Bacterial transport proteins facilitate active and passive transport of small molecules and solutes across the bacterial membrane. Here is the latest research.
The blood brain barrier is a border that separates blood from cerebrospinal fluid. Discover the latest search on this highly selective semipermeable membrane here.
The blood brain barrier (BBB) is comprised of endothelial cells that regulate the influx and outflux of plasma concentrations. Lab-on-a-chip devices allow scientists to model diseases and mechanisms such as the passage of therapeutic antibodies across the BBB. Discover the latest research on BBB chips here.
Caveolins are small proteins with a hairpin loop conformation that are located in the plasma membrane of various cell types where they bind cholesterol and interact with receptors essential for several signal transduction pathways. Here is the latest research.
Membrane trafficking is the process through which macromolecules and other cargo are distributed throughout cell, released from the cell, or taken into the cell from extracellular space. Here is the latest research on mechanisms that regulate membrane trafficking.
This feed focuses on cytochromes, including cytochrome C and the cytochromes P450 (CYP) enzyme system, and their involvement in the activation and inactivation of drugs.
The electron transport chain (ETC) facilitates the transfer of electrons through redox while transferring protons across the membrane into the intermembrane space. This feed focuses on the structure and mechanism of the ETC as well as mitochondrial disorders caused by defects in the oxidative phosphorylation pathway.
Multiprotein adhesion structures allow the interaction of a cell with the extracellular matrix comprised of extracellular molecules that ensure tissue integrity and play a role in cell growth, migration, and differentiation. Here is the latest research.
The extracellular matrix (ECM) ensures tissue integrity and play a role in cell growth, migration, and differentiation. ECM turnover, therefore, is essential for tissue maintenance. Here is the latest research on mechanisms that regulate ECM turnover.
The extracellular matrix (ECM) ensures tissue integrity and play a role in cell growth, migration, and differentiation. ECM abnormalities play a key role in tumorigenesis and metastasis. Here is the latest research on ECM in cancer.
G-protein-coupled receptors (GPCRs), the largest family of integral membrane proteins, participate in the regulation of many physiological functions and are the targets of approximately 30% of currently marketed drugs. Here is the latest research.
GPCRs are membrane receptors implicated in the pathophysiology of various diseases. Several GPCRs, including GLP-1 receptor, glucagon receptor, and adiponectin receptor, are also involved in metabolic regulation and homeostasis. Here is the latest research.
G-protein coupled receptors (GPCRs) are membrane receptors implicated in the pathophysiology of various diseases, including neurodegenerative disorders, infectious diseases, and cancer. Here is the latest research on GPCR signaling pathway.
Gangliosides are sialic acid-containing glycosphingolipids concentrated on cell surfaces and found in abundance in the nervous system. Gangliosides have several functions, including a role in cholesterol absorption. Here is the latest research.
Interfacial lipids are key regulators of membrane-protein association and play a role in stabilizing membrane proteins. Here is the latest research.
Ion channels are pore-forming proteins that allow the passage of ions from one side of the membrane to the other and are at the heart of many biological processes including nerve activity and muscle contraction. Discover the latest research on ion channels here.
Lipopolysaccharides (LPS), also known as lipoglycans and endotoxins, are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a covalent bond. These are found in the outer membrane of gram-negative bacteria. Here is the latest research on LPS biogenesis.
Membrane and voltage-sensing domains describes the voltage-sensing domains of transmembrane proteins found in the cellular wall. Discover the latest research on membrane and voltage-sensing domains here.
Membrane Biophysics describes the study of membrane using various biophysical techiniques such as imaging, computational modeling, etc. Discover the latest research on membrane biophysics.
This feed focuses on biochemical techniques used for isolating and purifying membrane proteins from cells. Discover the latest research on Membrane Protein Extraction here.
Membrane proteins are found on cellular and intracellular membranes, and play important roles such as signal transduction, transport and enzymatic functions. Discover the latest research on the structure and function of membrane proteins here.
This feed focuses on Membrane Transport proteins and their dysfunction which can lead to heart disease. Discover the latest research on Membrane Transport in Heart Failure.
The Prion Disease: Cholesterol feed describes the role cholesterol plays in the conversion and transmission of prion. Discover the latest research on the role of cholesterol in prion disease here.