Hereditary Neoplastic Syndromes


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  • Adenomatous polyposis coli is a protein encoded by the APC gene and acts as a tumor suppressor. Discover the latest research on adenomatous polyposis coli here.
    Adenomatous Polyposis Coli

    Adenomatous polyposis coli is a protein encoded by the APC gene and acts as a tumor suppressor. Discover the latest research on adenomatous polyposis coli here.

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  • Multiple Hamartoma Syndrome, also known as Cowden disease, is a hereditary autosomal dominant condition associated with mutations in tumor suppressor PTEN. Here is the latest research.
    Hamartoma Syndrome, Multiple

    Multiple Hamartoma Syndrome, also known as Cowden disease, is a hereditary autosomal dominant condition associated with mutations in tumor suppressor PTEN. Here is the latest research.

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  • Hereditary breast and ovarian cancer due to mutations in the brca1 and brca2 genes is the most common cause of hereditary forms of both breast and ovarian cancer. Here are the latest discoveries pertaining to these cancers.
    Hereditary Breast & Ovarian Cancer

    Hereditary breast and ovarian cancer due to mutations in the brca1 and brca2 genes is the most common cause of hereditary forms of both breast and ovarian cancer. Here are the latest discoveries pertaining to these cancers.

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  • Hereditary cancer syndromes comprise 5% of all cancers and have an increased risk of early onset and of multiple or bilateral malignancies. Here is the latest research on hereditary cancer syndromes.
    Hereditary Cancer Syndromes
    Influential

    Hereditary cancer syndromes comprise 5% of all cancers and have an increased risk of early onset and of multiple or bilateral malignancies. Here is the latest research on hereditary cancer syndromes.

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  • Hereditary Nonpolyposis Colorectal Neoplasms are a type of inherited autosomal dominant colon cancer and is associated with mutations in mismatch repair genes. Discover the latest research on Hereditary Nonpolyposis Colorectal Neoplasms.
    Hereditary Nonpolyposis Colorectal Neoplasms
    Going Viral

    Hereditary Nonpolyposis Colorectal Neoplasms are a type of inherited autosomal dominant colon cancer and is associated with mutations in mismatch repair genes. Discover the latest research on Hereditary Nonpolyposis Colorectal Neoplasms.

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  • Li-Fraumeni Syndrome is a rare autosomal dominant syndrome caused by mutations in the tumor suppressor TP53 and characterized by mesenchymal and epithelial neoplasms and several sites. Here is the latest research.
    Li-Fraumeni Syndrome
    Going Viral

    Li-Fraumeni Syndrome is a rare autosomal dominant syndrome caused by mutations in the tumor suppressor TP53 and characterized by mesenchymal and epithelial neoplasms and several sites. Here is the latest research.

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  • Multiple Endocrine Neoplasia is a group of inherited autosomal dominant cancers that occur in multiple hormone producing grandular organs. Discover the latest research on Multiple Endocrine Neoplasia here.
    Multiple Endocrine Neoplasia

    Multiple Endocrine Neoplasia is a group of inherited autosomal dominant cancers that occur in multiple hormone producing grandular organs. Discover the latest research on Multiple Endocrine Neoplasia here.

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  • Neurofibromatosis is a genetic disorder that causes tumors to form in the central nervous system. While these tumors are typically benign, they can become malignant. Other complications of neurofibromatosis include hearing loss, learning impairment, vision loss, etc. Here is the latest research.
    Neurofibromatosis

    Neurofibromatosis is a genetic disorder that causes tumors to form in the central nervous system. While these tumors are typically benign, they can become malignant. Other complications of neurofibromatosis include hearing loss, learning impairment, vision loss, etc. Here is the latest research.

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  • Neurofibromatosis 1 (NF1), also known as von Recklinghausen disease, is an autosomal dominant condition caused by mutations in the NF1 gene. Here is the latest research.
    Neurofibromatosis 1

    Neurofibromatosis 1 (NF1), also known as von Recklinghausen disease, is an autosomal dominant condition caused by mutations in the NF1 gene. Here is the latest research.

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  • Neurofibromatosis 2 (NF2) is a severe autosomal dominant disorder characterized by the occurrence of bilateral vestibular schwannomas and other benign tumors of the nervous system. Here is the latest research.
    Neurofibromatosis 2

    Neurofibromatosis 2 (NF2) is a severe autosomal dominant disorder characterized by the occurrence of bilateral vestibular schwannomas and other benign tumors of the nervous system. Here is the latest research.

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  • Peutz–Jeghers syndrome (PJS) is an autosomal dominant genetic disorder characterized by benign gastrointestinal polyps and melanosis. Discover the latest research on PJS here.
    Peutz-Jeghers Syndrome

    Peutz–Jeghers syndrome (PJS) is an autosomal dominant genetic disorder characterized by benign gastrointestinal polyps and melanosis. Discover the latest research on PJS here.

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  • Tuberous Sclerosis (TSC) is an autosomal dominant genetic disorder caused by mutations in TSC1 or TSC2 tumor suppressor genes and characterized by the development of benign hamartomas in multiple organs. Here is the latest research.
    Tuberous Sclerosis

    Tuberous Sclerosis (TSC) is an autosomal dominant genetic disorder caused by mutations in TSC1 or TSC2 tumor suppressor genes and characterized by the development of benign hamartomas in multiple organs. Here is the latest research.

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  • Wilms’ tumor, also known as nephroblastoma, is a specific type of cancer that begins in the kidneys and primarily in children. This is the most common type of kidney cancer found in children. Treatment options provide good prognosis for this disease. Discover the latest research on Wilms’ tumor here.
    Wilms Tumor

    Wilms’ tumor, also known as nephroblastoma, is a specific type of cancer that begins in the kidneys and primarily in children. This is the most common type of kidney cancer found in children. Treatment options provide good prognosis for this disease. Discover the latest research on Wilms’ tumor here.

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