature reviews available for COVID-19 and coronaviruses. These reviews use systematic methods to collect and critically assess secondary data available for a specific research question, providing a synthesis of qualitative or quantitative findings.

COVID-19 patients typically present with high fever and a persistent cough. This feed focuses on clinical diagnosis, including RT-PCR testing for the presence of SARS-CoV-2 and radiographic assessment of lungs.

A growing number of complications associated with COVID-19 has been identified. This feed focuses primarily on cardiovascular and respiratory manifestations in severely ill patients.

The SARS-CoV-2 virus enters the human host cell via the receptor ACE2 and uses the serine protease TMPRSS2 for S protein priming. The ACE2 usage has been shown to be crucial for transmissibility of other coronaviruses. Much research into the COVID-19 pandemic focuses on understanding the complex process of virus entry.

Convalescent plasma therapy, where passive polyclonal antibody obtained from recovered patients are used to provide immediate immunity, has been tested in respiratory infections such as the 2009-2010 H1N1 influenza virus pandemic and the 2003 SARS-CoV-1 epidemic. This feed follows ongoing research efforts and clinical trials exploring covalescent plasma therapy as a potential treatment strategy for COVID-19.

Various research strategies are being deployed to control the COVID-19 pandemic, including a search for a vaccine. This feed covers primarily the ongoing research efforts that are focused on repurposing existing antiviral drugs and finding novel therapeutic treatments.

Growing evidence shows that COVID-19 can result in serious complications affecting the cardiovascular system, including dysrhythmias, myocarditis, acute myocardial infarction, and heart failure. This feed follows studies investigating the effects of SARS-CoV-2 infection on the heart.

Epidemiological studies play a crucial role in understanding and managing the progression of COVID-19. Research followed in this feed includes studies of transmission dynamics and the change of the basic reproductive number (R) as new pubic health measures take effect.

The research highlighted in this feed investigates the immunopathology seen in severely ill COVID-19 patients, which often resembles the cytokine storm syndrome: uncontrolled immune activation generates excessive release of cytokines, resulting in hyperinflammation and multi-organ disease.

Models that predict the course of the COVID-19 epidemic have been crucial in developing public health policies and continue to be used to plan effective control strategies. This feed surfaces papers reporting new models and modeling methods applied to COVID-19 data.

While most COVID-19 infections cause only mild to moderate symptoms, severely affected patients, such as those presenting with pneumonia, ARDS or septic shock, require hospitalization. This feed focuses on clinical management of patients using oxygen therapy, ventilation, and other treatment strategies, and covers some medical case reports.

Artificial intelligence (AI) offers a powerful new tool that could potentially be instrumental in controling and managing the SARS-CoV-2 virus. The papers in this feed report on the applications of AI to the current pandemic, which may be able to predict the location of the next outbreak, or facilitate new drug design.

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent preprints published on COVID-19.

Parkinson's disease (PD) is a neurodegenerative disorder caused by the progressive loss of dopaminergic neurons. Some PD-genes may be associated with astrocyte dysfunction. Discover the latest research on astrocytes in Parkinson's disease here.

Astrocytes are abundant within the central nervous system and their dysfunction has been thought to be an important contributor to some neurodegenerative diseases, in particular Huntington’s disease. Damage to these cells may make neurons more susceptible to degeneration. Here is the latest research on astrocytes and Huntington’s disease.

Brain organoids are three-dimensional in vitro cellular models of the brain that can recapitulate many processes such as the neurodevelopment. In addition, these organoids can be combined with other cell types, such as neurons and astrocytes to study their interactions in assembloids. Disease processes can also be modeled by induced pluripotent stem cell-derived organoids and assembloids from patients with neurodegenerative disorders. Discover the latest research on the models here.

Aberrant T cell activity is known to mediate considerable damage in a variety of disease states, and the immune system has been recognized to contribute to the development of neurodegenerative disorders. It is therefore important to identify the characteristics of T cells involved in the pathogenesis of neurodegenerative diseases. Discover the latest research on T cells and neurodegeneration here.

While a link has been established between RNA, RNA-binding proteins, and motor proteins, mechanisms underlying RNA trafficking are still unclear. Furthermore, interactions between cargo and motor proteins are dysregulated in microsatellite repeat expansion diseases, including Huntington’s disease. Here is the latest research focusing on RNA trafficking and neurodegeneration.

