Dementia & Cognitive Neurology


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  • Age-related dementia (Alzheimer's disease) results from the destructive impact of the pulse on cerebral vasculature. Evidence is reviewed that the neuropathology of the dementia is caused by the breakdown of small cerebral vessels (silent microbleeds), that the microbleeds result from pulse-induced damage to the cerebral vessels, and that pulse becomes increasingly destructive with age, because of the age-related stiffening of the aorta and great arteries, which causes an increase in the intensity of the pressure pulse. Discover the latest research on age-related dementia here.
    Age-related Dementia
    Fast Growing

    Age-related dementia (Alzheimer's disease) results from the destructive impact of the pulse on cerebral vasculature. Evidence is reviewed that the neuropathology of the dementia is caused by the breakdown of small cerebral vessels (silent microbleeds), that the microbleeds result from pulse-induced damage to the cerebral vessels, and that pulse becomes increasingly destructive with age, because of the age-related stiffening of the aorta and great arteries, which causes an increase in the intensity of the pressure pulse. Discover the latest research on age-related dementia here.

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  • This feed focuses on epidemiology of aging and aging-related conditions, including Alzheimer’s disease, dementia, and age-associated cognitive impairment. Here is the latest research.
    Aging Epidemiology
    Fast Growing

    This feed focuses on epidemiology of aging and aging-related conditions, including Alzheimer’s disease, dementia, and age-associated cognitive impairment. Here is the latest research.

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  • This feed focuses on aging epidemiology and genetic, epigenetic, and proteomic aspects underlying aging, as well as aging- associated biomarkers. Here the latest research in this domain.
    Aging Genetics
    Fast Growing

    This feed focuses on aging epidemiology and genetic, epigenetic, and proteomic aspects underlying aging, as well as aging- associated biomarkers. Here the latest research in this domain.

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  • Apolipoprotein E (APOE) polymorphic alleles are major genetic risk factors for Alzheimer's Disease. Discover the latest research on APOE and other genetic determinants of Alzheimer's Disease here.
    Alzheimer's Disease: APOE
    Fast Growing

    Apolipoprotein E (APOE) polymorphic alleles are major genetic risk factors for Alzheimer's Disease. Discover the latest research on APOE and other genetic determinants of Alzheimer's Disease here.

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  • Amyloid precursor protein proteolysis is critical for the development of Alzheimer's disease, a neurodegenerative disease associated with accumulation of amyloid plaques. Here is the latest research.
    Alzheimer's Disease: APP
    Going Viral

    Amyloid precursor protein proteolysis is critical for the development of Alzheimer's disease, a neurodegenerative disease associated with accumulation of amyloid plaques. Here is the latest research.

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  • Alzheimer's disease (AD) is a chronic neurodegenerative disease associated with accumulation of amyloid plaques, which are comprised of amyloid beta. Here is the latest research in this field.
    Alzheimer's Disease: Abeta
    Going Viral

    Alzheimer's disease (AD) is a chronic neurodegenerative disease associated with accumulation of amyloid plaques, which are comprised of amyloid beta. Here is the latest research in this field.

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  • Alzheimer's disease is a chronic neurodegenerative disease which can be studied using various experimental systems. This feed focuses on animal models used for Alzheimer's disease research.
    Alzheimer's Disease: Animal models

    Alzheimer's disease is a chronic neurodegenerative disease which can be studied using various experimental systems. This feed focuses on animal models used for Alzheimer's disease research.

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  • Alzheimer's disease is a chronic neurodegenerative disease. This feed focuses on early markers, as well as environmental, pharmacological, and drug-response biomarkers associated with this disease.
    Alzheimer's Disease: Early Markers

    Alzheimer's disease is a chronic neurodegenerative disease. This feed focuses on early markers, as well as environmental, pharmacological, and drug-response biomarkers associated with this disease.

