Medical Applications & Diagnosis
Antianginal drugs, including nitrates, beta-blockers, and calcium channel blockers, are used in the treatment of angina pectoris. Here is the latest research on their use and their mechanism of action.
Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.
Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.
Total artificial hearts (TAH) and ventricular assist devices (VADs) provide cardiac support for patients with end-stage heart disease and have significantly improved the survival of these patients. Discover the latest research on Artificial Heart and Ventricular Assist Devices here.
Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.
Cardiac electrophysiology is the study of electrical activities of the heart and includes the assessment, diagnosis, and treatment of cardiac events. Find the latest research on cardiac electrophysiology here.
Cardiac glycosides are a diverse family of naturally derived compounds that bind to and inhibit na+/k+-atpase. Discover the latest research on cardiac glycosides heres.
Cardiac organoids are 3D organ-like structures that can be derived from patients with cardiovascular diseases and are important disease models for drug discovery. Discover the latest research on Cardiac Organoids here.
Clinical lipidology focuses on diagnosis, pathophysiology, and clinical management of lipid and lipoprotein disorders. Here is the latest research.
This feed focuses on developing and applying computational algorithms for cardiac modeling and modeling of the cardiovasculature. Here is the latest research.
Electroencephalography (EEG) is an electrophysiological technique used to record electrical activity in the brain. It is commonly used in the diagnosis of epilepsy, sleep disorders, coma, encephalopathies, and brain death. Find the latest research on EEG here.
Physiological fluid dynamics can assist in understanding the pathological mechanisms. Understanding of cardiovascular diseases, hemodynamics and the circulatory system can assist in designing engineering devices as potential therapeutic strategies. Here is the latest research on fluid dynamics and engineering devices.
Fluorescence in situ hybridization (FISH) is one of the major techniques used to detect of chromosomal aberrations. Here is the latest research.
Gene therapy is emerging as a potential strategy for the treatment of cardiovascular diseases, such as peripheral arterial disease, ischemic heart disease, restenosis after angioplasty, vascular bypass graft occlusion and transplant-associated coronary artery disease. Discover the latest research on gene therapy for cardiovascular diseases here.
Genome editing is a powerful tool to study specific mutations or genes involved in the development and progression of cardiovascular disease. Discover the latest research on Genome Editing in Cardiovascular Disease here.
Heart transplantation is a surgical means of replacing a recipient's heart with a healthier organ. Find the latest research in heart transplantation here.
Examining the genomics, transcriptomics, proteomics and metabolomics of the human vascular endothelial cells at the single cell level will help build a single cell atlas of human vascular endothelium, which would give a unique ID card for each cell type, a three-dimensional map of how cell types work together to form tissues and insights into how changes in the map underlie health and disease of the vascular endothelium from young to old age. Disocver the latest research on the single cell atlas of human vascular endothelial cell atlas here.
Genetic testing is an important and necessary aspect of the management of families with cardiac genetic conditions. Here is the lastest research.
Inotropic agents alter the force or energy of muscular contractions. Negatively inotropic agents weaken the force of muscular contractions. Positively inotropic agents increase the strength of muscular contraction. Inotropic agents are used in hospitalized patients with acute decompensated heart failure, with reduced left ventricular ejection fraction and with signs of end-organ dysfunction in the setting of a low cardiac output, or with severe systolic heart failure awaiting heart transplant to maintain hemodynamic stability or as a bridge to decision. Discover the latest research on inotrpic agents and heart diseases here.
Establishing cardiomyocytes derived from human induced pluripotent stem cells has great potential as a cell source for therapeutic applications, such as regenerative medicine. Discover the latest research on Molecular Drivers of Cardiomyocyte Maturation here.
Prion diseases are fatal neurodegenerative and infectious disorders characterized by structural transition of the host-encoded cellular prion protein into the aberrantly folded pathologic isoform of the protein. Here is the latest research on molecular diagnostic strategies for prion diseases.
Multiple Sclerosis (MS) is a demyelinating autoimmune disease of the CNS, resulting in symptoms including optic neuritis and motor weakness. Here is the latest research on development and application of methods for diagnosis of MS.
Neuroimaging is a useful tool for studying brain function as well as for diagnosis of diseases and injuries to the brain. Follow this feed to stay up to date.
Parkinson’s disease is a progressive neurodegenerative disorder that affects movement. This feed focuses on genomic and drug-response biomarkers in Parkinson’s disease.
Parkinson’s disease (PD) is a neurodegenerative disorder that affects movement. This feed focuses on therapeutic aspects, diagnostic tools including medical imaging, and clinical trials in PD.
Precision medicine is a medical model that proposes the customization of healthcare, with medical decisions, treatments, practices, or products being tailored to the patient traits and specific molecular features of disease processes. In this model, diagnostic testing is often employed for selecting appropriate and optimal therapies based on the context of a patient’s genetic content or other molecular or cellular analysis. Tools employed in precision medicine can include molecular diagnostics, imaging, and analytics
Precision oncology is a new approach to cancer treatment, which utilizes the molecular profiling of each tumor to develop and tailor treatment strategies to each patient. The use of these biomarkers from tumors will help to predict those who will respond to specific treatments. Here is the latest research on precision oncology.
Prenatal diagnosis has enabled the detection of chromosomal abnormalities as well as single gene disorders and led to substantive improvements in the detection of congenital anomalies. Here is the latest research.
Proteomics is aimed at identifying and characterizing these protein changes and can be applied to the field of cardiovascular sciences, it has the potential to reveal those proteins that are associated with pathogenesis and could be potentially used as predictive or prognostic markers. Here is the latest research.
Quantitative fluorescence (QF)-PCR is a rapid molecular method that test for common chromosomal aneuploidies in prenatal diagnosis. Here is the latest research.
Right axis deviation is detected from the direction of electrical depolarisation on an electrocardiogram. This is an indication of some underlying pathological mechanism such as right bundle branch block, rhythm abnormality and lateral myocardial infarction. Here is the latest research on right axis deviation.
The vascular system is complex and comprised of various different cells types. This feed focuses on articles examining the human vasculature at the single cell level. Here is the latest research.
Combining genomic, transcriptomic, proteomic, and metabolomic data from the human heart at the single cell level will result in a single cell atlas of heart. This three-dimensional map of how cell types work together to form tissues will provide insights into how cellular functioning underlies health and disease of the heart. Disocver the latest research on the single cell atlas of the human heart here.
Statins or HMG-CoA reductase inhibitors, are used clinically to lower cholesterol levels and have been associated with decreased risk of heart disease. Discover the latest research on Statin Medications & Heart Disease here.
Stem cells have the therapeutic potential for cardiac repair and regeneration after myocardial infarction. Discover the latest research in Stem Cells In Cardiac Repair here.
Autophagy is an important pathway for breaking down proteins and damaged organelles and may play an important role in reducing cardiovascular diseases. Discover the latest research on Targeting Autophagy in Cardiovascular Disease here.
Vascular imaging makes it possible to quantify the number and spacing of blood vessels, measure blood flow and vascular permeability, and analyze cellular and molecular abnormalities in blood vessel walls. Discover the latest research on vascular imaging here.
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression through inhibition of protein translation or by degradation of specific transcripts. miRNAs can regulate cardiovascular health, and be potential biomarkers or targets in cardiovascular disease. Discover the latest research on miRNAs in Cardiovascular Biology here.
Non-coding RNAs (ncRNAs) are RNA molecules that do not code for protein, but can have functional roles in regulating gene expression at the transcriptional and post-transcriptional level. Discover the latest research on the role of ncRNAs in Health and Disease.