Tauopathies are neurodegenerative disorders caused due to misfolding and aggregation of the tau protein in neurofibrillary tangles in the brain. This feed focuses on the structural basis of protein pathology in tauopathies. Here is the latest research.

Neurodegenerative disorders and obesity appear to have common pathologies including neuroinflammation. Targeting common pathways may prove to be a useful treatment strategy for neurodegenerative disease. Discover the latest research on neurodegenerative disorders and obesity here.

The innate immune response is an important regulator of the downstream immune response, and it is becoming increasingly evident that immune dysfunction has impacts on the pathogenesis of multiple disease states, including neurodegeneration. Additionally, mutations in several genes involved in the innate immune response have been associated with neurodegeneration. Discover the latest research on innate immunity and neurodegeneration here.

Astrocytes are important for the health and function of the central nervous system. When these cells stop functioning properly, either through gain of function or loss of homeostatic controls, neurodegenerative diseases can occur. Here is the latest research on astrocytes and neurodegeneration.

Astrocytes are glial cells found within the CNS and are able to regenerate new neurons. They become activated during CNS injury and disease. The activation leads to the transcription of new genes and the repair and regeneration of neurons. Discover the latest research on astrocytes in repair and regeneration here.

Patients with neurodegenerative diseases often have an altered composition of the gut microbiome. Novel reports suggest that there is an extensive crosstalk between the gut microbiome and the brain, and this may influence neurodegeneration. Discover the latest research on how the gut microbiome influences neurodegeneration here.

Neurodegenerative diseases may be caused in part by triggers from peripheral body systems or inflammation mediated by brain cells other than neurons. Understanding these peripheral factors is necessary for designing treatments. Additionally, genetic tools allowing for delivery of transgenes past the blood-brain barrier are important for treatments of any CNS diseases. Discover the latest research on neurodegenerative disorders, their peripheral causes, and viral vectors for CNS delivery here.

Neurodegeneration is the progressive loss of structure or function of neurons, including neuronal death, and leads to several diseases, including Alzheimer’s and Parkinson’s. This feed focuses on the genetics and pathology of neurodegenerative diseases.

Parkinson's disease is a progressive, neurodegenerative disorder that affects both motor and cognitive function. The etiology of the disease is mostly unknown, but it probably involves both environmental and genetic. This feed focuses on profiling and defining Parkinson’s disease using biological and computational methods.

Some neurodegenerative disorders are believed to be due to RNA-induced cellular toxicity caused by the expansion of nucleotide-repeat sequences in DNA. Discover the latest research on RNA-mediated toxicity in neurodegeneration here.

Tau proteins include six highly soluble protein isoforms produced by alternative splicing from the gene MAPT (microtubule-associated protein tau). Combating tau-associated pathologies is a key focus of neurodegeneration research. Here is the latest research on tau and neurodegeneration.

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Extracellular vesicles found in human biological fluids may provide insight into the protein profiles of human neurons in various diseases, including Parkinson's disease. Here is the latest research on extracellular vesicles and Parkinson's disease.

The Neurodegeneration Challenge Network aims to provide funding for and to bring together researchers studying neurodegenerative diseases. Find the latest research from the NDCN grantees here.

Microglial proliferation and activation, as well as its concentration around amyloid plaques, is a prominent feature of Alzheimer’s disease. Here is the latest research on microglia and Alzheimer’s disease.

Asthma is a condition in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath. Discover the latest preprints here.

Cognitive neuroscience is the study of biological processes that underlie cognition and addresses the role of neural circuits in regulating cognitive activities. Here are the latest preprints on cognitive neuroscience.

Human immunodeficiency virus (HIV) is a retroviral infection that can lead to acquired immunodeficiency syndrome (AIDS). HIV can be effectively controlled through antiviral drugs to prevent progression to AIDS. Discover the latest preprints on HIV here.

Parkinson’s disease is a progressive neurodegenerative disorder that affects movement. This feed focuses on genetic screening approaches and genetic predispositions in Parkinson’s disease.

Computation neuroscience employs models, statistics, simulations, and theoretical analyses to understand mechanisms that govern neural functions. Here are the latest preprints in this domain.

This feed focuses on Type 2 Diabetes, a disease where the body doesn’t produce or respond to insulin anymore, leading to abnormal glucose levels in the blood.

Cancer genomics employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest preprints here.

