Acute myeloid leukaemia (AML) is a common hematological type of cancer. As the population ages, there has been a rise in the frequency of AML. RNA expression has been used to see if there are different genetic profiles that exist within AML and whether these may underpin the variations in survival rates. Here is the latest research on AML and RNA.
Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous disease with approximately 20,000 cases per year in the United States. AML also accounts for 15-20% of all childhood acute leukemias, while it is responsible for more than half of the leukemic deaths in these patients. Here is the latest research on this disease.
Autoimmune lymphoproliferative syndrome (ALPS) is a rare genetic disorder of abnormal lymphocyte survival caused by defective Fas mediated apoptosis. Discover the latest research on ALPS here.
B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.
The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.
In CNS lymphoma, cancerous cells from lymph tissues or other parts of the body form tumors in the brain and/or spinal cord. Here is the latest research on this rare non-Hodgkin lymphoma.
Castleman disease is a rare disorder that involves an overgrowth of cells in the lymph nodes. Unicentric Castleman disease affects one lymph node, usually in the chest or abdomen. Multicentric Castleman disease affects multiple lymph nodes, commonly located in the neck, collarbone, underarm and groin areas. Discover the latest research on Castleman disease here.
Childhood vascular tumors are formed from cells related to blood vessels or lymph vessels. Here is the latest research on the genetics of childhood vascular tumors.
Chronic myelogenous leukemia (cml) is a clonal hematopoietic stem cell disorder characterized by the translocation and resultant production of the constitutively activated bcr-abl tyrosine kinase. Here is the latest research on this disease.
Composite Lymphoma involves different types of lymphoma cells concurrently. Here is the latest research on T-cell leukemia.
FMS related tyrosine kinase 3 (FLT3) is a frequently mutated receptor tyrosine kinase in Acute Myeloid Leukemia. Novel Tyrosine kinase inhibitors against FLT3 are currently in clinical trial. Discover the latest research on FLT3 Inhibitors in Acute Myeloid Leukemia here.
Follicular lymphoma is a slow-growing non-Hodgkin lymphoma involving B-lymphocytes. Here is the latest research on follicular lymphoma.
Hairy cell leukemia is a type of blood cancer involving the excess production of lymphocytes. Here is the latest research on hairy cell leukemia.
Hodgkin disease or Hodgkin's lymphoma is a type of lymphoma that affects the lymph system. Here is the latest research on Hodgkin disease.
Immunoblastic Lymphadenopathy is a disease where the lymph nodes are abnormally large and is characterized by both immunoblastic proliferation and small vessel proliferation. Discover the latest research on Immunoblastic Lymphadenopathy here.
Immunoglobulin Light-chain Amyloidosis is a disease characterized by excessive production of misfolded immunoglobulin light chains by plasma cells and leads to amyloid deposition. Discover the latest research on Immunoglobulin Light-chain Amyloidosis here.
Infectious Mononucleosis is a common disease caused by Epstein-Barr virus and is symptoms include fever, sore throat and swollen glands. Discover the latest research on Infectious Mononucleosis here.
B-cell leukemia includes various types of lymphoid leukemia that affect B cells. Here is the latest research on B-cell leukemia.
T-cell leukemia includes various types of lymphoid leukemia that affect T cells. Here is the latest research on T-cell leukemia.
Lymph nodes are part of the immune system and are spread throughout the body, draining lymph from various organs. Generating a spatial atlas of healthy human lymph nodes through single cell transcriptomics will gain insight into their complex biology. Discover the latest research on profiling human lymph nodes here.
Lymphoid neoplasms are derived from cells that frequently have features that recapitulate stages of normal b-, t-, and nk-cell differentiation and function. Lymphoid neoplasms include the following morphologic types: follicular center cell, lymphoblast (lymphocytic), immunoblast, plasma cell, and large granular lymphocyte (lgl). Here is the latest research on lymphoid neoplasms.
Mixed lineage leukemia-1 (MLL-1) is a particular type of acute leukemia from the mutation of the MLL/KMT2A gene. This mutation can be seen in pediatrics, adults and therapy-induced acute leukemia’s. Discover the latest research on MLL-r leukemia here.
Macrophage Activation Syndrome is a rare disorder in children and arises from abnormal activation and proliferation of T-cells and activation of macrophages. Discover the latest research on Macrophage Activation Syndrome here.
Mantle cell lymphoma is an aggressive B-cell non-Hodgkin lymphoma that develops around the lymph node's outer edge known as the mantle zone. Here is the latest research on mantle cell lymphoma.
Marek Disease is caused by an oncogenic herpesvirus and leads to lymphoproliferative disease in chickens. Discover the latest research in Marek Disease here.
Multiple myeloma is a cancer of the plasma cells, which normally is involved in antibody production. Discover the latest research on Multiple myeloma here.
Myelodysplastic syndromes are cancers in which immature blood cells in the bone marrow do not mature to become healthy blood cells. Discover the latest research on this cancer here.
MDSC (myeloid-derived suppressor cells) are a heterogenous group of immune cells from the myeloid lineage. MDSCs strongly expand in pathological situations such as chronic infections and cancer, as a result of an altered haematopoiesis. MDSCs are discriminated from other myeloid cell types in which they possess strong immunosuppressive activities rather than immunostimulatory properties.
Preleukemia refers to a hemic and lymphatic disease in which the bone marrow does not produce enough blood cells. Here is the latest research.
T-cell lymphoma are a group of lymphoid tumors in which T-lymphocytes undergo malignant transformations. Here is the latest research on T-cell lymphomas.