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  • The feed focuses on the role of dysfunctional endosomal trafficking in Alzheimer’s Disease and the potential for targeting the endosome as a therapeutic target.
    Alzheimer's Disease: Endosomes

    The feed focuses on the role of dysfunctional endosomal trafficking in Alzheimer’s Disease and the potential for targeting the endosome as a therapeutic target.

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  • Genes and microglia are associated with the risk of developing and the progression of conditions such as Alzheimer's Disease (AD). Here are the latest discoveries pertaining to this disease.
    Alzheimer's Disease: Genes&Microglia

    Genes and microglia are associated with the risk of developing and the progression of conditions such as Alzheimer's Disease (AD). Here are the latest discoveries pertaining to this disease.

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  • Alzheimer's disease is a chronic neurodegenerative disease. Discover genetic and epigenetic aspects of Alzheimer’s disease, including genetic markers and genomic structural variations here.
    Alzheimer's Disease: Genetics

    Alzheimer's disease is a chronic neurodegenerative disease. Discover genetic and epigenetic aspects of Alzheimer’s disease, including genetic markers and genomic structural variations here.

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  • Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.
    Alzheimer's Disease: MS4A

    Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.

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  • Alzheimer's disease (AD) is a chronic neurodegenerative disease. Here is the latest research on neuroimaging modalities, including magnetic resonance imaging and positron emission tomography, in AD.
    Alzheimer's Disease: Neuroimaging

    Alzheimer's disease (AD) is a chronic neurodegenerative disease. Here is the latest research on neuroimaging modalities, including magnetic resonance imaging and positron emission tomography, in AD.

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  • RNA regulation involves several mechanisms that are used by cells to decreases or increase the production of RNA. Issues with RNA regulation are associated with Alzheimer's Disease (AD). Here are the latest discoveries pertaining to RNA regulation and this disease.
    Alzheimer's Disease: RNA Regulation
    Going Viral

    RNA regulation involves several mechanisms that are used by cells to decreases or increase the production of RNA. Issues with RNA regulation are associated with Alzheimer's Disease (AD). Here are the latest discoveries pertaining to RNA regulation and this disease.

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  • RNA sequencing is used to reveal the presence and quantity of RNA in a given sample. In this feed, RNA sequencing investigates the genetic and molecular mechanisms related to the pathophysiology of Alzheimer's disease (AD). Here are the latest discoveries pertaining to RNA sequencing and this disease.
    Alzheimer's Disease: RNA Sequencing
    Fast Growing

    RNA sequencing is used to reveal the presence and quantity of RNA in a given sample. In this feed, RNA sequencing investigates the genetic and molecular mechanisms related to the pathophysiology of Alzheimer's disease (AD). Here are the latest discoveries pertaining to RNA sequencing and this disease.

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  • Alzheimer's disease is a chronic neurodegenerative disease. This feed focuses on the underlying role of Tau proteins and TAR DNA-binding protein 43, as well as other genetic factors, in Alzheimer's.
    Alzheimer's Disease: Tau & TDP-43

    Alzheimer's disease is a chronic neurodegenerative disease. This feed focuses on the underlying role of Tau proteins and TAR DNA-binding protein 43, as well as other genetic factors, in Alzheimer's.

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  • Transcription involves copying (transcribing) the gene's DNA sequence into RNA. Impaired transcription is associated with the pathogenesis and progression of conditions such as Alzheimer's disease (AD). Here are the latest discoveries pertaining to transcription and this disease.
    Alzheimer's Disease: Transcription

    Transcription involves copying (transcribing) the gene's DNA sequence into RNA. Impaired transcription is associated with the pathogenesis and progression of conditions such as Alzheimer's disease (AD). Here are the latest discoveries pertaining to transcription and this disease.

