Coronary Artery Disease
Antianginal drugs, including nitrates, beta-blockers, and calcium channel blockers, are used in the treatment of angina pectoris. Here is the latest research on their use and their mechanism of action.
Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.
Apolipoprotein E (APOE) is a protein involved in fat metabolism and associated with the pathogenesis of Alzheimer's disease and cardiovascular disease. Here is the latest research on APOE phenotypes.
Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.
Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.
Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.
Sensitive and accurate biomarkers used in cardiovascular risk prediction can potentially be used to manage the risk of cardiovascular disease. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here.
This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.
Cardiomegaly, known as an enlarged heart, is a multifactorial disease with different pathophysiological mechanisms. Hypertension, pregnancy, exercise-induced and idiopathic causes are some mechanisms of cardiomegaly. Discover the latest research of cardiomegaly here.
Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.
Cell adhesion molecules expressed on the vascular endothelium and circulating leukocytes in response to inflammatory stimuli are implicated in atherosclerosis. Here is the latest research.
Coronary artery aneurysms are the dilation of the coronary arteries that supply the heart tissue with blood and nutrients. The dilation exceeds 1.5 times the normal artery size. Complications can occur if these aneurysms rupture. Here is the latest research on coronary artery aneurysms.
Coronary artery disease is extremely prevalent in western societies and is the number one cause of morbidity and mortality industrialized countries. Known risk factors include hypertension, smoking and dyslipidemia. Discover the latest research on coronary artery disease here.
Coronary vasospasm is the abnormal contraction of the coronary arteries on the epicardium. The constriction can lead to myocardial ischemia and life threatening cardiac arrhythmias. Discover the latest research on coronary vasospasms here.
Endothelin receptors are G-protein coupled receptors that mediate smooth muscle contraction or relaxation which in turn regulate blood pressure. Discover the latest research on endothelins and their receptors here.
Blood pressure is tightly regulated by blood vessel radius, which is established by hormones and/or peptides binding to GPCRs (G-protein-coupled receptors). Discover the latest research on GPCRs in blood pressure regulation here
Ischemia results from lack of blood flow to a particular region or organ and can have serious consequences, including myocardial infarction. Different therapeutic interventions including stents, percutaneous coronary intervention and angioplasty may be used for treatment. Discover the latest research on ischemia here.
Ischemia and reperfusion is a pathological condition characterized by an initial restriction of blood supply to an organ followed by the subsequent restoration of perfusion and concomitant reoxygenation. Restoration of blood flow and reoxygenation is frequently associated with an exacerbation of tissue injury and a profound inflammatory response (called ‘reperfusion injury’). Discover the latest research on ischemia and reperfusion here.
Myocardial infarctions occur when blood flow to a part of the heart decreases or stops. Here is the latest research on factors and mechanisms that modulate the risk of myocardial infarctions.
Omics are used to understand the gene expression profile and proteomics of many diseases. This feed focuses on the omics of myocardial infarction and heart failure. Here are the latest discoveries pertaining to this disease.
Peripheral artery disease (PAD), which comprises atherosclerosis of the abdominal aorta, iliac, and lower-extremity arteries, is a common circulatory condition in which narrowed arteries reduce blood flow to the limbs. Discover the latest research on peripheral artery disease here
Spontaneous coronary artery dissection is a rare cause of acute coronary syndrome and sudden cardiac death. Here is the latest research.
Statins or HMG-CoA reductase inhibitors, are used clinically to lower cholesterol levels and have been associated with decreased risk of heart disease. Discover the latest research on Statin Medications & Heart Disease here.
Vascular disease prevention is important to reduce the incidence of cardiovascular events and the high morbidity and mortality. Here is the latest research.
Vascular imaging makes it possible to quantify the number and spacing of blood vessels, measure blood flow and vascular permeability, and analyze cellular and molecular abnormalities in blood vessel walls. Discover the latest research on vascular imaging here.