The Human Tumor Atlas is a collaborative project that uses detailed maps of a variety of cancers to investigate cancer development, metastasis, and treatments. Discover the latest preprints from the Human Tumor Atlas here.

Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here are the latest preprints on the use of CRISPR-Cas system in gene editing.

MAPK pathway is a complex signaling pathway that regulates transcription, translation, cell cycle, and proliferation. Targeting this pathway has long been considered a promising strategy for cancer therapy. Here is the latest research on this pathway.

Cancer immunotherapy is an important field of research that is looking at controlling cancer and tumor growth by activating the individuals own immune system. Recent studies have utilized chimeric antigen receptor t-cell therapy, immune checkpoint inhibitors and neoantigen vaccines. Discover the latest preprints on cancer immunotherapy here.

Tissue engineering is an interdisciplinary field that aims to create, repair, and/or replace tissues and organs by using biomaterial scaffolds, growth factors, stem cells, and genetic engineering. Discover the latest preprints on tissue engineering here.

Chromatin remodeling is essential for regulation of gene expression, DNA replication, as well as DNA repair. Here is the latest research on chromatin remodeling complexes and mechanisms underlying chromatin remodeling.

Epigenetics is the study of heritable changes in gene expression that do not involve alteration of the DNA sequence. Here are the latest preprints in epigenetics.

RNA Interference (RNAi) pathway is involved in post-transcriptional gene silencing, transcriptional silencing and epigenetic silencing as well as its use as a tool for forward genetics and therapeutics. Discover the latest preprints on RNAi here.

Here are the latest preprints on physiological and in silico networks and circuits implicated in the nervous system.

This feed focuses on cellular aging with emphasis on the mitochondria, autophagy, and metabolic processes associated with aging and longevity. Here is the latest research on cell aging.

This feed focuses on preprints of projection neurons in the brain which are responsible for synthesis and release of the neurotransmitter dopamine.

This feed focuses on novel advances in medical devices used to manage type I diabetes, such as an artificial pancreas and insulin pumps.

Cerebral organoids derived from induced pluripotent stem (IPS) cells have illuminated early developmental events altered by disease processes, and may be a promising avenue for future therapies in neurodegenerative disorders. Here is the latest research on organoids and neurodegeneration.

Nanoparticles enable the delivery of substances, including nucleic acids and chemotherapeutic drugs, to a targeted region while sparing healthy tissues, thus overcoming adverse systemic effects of gene therapy or drug delivery. Here is the latest research on nanoparticle delivery.

Proteogenomics is a multi-omics research field that has the aim to efficiently integrate genomics, transcriptomics and proteomics. Here is the latest research on proteogenomics.

Adeno-associated virus (AAV)-based gene therapy is a biological vector that is being researched to be used as a potential therapeutic option. This gene therapy is designed to insert fragments of DNA into targeted cells to help treat diseases, such as hemophilia a. Discover the latest research on AAV-based gene therapy here.

Glycomics, the study of glycans and glycan-binding proteins in various biological systems, is an emerging field in the postgenome and postproteomics era. Here is the latest research.

Mammalian cells & synthetic biology describes the recent advancements in mammalian synthetic biology where new technologies and tools are developed to programm and probe mammalian cell behaviours that can lead to potential therapeutic applications. Discover the latest research on mammalian cells and synthetic biology here.

Protein function prediction methods are techniques that bioinformatics researchers use to assign biological or biochemical roles to proteins. Discover the latest research on protein function prediction here.

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Cancer immunotherapy is an important field of research that is looking at controlling cancer and tumor growth by activating the individuals own immune system. Recent studies have utilized chimeric antigen receptor t-cell therapy, immune checkpoint inhibitors and neoantigen vaccines. Discover the latest research on cancer immunotherapy here.

Circulating free DNA (cfDNA) are degraded DNA fragments released to the blood plasma. cfDNA has been shown to be a useful biomarker for a multitude of ailments other than cancer and fetal medicine. Here is the latest research on Circulating free DNA (cfDNA) sequencing.

Tissue engineering aims to create, repair, and/or replace tissues and organs by using biomaterial scaffolds, growth factors, stem cells, and genetic engineering. Here is the latest research on biomaterial scaffolds that can be used for tissue therapy.

Differences in genetic backgrounds pose a limitation to studying and inferring genetic mechanisms of diseases. These limitations can be overcome using induced pluripotent stem cell-derived isogenic models of diseases. Here is the latest research.