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  • Amyloid beta is neurotoxic and a major component of plaques in Alzheimer’s disease. Accumulation induces neurotoxic effects including oxidative damage and mitochondrial dysfunction. Breakdown of amyloid is important to prevent the development of Alzheimer’s disease. Here is the latest research on amyloid beta deposition and degradation.
    Amyloid Beta Deposition & Degradation

    Amyloid beta is neurotoxic and a major component of plaques in Alzheimer’s disease. Accumulation induces neurotoxic effects including oxidative damage and mitochondrial dysfunction. Breakdown of amyloid is important to prevent the development of Alzheimer’s disease. Here is the latest research on amyloid beta deposition and degradation.

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  • Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.
    Aphasia
    Going Viral

    Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.

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  • Apolipoprotein E (APOE) is a protein involved in fat metabolism and associated with the pathogenesis of Alzheimer's disease and cardiovascular disease. Here is the latest research on APOE phenotypes.
    ApoE Phenotypes
    Fast Growing

    Apolipoprotein E (APOE) is a protein involved in fat metabolism and associated with the pathogenesis of Alzheimer's disease and cardiovascular disease. Here is the latest research on APOE phenotypes.

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  • The relationship between astrocytes and amyloid has been suggested in some neurological diseases such as Alzheimer’s disease. Neuronal damage stimulates the activation of reactive astrocytes, which may the source of amyloid that forms in Alzheimer’s. Here is the latest research on astrocytes and amyloid.
    Astrocytes & Amyloid
    Influential

    The relationship between astrocytes and amyloid has been suggested in some neurological diseases such as Alzheimer’s disease. Neuronal damage stimulates the activation of reactive astrocytes, which may the source of amyloid that forms in Alzheimer’s. Here is the latest research on astrocytes and amyloid.

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  • Here is the latest research on intrinsic and extrinsic factors, as well as pathways and mechanisms that underlie aging in the central nervous system.
    Brain Aging

    Here is the latest research on intrinsic and extrinsic factors, as well as pathways and mechanisms that underlie aging in the central nervous system.

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  • Apolipoprotein E (APOE) is a protein involved in fat metabolism and associated with the pathogenesis of neurodegenerative and cardiovascular diseases. This feed focuses on the role of this protein in cerebrovasculature and cerebrovascular dysfunction.
    Cerebrovasculature & ApoE
    Fast Growing

    Apolipoprotein E (APOE) is a protein involved in fat metabolism and associated with the pathogenesis of neurodegenerative and cardiovascular diseases. This feed focuses on the role of this protein in cerebrovasculature and cerebrovascular dysfunction.

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  • This feed focuses on the role of environmental and genetic factors including environmental policies, disease susceptibility, and socioeconomic status on cognitive decline. Here is the latest research.
    Cognitive Decline: Environmental And Genetic Factors
    Going Viral

    This feed focuses on the role of environmental and genetic factors including environmental policies, disease susceptibility, and socioeconomic status on cognitive decline. Here is the latest research.

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  • This feed focuses on complex memory functions, including remote memory, recognition memory, and spatial cognition. Here is the latest research.
    Complex Memory Functions
    Going Viral

    This feed focuses on complex memory functions, including remote memory, recognition memory, and spatial cognition. Here is the latest research.

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  • Creutzfeldt-Jakob Disease is a fatal neurodegenerative disease caused due to aggregation and accumulation of misfolded prion proteins. Here are the latest discoveries pertaining to this disease.
    Creutzfeldt-Jakob Disease
    Influential

    Creutzfeldt-Jakob Disease is a fatal neurodegenerative disease caused due to aggregation and accumulation of misfolded prion proteins. Here are the latest discoveries pertaining to this disease.

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  • While abilities like vocabulary resist aging, other abilities such as memory, decision-making, and reasoning, gradually decline. Here is the latest research on decision-making and cognitive aging.
    Decision Making & Cognitive Aging

    While abilities like vocabulary resist aging, other abilities such as memory, decision-making, and reasoning, gradually decline. Here is the latest research on decision-making and cognitive aging.

