Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.
Apoptotic caspases belong to the protease enzyme family and are known to play an essential role in inflammation and programmed cell death. Here is the latest research.
mRNA-based technology is being studied as a potential technology that could be used to reprogram cell fate. This technique provides the potential to generate safe reprogrammed cells that can be used for clinical applications. Here is the latest research on cell fate conversion by mRNA.
Chromatin regulators affect gene expression by influencing the access of proteins such as transcription factors to DNA. Here is the latest research on the role of chromatin regulating proteins on cellular differentiation.
A dynamic cytoskeleton is critical for the generation of cell polarity. This feed focuses on cell polarity and the cytoskeleton, including actin and microtubular cytoskeletal organization.
Embryonic neural stem cells can be used to investigate the effect of different toxins and molecules on the proliferation and differentiation of these cells. Discover the latest research of embryonic neural stem cells here.
Glial cells play an essential role in maintaining brain homeostasis, forming myelin, and providing support and protection for neurons. Follow new research into glia cell differentiation with this feed.
The homeobox genes (Hox gene family) encode for homeodomain-containing transcription factors, which are important in the regulation of embryonic development and cell differentiation. They have a conserved DNA binding domain that are found in the family of hox genes. Discover the latest research on hox gene family here.
Induced pluripotent stem cells (iPSCs) may be obtained by direct reprogramming of different somatic cells to a pluripotent state by forced expression of a handful of transcription factors, These cells have similar properties to those of embryonic stem cells (escs) but bypass the ethical concerns of embryo destruction and can be exploited for both research and clinical applications.Discover the latest research on iPSC here.
Mesenchymal stem cells are multipotent stem cells isolated from bone marrow with the capacity to differentiate into a variety of cell types and are being investigated for a number of potential therapeutic applications. Discover the latest research on mesenchymal stem cells here.
Neural stem cells are self-renewing, multipotent cells that are present in both the embryonic and adult brain. Several factors, including metabolism, have been shown to regulate proliferation, differentiation, and quiescence of neural stem cells. Here is the latest research.
Pluripotent stem cells (PSCs) are progenitor cells that can give rise to three basic layers of the body, thus potentially allowing the production of any cells or tissues needed by the body for repair. Here is the latest research on the PSCs in development and disease.
This feed focuses on the Polycomb Group Proteins, which are protein complexes that are recruited to chromatin and are involved in the deposition of repressive histone marks, leading to gene repression.
Stem cell niches are dynamic microenvironments that balance stem cell activity to maintain tissue homeostasis and repair throughout the lifetime of an organism. Here is the latest research.
Transglutaminase 2 is a multifunctional and protein crosslinking enzyme present in the white adipose tissue. Recent studies have implicated this protein as a novel negative regulator of adipogenesis. Here is the latest research.
Wnt signal transduction pathway is regulated by several molecules and is critical for embryonic development, cell proliferation, differentiation, and tissue patterning. Here is the latest research on Wnt signaling.