Adult stem cells have been extensively studied for tissue repair and regeneration. Discover the latest research on stem cell tissue repair here.

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression through inhibition of protein translation or by degradation of specific transcripts. miRNAs can regulate cardiovascular health, and be potential biomarkers or targets in cardiovascular disease. Discover the latest research on miRNAs in Cardiovascular Biology here.

Non-coding RNAs (ncRNAs) are RNA molecules that do not code for protein, but can have functional roles in regulating gene expression at the transcriptional and post-transcriptional level. Discover the latest research on the role of ncRNAs in Health and Disease.

Fluorescence in situ hybridization (FISH) is one of the major techniques used to detect of chromosomal aberrations. Here is the latest research.

Metabolomics refers to the large-scale study of profiling all metabolites in biological systems in a non-targeted manner. Here is the latest research.

Genome surgery using CRISPR genomic techniques offer the potential to correct disease-causing mutations in many neuronal disorders. Here are the latest discoveries pertaining to genome surgery and neuronal disorders.

National Institute of Allergy and Infectious Diseases (NIAID) goal is to perform leading research to understand, treat, and prevent infectious, immunologic, and allergic diseases. Follow this feed to stay updated on research from this group.

The KEMRI-Wellcome Institute - Researcher Network was formed through a partnership between Kenya Medical Research Institute formed a partnership with the Welcome Trust and the University of Oxford. Their major research themes are Clinical Research, Population health, Health Systems, Genomics and infectious disease transmission and Vaccines. Follow this feed to stay up to date on work published by this institute.

The International Cancer Genomics Consortium (ICGC) was established to investigate the genomic changes present in many forms of cancer. Follow this feed to stay up to date on research from this institute.

Institut Curie - Centre de Recherche covers multiple areas of research: the biology of radiations, cell signaling and Cancer, second Development biology, Cancer, Genetics and Epigenetics, third integrative tumor biology, immunology and environment, and fourth multiscale Physics-Biology-Chemistry and Cancer. Follow this feed to stay updated on research from this group.

The National Human Genome Research Institute (NHGRI) supports research focusing on genomics related human health and disease. To stay updated on research published by NHGRI follow this feed.

The International Cancer Genome Consortium (ICGC) was founded with the goal of mapping the genome of 25,000 primary untreated cancers. The ICGC has also pushed for the global sharing of genomic data to facilitate cancer research. Find the latest research from the ICGC here.

The Eli and Edythe L. Broad Institute of MIT and Harvard was launched to gain a better understanding of human health and disease through genomics. Find the latest research from the Broad Institute here.

Institute for Stem Cell Biology and Regenerative Medicine, at Stanford University was established in 2002 with the goal of discovering how the stem cells are created regulated, how they differentiate, and ultimately translate this knowledge into new medical therapies. Follow this feed to stay up to date on research published by the members of this institute.

The Neurodegeneration Challenge Network aims to provide funding for and to bring together researchers studying neurodegenerative diseases. Find the latest research from the NDCN grantees here.

European Bioinformatics Institute focuses both on data resource development and investigator-driven research in the field of bioinformatics. Follow this feed to stay up to date on research by this institute.

Find the latest research from the Stanford Medicine Department of Genetics here.

The Chan-Zuckerberg Biohub aims to support the fundamental research and develop the technologies that will enable physicians to cure, prevent, or manage all diseases in our childrens' lifetimes. The CZ Biohub brings together researchers from UC Berkeley, Stanford, and UCSF. Find the latest research from the CZ Biohub researcher network here.

The London School of Hygiene and Tropical Medicine involves cross-disciplinary research groups including laboratory, clinical, population and social sciences, all working to address major public and global health challenges. Their research contributes to health policy and practice in the UK and around the world. Follow this feed to stay up to date on work published by this institute.

Dana-Farber Cancer Institute focuses on advancing cancer tratment through supporting clinical trials and translational research. Follow this feed to stay up to date on research from this institute.

The aim of the Human Cell Atlas (HCA) is to build reference maps of all human cells in order to enhance our understanding of health and disease. The Seed Networks for the HCA project aims to bring together collaborators with different areas of expertise in order to facilitate the development of the HCA. Find the latest research from members of the HCA Seed Networks here.

The Collaboration for AIDS Vaccine Discovery (CAVD) focuses on designing a variety of novel HIV vaccine candidates and advancing the most promising candidates to clinical trials. Follow this feed to stay up to date on this important research from the CAVD.