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  • This feed focuses on the impact of insulin resistance, caloric restriction, cytokine singling, and metabolism on dementia and neurodegenerative diseases. Here is the latest research in this domain.
    Dementia & Neurodegenerative Diseases

    This feed focuses on the impact of insulin resistance, caloric restriction, cytokine singling, and metabolism on dementia and neurodegenerative diseases. Here is the latest research in this domain.

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  • Epidemiological data indicates that a significant portion of the diabetic population exhibits brain changes that are hallmarks of Alzheimer’s disease and vascular dementia. However, direct biological links remain incompletely understood. Here is the latest research.
    Diabetes and Alzheimer's Disease

    Epidemiological data indicates that a significant portion of the diabetic population exhibits brain changes that are hallmarks of Alzheimer’s disease and vascular dementia. However, direct biological links remain incompletely understood. Here is the latest research.

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  • Diffuse Neurofibrillary Tangles with Calcification (DNTC) is a rare form of presenile dementia. Here is the latest research.
    Diffuse Neurofibrillary Tangles with Calcification
    Fast Growing

    Diffuse Neurofibrillary Tangles with Calcification (DNTC) is a rare form of presenile dementia. Here is the latest research.

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  • Microglial cells are instrumental in the maintenance of homeostasis in the CNS and can contribute to neurodegenerative disorders. Epigenetic mechanisms and transcriptional regulation may be potential therapeutic targets for their activation or suppression. Discover the latest research on epigenetic regulation of microglial functions here.
    Epigenetic Regulation of Microglia Functions
    Fast Growing

    Microglial cells are instrumental in the maintenance of homeostasis in the CNS and can contribute to neurodegenerative disorders. Epigenetic mechanisms and transcriptional regulation may be potential therapeutic targets for their activation or suppression. Discover the latest research on epigenetic regulation of microglial functions here.

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  • The extracellular space (ECS) in brain occupies approximately twenty percent of the brain volume and is dynamic and highly regulated. Here is the latest research on ECS in the brain.
    Extracellular Space: Brain

    The extracellular space (ECS) in brain occupies approximately twenty percent of the brain volume and is dynamic and highly regulated. Here is the latest research on ECS in the brain.

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  • Fragile X-associated tremor/ataxia syndrome (FXTAS) is caused by the expansion of CGG triple repeat in the FMR1 gene and characterized by movement problems and cognitive impairment. Here is the latest research.
    Fragile X-associated tremor/ataxia syndrome
    Influential

    Fragile X-associated tremor/ataxia syndrome (FXTAS) is caused by the expansion of CGG triple repeat in the FMR1 gene and characterized by movement problems and cognitive impairment. Here is the latest research.

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  • Frontotemporal dementia (FTD) refers to disorders caused by progressive neuronal loss in the frontal and temporal lobes of the brain. Here is the latest research on FTD and FTD-associated disorders.
    Frontotemporal Dementia

    Frontotemporal dementia (FTD) refers to disorders caused by progressive neuronal loss in the frontal and temporal lobes of the brain. Here is the latest research on FTD and FTD-associated disorders.

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  • Frontotemporal lobar degeneration or frontotemporal dementia refers to a group of uncommon disorders that occur as a result of progressive nerve cell loss in the frontal and temporal lobes of the brain. Here is the latest research.
    Frontotemporal Lobar Degeneration
    Going Viral

    Frontotemporal lobar degeneration or frontotemporal dementia refers to a group of uncommon disorders that occur as a result of progressive nerve cell loss in the frontal and temporal lobes of the brain. Here is the latest research.

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  • GRIP1 is a glutamate receptor interacting protein 1 and myeloid cells consists of granulocytes and monocytes, before they have differentiated and are derived from hematopoietic stem cells. The interaction between GRIP1 and myeloid cells in inflammation is in the early stages. Here is the latest research on GRIP1 and myeloid cells in inflammation.
    GRIP1 in Myeloid Cells in Neuroinflammation

    GRIP1 is a glutamate receptor interacting protein 1 and myeloid cells consists of granulocytes and monocytes, before they have differentiated and are derived from hematopoietic stem cells. The interaction between GRIP1 and myeloid cells in inflammation is in the early stages. Here is the latest research on GRIP1 and myeloid cells in inflammation.

