Allergy & Hypersensitivity
Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.
Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.
Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.
Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.
This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.
Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.
Chemokines are a subset of cytokines which induce chemotaxis in cells expressing chemokine receptors. Chemokines can be broadly categorized into two functional subgroups, homeostatic (basal expression in lymphoid tissues for surveillance purposes) or inflammatory (released during injury to recruit immune effector cells). Chemokine receptors are G-protein coupled receptors which, upon chemokine binding, induce calcium influx into the cell. Find the latest research on chemokines and chemokine receptors here.
Childhood asthma is a chronic inflammatory disease that affects the respiratory airways. There are many factors that influence the susceptibility for the development of childhood asthma such as infections, including respiratory syncytial virus and gene-environment interactions. Here is the latest research on childhood asthma.
Cytokines are proteins that are released by a subset of immune cells and play a role in intercellular communication, cell proliferation, differentiation, and survival. Discover the latest research on the influence of cytokine signaling on transcription here.
Delayed hypersensitivity reactions are inflammatory reactions initiated by mononuclear leukocytes. Delayed hypersensitivity is a major mechanism of defense against various intracellular pathogens, including mycobacteria, fungi, and certain parasites, and it occurs in transplant rejection and tumor immunity. Discover the latest research on delayed hypersensitivity here.
Drug hypersensitivity is an immune-mediated reaction to a drug. Symptoms range from mild to severe and include rash, anaphylaxis, and serum sickness. Discover the latest research on drug hypersensitivity here.
Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation of inflammatory responses, immune cell regulation, and defense against pathogens. Discover the latest research on Eosinophils here.
Fc receptors (fcrs) mediate a plethora of biological functions as diverse as antigen presentation, phagocytosis, cytotoxicity, induction of inflammatory cascades and modulation of immune responses. Discover the latest research on Fc Receptors here.
Food hypersensitivity is divided into food allergy and non-allergic food hypersensitivity, the latter of which is also known as food intolerance. Food allergy is an abnormal immune response to food while food intolerance is a detrimental reaction, often delayed, to a food, beverage, food additive, or compound found in foods that produces symptoms in one or more body organs and systems. Discover the latest research on food hypersensitivity.
Food toxicology is the study of potential toxins or harmful synthetic agents in food and how these can lead to adverse health outcomes in living organisms, including humans. Here is the latest research on food toxicology.
Immune tolerance happens when the immune system is not responsive to a substance or organism and does not elicit an immune response. This is a normal physiological response for some antigens, especially when detecting self from non-self. This has been a potential area of therapy for some disorders. Here is the latest research on immune tolerance.
Mast cells are key components involved in allergic reactions. They release chemical mediators that are responsible for the clinical symptoms of an allergic reaction. These chemical mediators include histamine, cytokines, leukotrienes and many others. Discover the latest research on mast cells in allergy here.
Myastocytosis is a heterogenous group of disorders characterized by the abnormal increase of mast in only the skin, in extracutaneous tissues involving multiple organs, or in solid tumors. Discover the latest research myastocytosis here.
The maternal-fetal interface encompasses the decidua from the mother and the placenta from the developing fetus. Throughout pregnancy important cells and receptors are located on the interface. Cells including fetal trophoblasts and toll-like receptors are of great importance. Here is the latest research on the maternal-fetal interface.
Respiratory hypersensitivity is a form of hypersensitivity affecting the respiratory tract. Discover the latest research on respiratory hypersensitivity here.
Schoenlein-Henoch purpura is a systemic non-thrombocytopenic purpura caused by hypersensitivity vasculitis and deposition of IgA-containing immune complexes within the blood vessels throughout the body, including those in the kidney. Discover the latest research on Schoenlein-Henoch purpura here.
Urticaria, also known as hive, is a vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. Discover the latest research on urticaria here.