Total artificial hearts (TAH) and ventricular assist devices (VADs) provide cardiac support for patients with end-stage heart disease and have significantly improved the survival of these patients. Discover the latest research on Artificial Heart and Ventricular Assist Devices here.
Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.
Cardiac amyloidosis is a myocardial disease characterized by extracellular amyloid infiltration throughout the heart. Discover the latest research on cardiac amyloidosis here.
Cardiac organoids are 3D organ-like structures that can be derived from patients with cardiovascular diseases and are important disease models for drug discovery. Discover the latest research on Cardiac Organoids here.
Cardiac regeneration enables the repair of irreversibly damaged heart tissue using cutting-edge science, including stem cell and cell-free therapy. Discover the latest research on cardiac regeneration here.
Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.
Cardiogenic shock is a devastating consequence of acute myocardial infarction and is associated with an extremely high mortality. Here is the latest research.
Cardiomegaly, known as an enlarged heart, is a multifactorial disease with different pathophysiological mechanisms. Hypertension, pregnancy, exercise-induced and idiopathic causes are some mechanisms of cardiomegaly. Discover the latest research of cardiomegaly here.
Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.
Endocardial fibroelastosis is a disease characterized by a prominent proliferation of dense collagenous and elastic tissue in the endocardium with the occurrence of congestive heart failure and death in early life. Here is the latest research.
Epigenetic regulation of gene expression is important in determining cell fate and identity, and is a factor in stem cell studies involving cardiomyocyte differentiation. Discover the latest research on Epigenetics in Cardiomyocyte Differentiation here.
Ischemia results from lack of blood flow to a particular region or organ and can have serious consequences, including myocardial infarction. Different therapeutic interventions including stents, percutaneous coronary intervention and angioplasty may be used for treatment. Discover the latest research on ischemia here.
Ischemia and reperfusion is a pathological condition characterized by an initial restriction of blood supply to an organ followed by the subsequent restoration of perfusion and concomitant reoxygenation. Restoration of blood flow and reoxygenation is frequently associated with an exacerbation of tissue injury and a profound inflammatory response (called ‘reperfusion injury’). Discover the latest research on ischemia and reperfusion here.
Establishing cardiomyocytes derived from human induced pluripotent stem cells has great potential as a cell source for therapeutic applications, such as regenerative medicine. Discover the latest research on Molecular Drivers of Cardiomyocyte Maturation here.
Myocarditis is an acute or chronic inflammatory disease of the myocardium which can be viral, postinfectious immune or primarily organ-specific autoimmune. Discover the latest research on myocarditis here.
Omics are used to understand the gene expression profile and proteomics of many diseases. This feed focuses on the omics of myocardial infarction and heart failure. Here are the latest discoveries pertaining to this disease.
Paediatric cardiomyopathy and heart failure are distinct but frequently associated conditions, which have a high mortality. Here is the latest research.
Stem cells have the therapeutic potential for cardiac repair and regeneration after myocardial infarction. Discover the latest research in Stem Cells In Cardiac Repair here.