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  • Gerstmann-Straussler-Scheinker disease is a rare neurodegenerative disorder caused by prions and characterized by symptoms associated with prion-associated diseases. Here is the latest research.
    Gerstmann-Straussler-Scheinker Disease

    Gerstmann-Straussler-Scheinker disease is a rare neurodegenerative disorder caused by prions and characterized by symptoms associated with prion-associated diseases. Here is the latest research.

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  • Gut microbiota composition has been implicated in neuroinflammatory responses, as well as brain aging and brain-aging related diseases like amyloid neuropathies. Here is the latest research.
    Gut Microbiota And Brain In Aging

    Gut microbiota composition has been implicated in neuroinflammatory responses, as well as brain aging and brain-aging related diseases like amyloid neuropathies. Here is the latest research.

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  • The formation of blood cells, hematopoiesis, has been exploited for the potential use as a therapy in Alzheimer’s disease. Decreased levels of lymphocytes and proteins involved in stem cell recruitment are found in early stages of Alzheimer’s disease. Here is the latest research on hematopoiesis and Alzheimer’s disease.
    Hematopoiesis & Alzheimer's Disease
    Fast Growing

    The formation of blood cells, hematopoiesis, has been exploited for the potential use as a therapy in Alzheimer’s disease. Decreased levels of lymphocytes and proteins involved in stem cell recruitment are found in early stages of Alzheimer’s disease. Here is the latest research on hematopoiesis and Alzheimer’s disease.

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  • Hereditary spastic paraplegia is a neurodegenerative disorder characterized by spastic paraplegia, cognitive impairment, peripheral neuropathy, and progressive spasticity of lower limbs. Here is a latest research.
    Hereditary Spastic Paraplegia

    Hereditary spastic paraplegia is a neurodegenerative disorder characterized by spastic paraplegia, cognitive impairment, peripheral neuropathy, and progressive spasticity of lower limbs. Here is a latest research.

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  • Huntington disease is a hereditary neurodegenerative disease characterized by poor coordination and involuntary body movements. Discover the latest research on Huntington disease here.
    Huntington Disease

    Huntington disease is a hereditary neurodegenerative disease characterized by poor coordination and involuntary body movements. Discover the latest research on Huntington disease here.

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  • The innate immune system is a first line of defense against infection. Pathological states can occur if there is over activation of the innate immune system, particularly in the. The excessive activation of these cells can lead to inflammation and neurodegenerative diseases. Here is the latest research on innate immunity and neurodegeneration.
    Innate Immunity: Neurodegeneration

    The innate immune system is a first line of defense against infection. Pathological states can occur if there is over activation of the innate immune system, particularly in the. The excessive activation of these cells can lead to inflammation and neurodegenerative diseases. Here is the latest research on innate immunity and neurodegeneration.

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  • Fatal familial insomnia is a familial prion disease linked to a mutation of the prion protein gene. Here is the latest research on this rare genetic degenerative brain disorder.
    Insomnia Familial Fatal

    Fatal familial insomnia is a familial prion disease linked to a mutation of the prion protein gene. Here is the latest research on this rare genetic degenerative brain disorder.

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  • Interactomics is the intersection of bioinformatics and biology concerned with investigating the interaction and the consequences of these interactions between proteins in a cell. Here is the latest research on interactomic data in neurodegeneration.
    Interactomics in Neurodegeneration

    Interactomics is the intersection of bioinformatics and biology concerned with investigating the interaction and the consequences of these interactions between proteins in a cell. Here is the latest research on interactomic data in neurodegeneration.

