Astrocytes are abundant within the central nervous system and their dysfunction has been thought to be an important contributor to some neurodegenerative diseases, in particular Huntington’s disease. Damage to these cells may make neurons more susceptible to degeneration. Here is the latest research on astrocytes and Huntington’s disease.
Astrocytes are important for the health and function of the central nervous system. When these cells stop functioning properly, either through gain of function or loss of homeostatic controls, neurodegenerative diseases can occur. Here is the latest research on astrocytes and neurodegeneration.
A common feature of autism spectrum disorder (ASD) is the impairment of motor control and learning, consistent with perturbation in cerebellar function. Find the latest research on ASD and motor learning here.
Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.
Batten Disease is a group of nervous system disorders known as neuronal ceroid lipfuscinosis. This feed focuses on neurobiological and neuropathological aspects of this disease. Discover more here.
There exist several mechanisms and neural circuits in the cortex that enable organisms to move from one place to another. Discover the latest research on cortical control of locomotion here.
Corticobasal Degeneration (CBD)is a rare, neurodegenerative disease of the cerebral cortex and the basal ganglia, characterized by movement disorders. Discover the latest research on CBD here.
Deep Brain Stimulation is a neurosurgical procedure that uses a neurostimulator to stimulate specific regions of the brain for treatment of movement disorders. Here is the latest research.
This feed focuses on the impact of insulin resistance, caloric restriction, cytokine singling, and metabolism on dementia and neurodegenerative diseases. Here is the latest research in this domain.
Genome surgery using CRISPR genomic techniques offer the potential to correct disease-causing mutations in many neuronal disorders. Here are the latest discoveries pertaining to genome surgery and neuronal disorders.
Gut microbiota has been implicated in neurodevelopment, neuroinflammatory responses, and neurological disorders. Here is the latest research on the role of gut microbiota in movement disorders.
The innate immune system is a first line of defense against infection. Pathological states can occur if there is over activation of the innate immune system, particularly in the. The excessive activation of these cells can lead to inflammation and neurodegenerative diseases. Here is the latest research on innate immunity and neurodegeneration.
Parkinson’s disease (PD) is a progressive neurodegenerative disorder that affects movement. Drug Inosine is proposed to slow progression of this disease. Here is the latest research on Inosine in PD.
Interactomics is the intersection of bioinformatics and biology concerned with investigating the interaction and the consequences of these interactions between proteins in a cell. Here is the latest research on interactomic data in neurodegeneration.
Lewy Body Disease, associated with abnormal deposits of proteins like alpha-synuclein in the brain, causes a decline in mental abilities. Here is the latest on this progressive neurological disorder.
Microglia are found throughout the brain and spinal cord and are the resident macrophages of the CNS. There have been investigations into the involvement of microglia in somatosensory sensory circuits within the spinal cord and associated diseases. Here is the latest research on microglia and spinal somatosensory circuits.
The motor cortex is associated with planning, control, and execution of voluntary movements. This feed focuses on bi-directional communication pathways between an external device and the motor cortex.
Movement disorders are a group of nervous system disorders that increase or decrease voluntary or involuntary movements. Here is the latest research on genetic and environmental factors, as well as mechanisms that underlie movement disorders.
Multiple System Atrophy (MSA) is a rare neurodegenerative disorder which affects the body’s autonomic functions, including breathing and muscle control. Discover the latest research on MSA here.
Neuromodulation refers to a physiological process in which a neuron uses chemical(s) to regulate a variety of neuronal populations. Discover the latest research on neuromodulation here.
Neuromuscular disorders result in impaired functioning of the muscles. Discover the latest research on these disorders, including ALS, and the underlying genetic aspects here.
This feed focuses on experimental systems, including cell and tissue-based therapies, as well as genomic and proteomic approaches, used to study neuromuscular disorders in vitro.
Neuroregeneration is the growth or repair of neural cells and tissues following damage or injury. Discover the latest research on neuroregeneration here.
Parkinson's Disease is a progressive neurodegenerative disorder characterized by loss of muscle control, including trembling of the limbs and impaired balance. Here is the latest research.
Alpha-synuclein is an integral component of Lewy bodies which are comprised of protein clumps and are a pathological hallmark of Parkinson’s disease. Here is the latest research.
Parkinson’s disease is a progressive neurodegenerative disorder that affects movement. This feed focuses on animal models used for Parkinson's disease research.
Parkinson’s disease is a progressive neurodegenerative disorder that affects movement. This feed focuses on genomic and drug-response biomarkers in Parkinson’s disease.
Parkinson’s disease (PD) is a neurodegenerative disorder that affects movement. This feed focuses on therapeutic aspects, diagnostic tools including medical imaging, and clinical trials in PD.
Parkinson’s disease is a progressive neurodegenerative disorder that affects movement. This feed focuses on genetic screening approaches and genetic predispositions in Parkinson’s disease.
Parkinson’s disease (PD) is a neurodegenerative disorder that affects movement. This feed focuses on leucine-rich repeat kinase 2 (LRRK2) which is the most prominent genetic contributor to PD.
This feed describes the advancement in spinal cord regeneration research and potential nerve regeneration treatments after spinal cord injuries.
Stem cells have the potential to develop into many different types of cells in the body and may be useful as a therapy for several diseases including neurodegenerative diseases. Discover the latest research on stem cells and neurodegenerative diseases here.
As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at a much more rapid rate. In MS it has been shown that there is a reduction in synaptic density, which is a potential area to target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.
Motor neurons innervate muscles as a part of the peripheral nervous system and are responsible for both autonomic and volitional movement. Find the latest research on transcription in motor neurons here.
Visual perception and visual mental imagery, the faculty whereby we can revisualise a visual item from memory, have often been regarded as cognitive functions subserved by common mechanisms. Here are the latest discoveries pertaining to visual perception.
Wallerian Degeneration refers to active degeneration of part of the axon distal to the injury in response to nerve fiber damage. Here is the latest research on aspects underlying this degeneration