Large-Scale Data & Computational Analysis


27 Feeds
  • Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.
    Alignment-free Sequence Analysis Tools

    Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

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  • The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.
    Applications of Molecular Barcoding
    Fast Growing

    The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

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  • Biodiversity refers to the variety and variability of life on Earth. Biodiversity is typically a measure of variation at the genetic, species, and ecosystem level.Discover the latest research on biodiversity data here.
    Biodiversity Data
    Fast Growing

    Biodiversity refers to the variety and variability of life on Earth. Biodiversity is typically a measure of variation at the genetic, species, and ecosystem level.Discover the latest research on biodiversity data here.

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  • Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.
    Bioinformatics in Biomedicine

    Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.

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  • Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) is a genome-wide technique used to map histone marks and protein binding (ie transcription factors) on chromatin. This can reveal insight into the regulation and dynamics of gene expression. Discover the latest research on ChIP-seq here.
    ChIP-Seq

    Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) is a genome-wide technique used to map histone marks and protein binding (ie transcription factors) on chromatin. This can reveal insight into the regulation and dynamics of gene expression. Discover the latest research on ChIP-seq here.

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  • Inter/Intra-Species: Comparative Sequencing describes the sequencing techniques that compare between and within species genomes. Discover the latest research on comparative sequencing of inter/intra-species here.
    Comparative Sequencing
    Fast Growing

    Inter/Intra-Species: Comparative Sequencing describes the sequencing techniques that compare between and within species genomes. Discover the latest research on comparative sequencing of inter/intra-species here.

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  • Computational benchmarking studies aim to rigorously compare the performance of different bioinformatic methods using well-characterized datasets. Discover the latest research on Benchmarking Computational Methods here.
    Computational Benchmarking Methods

    Computational benchmarking studies aim to rigorously compare the performance of different bioinformatic methods using well-characterized datasets. Discover the latest research on Benchmarking Computational Methods here.

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  • Computational pathology is an approach to diagnosis that incorporates multiple sources of data (e.g., pathology, radiology, clinical, molecular and lab operations); uses mathematical models to generate diagnostic inferences; and presents clinically actionable knowledge to customers.  This vision goes beyond an informatics-centric view and leverages the core competency of pathology and the ability to effectively communicate clinically actionable knowledge. Discover the latest research on computational pahtology here.
    Computational Pathology

    Computational pathology is an approach to diagnosis that incorporates multiple sources of data (e.g., pathology, radiology, clinical, molecular and lab operations); uses mathematical models to generate diagnostic inferences; and presents clinically actionable knowledge to customers. This vision goes beyond an informatics-centric view and leverages the core competency of pathology and the ability to effectively communicate clinically actionable knowledge. Discover the latest research on computational pahtology here.

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  • Managing and storing research data in formats that can be easily retrieved and shared, and publishing a variety of data outputs, including source data, improves reproducibility of research. Find the latest insights on data sharing here.
    Data Publishing & Management

    Managing and storing research data in formats that can be easily retrieved and shared, and publishing a variety of data outputs, including source data, improves reproducibility of research. Find the latest insights on data sharing here.

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  • Expression Quantitative Trait Loci (eQTL) analysis is the identification of specific or groups of genetic variants that affect gene expression levels within the cell. Discover the latest research on Expression Quantitative Trait Loci Analysis here.
    Expression Quantitative Trait Loci Analysis

    Expression Quantitative Trait Loci (eQTL) analysis is the identification of specific or groups of genetic variants that affect gene expression levels within the cell. Discover the latest research on Expression Quantitative Trait Loci Analysis here.

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  • Genetic epidemiology examines the role of genetic factors in determining health and disease in populations and the interaction between these genetic factors with environmental factors. Here is the latest research on the genetic epidemiology of complex multifactorial diseases like cancer.
    Genetic Epidemiology Of Complex Diseases

    Genetic epidemiology examines the role of genetic factors in determining health and disease in populations and the interaction between these genetic factors with environmental factors. Here is the latest research on the genetic epidemiology of complex multifactorial diseases like cancer.

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  • Genome annotation is the process of identifying genes and assigning function to each gene in a genome sequence. It provides the means to elucidate biological function from sequence. Here is the latest research.
    Genome Annotation

    Genome annotation is the process of identifying genes and assigning function to each gene in a genome sequence. It provides the means to elucidate biological function from sequence. Here is the latest research.

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  • Recent advances in next-generation sequencing have enabled faster and more accurate haplotyping methods to detect variants across a chromosome. Discover the latest research on Haplotyping here.
    Haplotyping
    Fast Growing

    Recent advances in next-generation sequencing have enabled faster and more accurate haplotyping methods to detect variants across a chromosome. Discover the latest research on Haplotyping here.

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  • The human microbiome refers to the collection of genomes of all the microorganisms inside the human body and on the surface. Discover the latest research on the human microbiome here.
    Human Microbiome
    Fast Growing

    The human microbiome refers to the collection of genomes of all the microorganisms inside the human body and on the surface. Discover the latest research on the human microbiome here.