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  • Lewy Body Disease, associated with abnormal deposits of proteins like alpha-synuclein in the brain, causes a decline in mental abilities. Here is the latest on this progressive neurological disorder.
    Lewy Body Disease

    Lewy Body Disease, associated with abnormal deposits of proteins like alpha-synuclein in the brain, causes a decline in mental abilities. Here is the latest on this progressive neurological disorder.

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  • Lichtheim's disease or subacute combined degeneration of spinal cord is a degenerative disease associated with deficiencies in vitamin B12, vitamin E, and copper. Here is a latest research.
    Lichtheim's Disease
    Fast Growing

    Lichtheim's disease or subacute combined degeneration of spinal cord is a degenerative disease associated with deficiencies in vitamin B12, vitamin E, and copper. Here is a latest research.

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  • Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Whilst some key players seem to have been identified so far, the mechanisms that underlie prion propagation to the brain are still not fully understood. Here is the latest research pertaining to mechanisms of prion propagation.
    Mechanisms of Prion Propagation

    Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Whilst some key players seem to have been identified so far, the mechanisms that underlie prion propagation to the brain are still not fully understood. Here is the latest research pertaining to mechanisms of prion propagation.

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  • Protein misfolding is the primary cause of several neurodegenerative disease, including Alzheimer’s and Parkinson’s disease. Here is the latest research.
    Misfolded Proteins: ND

    Protein misfolding is the primary cause of several neurodegenerative disease, including Alzheimer’s and Parkinson’s disease. Here is the latest research.

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  • Misfolding and aggregation of proteins can lead to several diseases. For instance, misfolding of prion or tau proteins are associated with several neurodegenerative diseases. Here is the latest research on diseases caused by protein misfolding and aggregation.
    Misfolding & Aggregation Diseases

    Misfolding and aggregation of proteins can lead to several diseases. For instance, misfolding of prion or tau proteins are associated with several neurodegenerative diseases. Here is the latest research on diseases caused by protein misfolding and aggregation.

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  • Prion diseases are fatal neurodegenerative and infectious disorders characterized by structural transition of the host-encoded cellular prion protein into the aberrantly folded pathologic isoform of the protein. Here is the latest research on molecular diagnostic strategies for prion diseases.
    Molecular diagnostic strategies in prion disease
    Going Viral

    Prion diseases are fatal neurodegenerative and infectious disorders characterized by structural transition of the host-encoded cellular prion protein into the aberrantly folded pathologic isoform of the protein. Here is the latest research on molecular diagnostic strategies for prion diseases.

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  • Myeloid cells in the CNS are innate immune cells that are essential for brain development and maintenance. Here is the latest research on myeloid cells, including microglia, in neuroinflammation.
    Myeloid Cells And Neuroinflammation
    Influential

    Myeloid cells in the CNS are innate immune cells that are essential for brain development and maintenance. Here is the latest research on myeloid cells, including microglia, in neuroinflammation.

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  • Myoclonic cerebellar dyssynergia is a rare neurodegenerative disorder characterized by myoclonus, cognitive impairment, epilepsy, and ataxia. Here is the latest research.
    Myoclonic Cerebellar Dyssynergia

    Myoclonic cerebellar dyssynergia is a rare neurodegenerative disorder characterized by myoclonus, cognitive impairment, epilepsy, and ataxia. Here is the latest research.

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  • This feed focuses on genetic aspects of neurodegeneration and aging, with emphasis on the role of protein aggregates in neurodegenerative diseases including Alzhiemer’s. Here is the latest research.
    Neurodegeneration And Aging

    This feed focuses on genetic aspects of neurodegeneration and aging, with emphasis on the role of protein aggregates in neurodegenerative diseases including Alzhiemer’s. Here is the latest research.

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  • Neurodegeneration is the progressive loss of structure or function of neurons, including neuronal death, and leads to several diseases, including Alzheimer’s and Parkinson’s. This feed focuses on the genetic alterations that underlie neurodegeneration.
    Neurodegeneration: Genetics

    Neurodegeneration is the progressive loss of structure or function of neurons, including neuronal death, and leads to several diseases, including Alzheimer’s and Parkinson’s. This feed focuses on the genetic alterations that underlie neurodegeneration.

