Astrocytes are abundant within the central nervous system and their dysfunction has been thought to be an important contributor to some neurodegenerative diseases, in particular Huntington’s disease. Damage to these cells may make neurons more susceptible to degeneration. Here is the latest research on astrocytes and Huntington’s disease.
Astrocytes are important for the health and function of the central nervous system. When these cells stop functioning properly, either through gain of function or loss of homeostatic controls, neurodegenerative diseases can occur. Here is the latest research on astrocytes and neurodegeneration.
A common feature of autism spectrum disorder (ASD) is the impairment of motor control and learning, consistent with perturbation in cerebellar function. Find the latest research on ASD and motor learning here.
Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.
Batten Disease is a group of nervous system disorders known as neuronal ceroid lipofuscinosis. This feed focuses on neurobiological and neuropathological aspects of this disease.
Several mechanisms and neural circuits in the cortex enable organisms to move from one place to another. Discover the latest research on cortical control of locomotion here.
Corticobasal Degeneration (CBD) is a rare neurodegenerative disease of the cerebral cortex and the basal ganglia, and is characterized by movement disorders. Discover the latest research on CBD here.
Deep Brain Stimulation is a neurosurgical procedure that uses a neurostimulator to stimulate specific regions of the brain for treatment of movement disorders. Here is the latest research.
Genome surgery using CRISPR genomic techniques offer the potential to correct disease-causing mutations in many neuronal disorders. Here are the latest discoveries pertaining to genome surgery and neuronal disorders.
The gut microbiota has been implicated in neurodevelopment, neuroinflammatory responses, and neurological disorders. Here is the latest research on the role of the gut microbiota in movement disorders.
The innate immune system is a first line of defense against infection. Pathological states can occur if there is over activation of the innate immune system, particularly in the brain. The excessive activation of these cells can lead to inflammation and neurodegenerative diseases. Here is the latest research on innate immunity and neurodegeneration.
Parkinson’s disease (PD) is a progressive neurodegenerative disorder that affects movement. The drug Inosine is proposed to slow progression of this disease. Here is the latest research on Inosine in PD.
Interactomics is the intersection of bioinformatics and biology concerned with investigating the interaction and the consequences of these interactions between proteins in a cell. Here is the latest research on interactomic data in neurodegeneration.
Lewy Body Disease is associated with abnormal deposits of proteins like alpha-synuclein in the brain and causes a decline in mental abilities. Here is the latest research on this progressive neurological disorder.
This feed focuses on the impact of insulin resistance, caloric restriction, cytokine singling, and metabolism on dementia and neurodegenerative diseases.
Microglia are found throughout the brain and spinal cord and are the resident macrophages of the CNS. There have been investigations into the involvement of microglia in somatosensory sensory circuits within the spinal cord and associated diseases. Here is the latest research on microglia and spinal somatosensory circuits.
The motor cortex is associated with planning, control, and execution of voluntary movements. This feed focuses on bi-directional communication pathways between an external device and the motor cortex.
Movement disorders are a group of nervous system disorders that increase or decrease voluntary or involuntary movements. Here is the latest research on genetic and environmental factors, as well as mechanisms that underlie movement disorders.
Multiple System Atrophy is a rare neurodegenerative disorder which affects the body’s autonomic functions, including breathing and muscle control. Discover the latest research on Multiple System Atrophy here.
Neuromodulation refers to a physiological process in which a neuron uses chemical(s) to regulate a variety of neuronal populations. Discover the latest research on neuromodulation here.
Neuromuscular disorders result in impaired functioning of the muscles. Discover the latest research on these disorders, including Amyotrophic Lateral Sclerosis, and the underlying genetic aspects here.
This feed focuses on experimental systems, including cell and tissue-based therapies, as well as genomic and proteomic approaches, used to study neuromuscular disorders in vitro. Discover the latest research on neuromuscular disorders in vitro here.
Neuroregeneration is the growth or repair of neural cells and tissues following damage or injury. Discover the latest research on neuroregeneration here.
Parkinson's Disease is a progressive neurodegenerative disorder characterized by loss of muscle control, including trembling of the limbs and impaired balance. Here is the latest research on this disease.
Alpha-synuclein is an integral component of Lewy bodies which are comprised of protein clumps and are a pathological hallmark of Parkinson’s disease. Here is the latest research on alpha-synuclein and Parkinson's disease.
Parkinson’s disease is a progressive neurodegenerative disorder that affects movement. This feed focuses on Parkinson's disease research using animal models.
Parkinson’s disease is a neurodegenerative disease characterized by involuntary movement, decreased movement, rigidity, and abnormal walking and posture. Targeting markers in the earliest stages of the disease may mitigate its progression. This feed focuses on biomarkers for Parkinson’s disease.
Parkinson’s disease (PD) is a neurodegenerative disorder that affects movement. This feed focuses on therapeutic aspects, diagnostic tools including medical imaging, and clinical trials in PD.
Parkinson’s disease is a progressive neurodegenerative disorder that affects movement. This feed focuses on genetic screening approaches and genetic predispositions in Parkinson’s disease.
Parkinson’s disease (PD) is a neurodegenerative disorder that affects movement. This feed focuses on leucine-rich repeat kinase 2 (LRRK2) which is the most prominent genetic contributor to PD.
This feed describes latest advances in spinal cord regeneration research and potential nerve regeneration treatments after spinal cord injuries.
Stem cells have the potential to develop into many different types of cells in the body and may be useful as a therapy for several diseases including neurodegenerative diseases. Discover the latest research on stem cells and neurodegenerative diseases here.
As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at a much more rapid rate. A reduction in synaptic density has been observed in neurodegenerative disorders, including Multiple Sclerosis, providing a potential area to target for treatment. Here is the latest research on synapse loss in neurodegenerative disorders and as a potential therapeutic target.
Motor neurons innervate muscles as a part of the peripheral nervous system and are responsible for both autonomic and volitional movement. Find the latest research on transcription in motor neurons here.
Visual perception and visual mental imagery, the faculty whereby we can revisualise a visual item from memory, have often been regarded as cognitive functions subserved by common mechanisms. Here are the latest discoveries pertaining to visual perception.
Wallerian degeneration refers to axonal degeneration in response to nerve fiber damage, where the axon distal to the injury site degenerates. Here is the latest research on Wallerian degeneration.