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  • The Human Tumor Atlas is a collaborative project that uses detailed maps of a variety of cancers to investigate cancer development, metastasis, and treatments.
    Human Tumor Atlas
    Fast Growing

    The Human Tumor Atlas is a collaborative project that uses detailed maps of a variety of cancers to investigate cancer development, metastasis, and treatments.

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  • Lipidomics is a branch of metabolomics that comprehensively analyses lipids in biological systems to determine the molecules with which they interact and their function within the cell. Here is the latest research.
    Lipidomics

    Lipidomics is a branch of metabolomics that comprehensively analyses lipids in biological systems to determine the molecules with which they interact and their function within the cell. Here is the latest research.

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  • Metabolic flux analysis is an important method for the quantitative estimation of intracellular metabolic flows through metabolic pathways and the elucidation of cellular physiology. Here is the latest research.
    Metabolic Flux Analysis

    Metabolic flux analysis is an important method for the quantitative estimation of intracellular metabolic flows through metabolic pathways and the elucidation of cellular physiology. Here is the latest research.

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  • Metabolomics refers to the large-scale study of profiling all metabolites in biological systems in a non-targeted manner. Here is the latest research.
    Metabolomics

    Metabolomics refers to the large-scale study of profiling all metabolites in biological systems in a non-targeted manner. Here is the latest research.

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  • The human microbiota is composed of all microorganisms that reside inside and on the human body. This feed focuses on the collective genomes of all these microorganisms. Here is the latest research.
    Microbiome & Human Microbiota
    Fast Growing

    The human microbiota is composed of all microorganisms that reside inside and on the human body. This feed focuses on the collective genomes of all these microorganisms. Here is the latest research.

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  • Nanopore sequencing is a third generation pproach used in the sequencing of biopolymers- specifically, polynucleotides in the form of DNA or RNA. Discover the latest research on nanopore sequencing.
    Nanopore Sequencing
    Fast Growing

    Nanopore sequencing is a third generation pproach used in the sequencing of biopolymers- specifically, polynucleotides in the form of DNA or RNA. Discover the latest research on nanopore sequencing.

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  • Here is the latest research on scientific methods, processes, algorithms, and systems pertaining to the nervous system.
    Neural Data Science

    Here is the latest research on scientific methods, processes, algorithms, and systems pertaining to the nervous system.

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  • Precision medicine is a medical model that proposes the customization of healthcare, with medical decisions, treatments, practices, or products being tailored to the patient traits and specific molecular features of disease processes. In this model, diagnostic testing is often employed for selecting appropriate and optimal therapies based on the context of a patient’s genetic content or other molecular or cellular analysis. Tools employed in precision medicine can include molecular diagnostics, imaging, and analytics
    Precision Medicine

    Precision medicine is a medical model that proposes the customization of healthcare, with medical decisions, treatments, practices, or products being tailored to the patient traits and specific molecular features of disease processes. In this model, diagnostic testing is often employed for selecting appropriate and optimal therapies based on the context of a patient’s genetic content or other molecular or cellular analysis. Tools employed in precision medicine can include molecular diagnostics, imaging, and analytics

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  • Protein function prediction methods are techniques that bioinformatics researchers use to assign biological or biochemical roles to proteins. Discover the latest research on protein function prediction here.
    Protein Function Prediction
    Influential

    Protein function prediction methods are techniques that bioinformatics researchers use to assign biological or biochemical roles to proteins. Discover the latest research on protein function prediction here.

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  • Single cell sequencing (scs) can be harnessed to acquire the genomes, transcriptomes and epigenomes from individual cells. Here is the latest research on single cell sequencing.
    Single Cell Sequencing
    Fast Growing

    Single cell sequencing (scs) can be harnessed to acquire the genomes, transcriptomes and epigenomes from individual cells. Here is the latest research on single cell sequencing.

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  • Structural variations, such as insertions, deletions, inversions, and duplications, are a common feature in human genomes, and a number of studies have reported that such variations are associated with human diseases. Here is the latest research focusing on structural variation detection.

    Structural Variation Detection

    Structural variations, such as insertions, deletions, inversions, and duplications, are a common feature in human genomes, and a number of studies have reported that such variations are associated with human diseases. Here is the latest research focusing on structural variation detection.


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  • Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.
    Synthetic Genetic Array Analysis
    Fast Growing

    Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

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  • Despite advances in DNA sequencing technology, assembly of complex genomes remains a major challenge, particularly for genomes sequenced using short reads, which yield highly fragmented assemblies. Here is the latest research on de novo genome assembly.
    de novo Genome Assembly
    Fast Growing

    Despite advances in DNA sequencing technology, assembly of complex genomes remains a major challenge, particularly for genomes sequenced using short reads, which yield highly fragmented assemblies. Here is the latest research on de novo genome assembly.

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