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  • TDP43 is is implicated in several neurodegenerative disorders including Alzheimer's disease, amyotrophic lateral sclerosis and frontotemporal lobe dementia. It has also been shown to regulate microglial phagocytosis. Here is the latest research on the role of TDP43 and microglia in neurodegeneration.
    Neurodegeneration: Microglia & TDP-43

    TDP43 is is implicated in several neurodegenerative disorders including Alzheimer's disease, amyotrophic lateral sclerosis and frontotemporal lobe dementia. It has also been shown to regulate microglial phagocytosis. Here is the latest research on the role of TDP43 and microglia in neurodegeneration.

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  • Neuroinflammation is a defensive response, characterized by the activation of proinflammatory molecules including microglia and astrocytes. The response has been implicated in brain injuries, acute and chronic neurological and neurodegenerative disorders such as Alzheimer’s disease. Here is the latest research on neuroinflammation.
    Neuroinflammation

    Neuroinflammation is a defensive response, characterized by the activation of proinflammatory molecules including microglia and astrocytes. The response has been implicated in brain injuries, acute and chronic neurological and neurodegenerative disorders such as Alzheimer’s disease. Here is the latest research on neuroinflammation.

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  • This feed focuses on neuronal and network dysfunction in neurodegenerative disorders and the effects of tauopathies on synapses and memory.
    Neuronal and Network Dysfunction In Neurodegeneration

    This feed focuses on neuronal and network dysfunction in neurodegenerative disorders and the effects of tauopathies on synapses and memory.

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  • Prion diseases or transmissible spongiform encephalopathies are rare progressive neurogenerative diseases caused by misfolded prion proteins. Here is the latest research in this domain.
    Prion Disease
    Influential

    Prion diseases or transmissible spongiform encephalopathies are rare progressive neurogenerative diseases caused by misfolded prion proteins. Here is the latest research in this domain.

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  • Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion proteins, as an important biomarker of prion disease, are responsible for the transmissible spongiform encephalopathies. Here is the latest research investigating biomarkers in prion diseases.
    Prion Diseases: Biomarkers

    Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion proteins, as an important biomarker of prion disease, are responsible for the transmissible spongiform encephalopathies. Here is the latest research investigating biomarkers in prion diseases.

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  • Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Distinct prion strains are associated with different prion protein conformations and glycosylation patterns and associate with disease progression and severity. Here is the latest research on strain diversity and neurotoxicity in prion diseases.
    Prion Diseases: strain diversity and neurotoxicity

    Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Distinct prion strains are associated with different prion protein conformations and glycosylation patterns and associate with disease progression and severity. Here is the latest research on strain diversity and neurotoxicity in prion diseases.

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  • Prion diseases are fatal, transmissible, neurodegenerative diseases caused by the misfolding of the prion protein (prp). Here is the latest research on prion diseases.
    Prion Neurodegeneration
    Influential

    Prion diseases are fatal, transmissible, neurodegenerative diseases caused by the misfolding of the prion protein (prp). Here is the latest research on prion diseases.

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  • This feed focuses on the contribution of aging-associated proteotoxicity to inflammation and neurodegenerative disorders, including Alzheimer’s and dementia. Discover the latest research here.
    Proteotoxicity to Inflammation & Dementia
    Fast Growing

    This feed focuses on the contribution of aging-associated proteotoxicity to inflammation and neurodegenerative disorders, including Alzheimer’s and dementia. Discover the latest research here.

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  • Tau mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17) are associated with changes in alternative RNA splicing. Here is the latest research on RNA & Tau in Frontotemporal Dementia.
    RNA & Tau in Frontotemporal Dementia
    Influential

    Tau mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17) are associated with changes in alternative RNA splicing. Here is the latest research on RNA & Tau in Frontotemporal Dementia.