The European Molecular Biology Laboratory (EMBL) research institution focusing on the fundamental understanding of basic biological processes in model organisms. Follow this feed to stay updated on research from the members of this institute.

The Immunological Genome Project (ImmGen) aims to build a gene expression database for murine immune cells. This will allow for the computational reconstruction of genetic regulatory networks across the immune system. Follow the latest research from ImmGen researchers here.

22q11.2 deletion syndrome, also known as DiGeorge syndrome, is a congenital disorder caused by a partial deletion of chromosome 22. Symptoms include heart defects, poor immune system function, a cleft palate, complications related to low levels of calcium in the blood, and delayed development. Discover the latest research on this disease here.

Tetralogy of Fallot is a congenital heart defect with an unknown cause which is typically treated by open heart surgery in the first year of life. Symptoms include bluish skin colour, heart murmur, and finger clubbing. Here is the latest research.

Hodgkin disease or Hodgkin's lymphoma is a type of lymphoma that affects the lymph system. Here is the latest research on Hodgkin disease.

Li-Fraumeni syndrome in an inherited predisposition to a range of cancers due to a mutation in the tumor suppressor gene TP53. The diagnosis is made if cancer occurs at a young age and there is also a family history of sarcoma or cancer at a young age. Find the latest research on Li-Fraumeni syndrome here.

Charcot-Marie-Tooth (CMT) disease is a hereditary motor and sensory neuropathy characterized by loss of muscle and touch sensation. Discover the latest research on CMT here.

Cystic fibrosis is an autosomal recessive disease, which is the result of a genetic defect in the cystic fibrosis transmembrane conductance regulator (cftr) gene. Here is the latest research on this disease

Fragile X syndrome is caused by an expanded CGG repeat (> 200 repeats) in the 5' untranslated portion of the fragile mental retardation 1 gene (FMR1) within the X chromosome, leading to deficiency of fragile X mental retardation protein (FMRP). It is characterized by cognitive impairment, hyperactivity, seizures, language delay, and enlargement of the ears, head, and testes. Discover the latest research on Fragile X syndrome here.

Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research on autism.

Huntington's disease is a hereditary neurodegenerative disease characterized by poor coordination and involuntary body movements. Discover the latest research on Huntington's disease here.

Turner syndrome is a syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,X (or 45,XO). Patients generally are of short stature with undifferentiated gonads (streak gonads), sexual infantilism, hypogonadism, webbing of the neck, cubitus valgus, elevated gonadotropins, decreased estradiol level in blood, and congenital heart defects. Discover the latest research on Turner syndrome here.

Glioblastoma Multiforme (GBM) is a tumor that develops from astrocytes and oligodendrocytes. Here is the latest research on mechanisms that underlie GBM and associated therapeutic approaches.

Neurofibromatosis 1 (NF1), also known as von Recklinghausen disease, is an autosomal dominant condition caused by mutations in the NF1 gene. Here is the latest research.

Marfan syndrome is an autosomal dominant disorder of connective tissue with abnormal features in the heart, the eye, and the skeleton. It is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue. Discover the latest research on Marfan syndrome here.

Multiple myeloma is a cancer of the plasma cells, which normally is involved in antibody production. Discover the latest research on Multiple myeloma here.

Retinitis pigmentosa is a hereditary, progressive degeneration of the retina due to death of rod photoreceptors initially and subsequent death of cone photoreceptors. It is characterized by deposition of pigment in the retina. Discover the latest research on retinitis pigmentosa here.

Amyotrophic Lateral Sclerosis (ALS) is a progressive nervous system disease associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS here.

Creutzfeldt-Jakob Disease is a fatal neurodegenerative disease caused by aggregation and accumulation of misfolded prion proteins. Here are the latest discoveries pertaining to this disease.

Prader-Willi Syndrome (PWS) is a rare genetic disorder caused by missing or non-working genes on chromosome 15. In infancy, symptoms include hypotonia, feeding difficulties, and delayed development; later on, affected children develop an extreme appetite, typically resulting in obesity. Here is the latest research on this complex multisystem disorder.

Castleman disease is a rare disorder that involves an overgrowth of cells in the lymph nodes. Unicentric Castleman disease affects one lymph node, usually in the chest or abdomen. Multicentric Castleman disease affects multiple lymph nodes, commonly located in the neck, collarbone, underarm and groin areas. Discover the latest research on Castleman disease here.

The Proceedings of the National Academy of Sciences (PNAS) is a peer-reviewed multidisciplinary scientific journal. Here are the latest research papers from PNAS.

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.

Science Magazine is a peer-reviewed academic journal of the American Association for the Advancement of Science. Find the latest research from Science here.

Nature is the world's leading multidisciplinary science journal. Discover the latest research from Nature here.

Discover the latest reviews in immunology research in this collection of the top immunology review journals.

Discover the latest cardiology research in this collection of the top cardiology journals.

Cell is a scientific journal publishing research across a broad range of disciplines within the life sciences field. Discover the latest research from Cell here.

Discover the latest genomics research in this collection of the top open access genomics journals.

The American Society for Biochemistry and Molecular Biology (ASBMB) includes the Journal of Biological Chemistry, Molecular & Cellular Proteomics, and the Journal of Lipid Research. Discover the latest research from ASBMB here.

Discover the latest research from the prestigious journals: Nature, Cell, and Science.

Discover the latest general biology research in this collection of the top biology journals.

Discover the latest respiratory research published by the journals from the American Thoracic Society.

Discover the latest infectious disease research in this collection of the top infectious disease journals.

Discover the latest diabetes research published by the journals from the American Diabetes Association.

Discover the latest reviews in neuroscience research in this collection of the top neuroscience review journals.

The Lancet is a peer-reviewed general medical journal published by Elsevier. Discover the latest research from the Lancet here.

Discover the latest medical research in this collection of the top medical journals.

PLOS Medicine is a peer-reviewed journal covering medical sciences and published by the Public Library of Science. Discover the latest research from PLOS Medicine here.

PLOS Biology is a peer-reviewed journal covering in the field of biology and published by the Public Library of Science. Find the latest research from PLOS Biology here.

TDP-43 is implicated in several neurodegenerative disorders including Alzheimer's disease, amyotrophic lateral sclerosis and frontotemporal lobe dementia. It has also been shown to regulate microglial phagocytosis. Here is the latest research on the role of TDP-43 and microglia in neurodegeneration.

Diffuse Neurofibrillary Tangles with Calcification (DNTC) is a rare form of presenile dementia. Here is the latest research.

microRNAs (miRNAs) are key regulatory RNAs that control gene expression in various biological processes and human diseases such as Spinocerebellar Ataxia. Here are the latest discoveries pertaining to miRNAs and this disease.

Bovine spongiform encephalopathy is a neurodegenerative disease belonging to the transmissible spongiform encephalopathies, a group of diseases including sheep scrapie and human Creutzfeldt-Jakob disease. Here is the latest research.

The blood brain barrier is important for regulating the movement of biomolecules in and out of the brain. For example, membrane transporters in the blood brain barrier can be essential for regulating drug movement and dysregulation of these processes may play a role in neurodegeneration. This feed follows the latest research on this topic.

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Creutzfeldt-Jakob Disease is a fatal neurodegenerative disease caused by aggregation and accumulation of misfolded prion proteins. Here are the latest discoveries pertaining to this disease.

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion-like mechanisms are associated with the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). Here is the latest research on ALS and prions.

The innate immune system is a first line of defense against infection. Pathological states can occur if there is over activation of the innate immune system, particularly in the brain. The excessive activation of these cells can lead to inflammation and neurodegenerative diseases. Here is the latest research on innate immunity and neurodegeneration.

Tauopathies are neurodegenerative disorders caused due to misfolding and aggregation of the tau protein in neurofibrillary tangles in the brain. This feed focuses on the structural basis of protein pathology in tauopathies. Here is the latest research.

Amyloid precursor protein (APP) proteolysis is critical for the development of Alzheimer's disease, a neurodegenerative disease associated with accumulation of amyloid plaques in the brain. Here is the latest research on APP and Alzheimer's disease.

Tau mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17) are associated with changes in alternative RNA splicing. Here is the latest research on RNA & Tau in Frontotemporal Dementia.

Alzheimer's disease is a neurodegenerative disease. This feed focuses on the underlying role of tau proteins and TAR DNA-binding protein 43, as well as other genetic factors, in Alzheimer's disease.

Prion diseases or transmissible spongiform encephalopathies are rare progressive neurogenerative diseases caused by misfolded prion proteins. Here is the latest research in this domain.