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  • Risk factors for neurodegeneration include trauma, lifestyle, and allelic variants of disease-associated genes with incomplete penetrance. Here is the latest research.
    Risk Factors for Neurodegeneration
    Fast Growing

    Risk factors for neurodegeneration include trauma, lifestyle, and allelic variants of disease-associated genes with incomplete penetrance. Here is the latest research.

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  • Tau and alpha-synuclein are proteins that form aggregates which characterize various neurodegenerative disorders including Parkinson’s disease. This feed focuses on the reaction of T lymphocytes in response to tau and alpha-synuclein.
    T Cell Reactivity to Tau & Alpha-Synuclein in PD

    Tau and alpha-synuclein are proteins that form aggregates which characterize various neurodegenerative disorders including Parkinson’s disease. This feed focuses on the reaction of T lymphocytes in response to tau and alpha-synuclein.

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  • TAR DNA binding protein (TDP43) is a DNA and RNA binding protein that is implicated in several neurodegenerative disorders known as “TDP43 proteinopathies" including Alzheimer's disease, amyotrophic lateral sclerosis and frontotemporal lobe dementia. Here is the latest research.
    TDP-43 Proteinopathies
    Fast Growing

    TAR DNA binding protein (TDP43) is a DNA and RNA binding protein that is implicated in several neurodegenerative disorders known as “TDP43 proteinopathies" including Alzheimer's disease, amyotrophic lateral sclerosis and frontotemporal lobe dementia. Here is the latest research.

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  • Tau Aggregation is an important characteristic in some neurodegenerative disorders, including Alzheimer’s Disease. Discover the latest research using genomics to understand Tau Aggregation.
    Tau Aggregation: Genomics

    Tau Aggregation is an important characteristic in some neurodegenerative disorders, including Alzheimer’s Disease. Discover the latest research using genomics to understand Tau Aggregation.

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  • Tau vaccination and administration of anti-tau antibodies can prevent pathology and cognitive impairment in transgenic mouse models of tauopathy, suggesting that therapies which increase anti-tau antibodies might slow the development and/or progression of tauopathies including Alzheimer's disease. Here is the latest research.
    Tau Antibody Therapy in Neurodegenerative Diseases

    Tau vaccination and administration of anti-tau antibodies can prevent pathology and cognitive impairment in transgenic mouse models of tauopathy, suggesting that therapies which increase anti-tau antibodies might slow the development and/or progression of tauopathies including Alzheimer's disease. Here is the latest research.

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  • Tau toxicity has been implicated in the emergence of synaptic dysfunction in Alzheimer's disease. Here is the latest research on Tau Toxicity in the Synapses.
    Tau Toxicity in the Synapses
    Influential

    Tau toxicity has been implicated in the emergence of synaptic dysfunction in Alzheimer's disease. Here is the latest research on Tau Toxicity in the Synapses.

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  • Tauopathies are neurodegenerative disorders caused due to misfolding and aggregation of the tau protein in neurofibrillary tangles in the brain. Discover the latest research on tauopathies here.
    Tauopathies

    Tauopathies are neurodegenerative disorders caused due to misfolding and aggregation of the tau protein in neurofibrillary tangles in the brain. Discover the latest research on tauopathies here.

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  • Tauopathies are neurodegenerative disorders that are caused due to the accumulation of abnormal tau proteins in neurons and/or the glia. Here is the latest research on tauopathy biochemistry.
    Tauopathy Biochemistry

    Tauopathies are neurodegenerative disorders that are caused due to the accumulation of abnormal tau proteins in neurons and/or the glia. Here is the latest research on tauopathy biochemistry.

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  • Vascular Dementia refers to the decline in thinking ability caused by cerebrovascular diseases. Discover the latest research on aspects underlying vascular dementia here.
    Vascular Dementia

    Vascular Dementia refers to the decline in thinking ability caused by cerebrovascular diseases. Discover the latest research on aspects underlying vascular dementia here.

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