African trypanosomiasis, also known as sleeping sickness, is an insect-borne parasitic disease of humans and other animals. It is caused by protozoa of the species Trypanosoma brucei and almost invariably progresses to death unless treated. Discover the latest research on African trypanosomiasis here.
Amoebiasis, infection by the protozoan parasite Entamoeba histolytica, remains a global health problem, despite the availability of effective treatment. Here is the latest research.
Ascariasis is a helminthic infection of global distribution with more than 1.4 billion persons infected throughout the world. Here is the latest research.
Babesiosis is caused by parasites of the genus babesia, which are transmitted in nature by the bite of an infected tick. Discover the latest research on babesiosis here.
Chagas disease, also known as American trypanosomiasis, is a tropical parasitic disease caused by the protist Trypanosoma cruzi. It is spread mostly by insects known as Triatominae, or "kissing bugs". The symptoms change over the course of the infection. In the early stage, symptoms are typically either not present or mild, and may include fever, swollen lymph nodes, headaches, or local swelling at the site of the bite. After 8–12 weeks, individuals enter the chronic phase of disease and in 60–70% it never produces further symptoms.The other 30–40% of people develop further symptoms 10–30 years after the initial infection, including enlargement of the ventricles of the heart in 20–30%, leading to heart failure. An enlarged esophagus or an enlarged colon may also occur in 10% of people. Discover the latest research on Chagas disease here.
Clonorchiasis is a food foodborne parasitic infection caused by the trematode Clonorchis sinensis and presents as liver disease. Find the latest research on clonorchiasis here.
CRISPR-Cas system enables the editing of genes to create or correct mutations. This technology is being investigated to combat malaria by targeting specific stretches of vector DNA and editing the genome at precise locations. Here is the latest research.
Cryptosporidiosis is a self-limited diarrheal disease that occurs in the community setting but can be chronic and potentially serious in immunocompromised patients. Here is the latest research.
Cysticercosis in humans results from infestation with the larval stage of the parasite cysticercus cellulosae of the tapeworm taenia solium. Discover the latest research on cysticercosis here.
Echinococcosis or hydatid disease in humans is a zoonotic infection caused by the larval stages of cestode species of the genus echinococcus. Discover the latest research on Echinococcosis here.
Fascioliasis is a zoonotic parasitic disease caused by fasciola hepatica and fasciola gigantica that primarily affects ruminants. Discover the latest research on Fascioliasis here.
Filariasis is a parasitic infection caused by various nematodes of the Filarioidea superfamily. Different worms present as different infections depending on the the location of thhe infection: lymphatic filariasis (caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori) is an infection of the lymphatic system, subcutaneous filariasis (caused by Loa loa, Mansonella streptocerca, and Onchocerca volvulus) is an infection of the skin, and serous cavity filariasis (Mansonella perstans and Mansonella ozzardi) is an abdominal infection. Find the latest research on filariasis here.
Giardia is caused by Giardia lamblia, a parasite that colonizes the small intestine and is transmitted via the fecal-oral route. Find the latest research on giardiasis here.
Hookworm infection is an infection by a type of intestinal parasite known as a hookworm. Discover the latest research on hookworm infection here.
Infectious Disease Sequencing is a emerging field due to low-cost massively parallel sequencing and allows researchers to monitor outbreaks of infectious pathogens. Discover the latest research on Infectious Disease Sequencing here.
Pyroptosis is a form of necrotic and inflammatory programmed cell death induced by inflammatory caspases, one of which is activated by Inflammasome, a multiprotein oligomer responsible for the activation of inflammatory responses. Discover the latest research on inflammasome and pyroptosis here.
Leishmaniasis is a parasitic infection caused by Leishmania species and transmitted though the bite of phlebotomine sand flies. It is considered to be a neglected tropical disease. Leishmaniasis is often categorized as cutaneous (presenting with skin sores, mucocutaneous (presenting with skin and mucosal lesions), and visceral (affecting multiple organs). Find the latest research on leishmaniasis here.
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. Discover the latest research on malaria here,
Research for development of a malaria vaccine is currently underway to find an effective modality to control and eliminate the transmission of malaria. To date, no vaccine has been found to be efficacious in fighting against malaria. Here is the latest research on malaria vaccines.
Onchocerciasis, also known as river blindness, is a disease caused by infection with the parasitic worm Onchocerca volvulus. Symptoms include severe itching, bumps under the skin, and blindness. It is the second-most common cause of blindness due to infection, after trachoma. Discover the latest research on onchocerciasis here.
Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.
Malaria remains a major cause of morbidity and mortality in the tropics, with the parasite Plasmodium falciparum responsible for the majority of the disease burden. Discover the latest research on Plasmodium falciparum.
Scabies is a parasitic skin disease specific to humans caused by a microscopic mite, sarcoptes scabiei var. Discover the latest research on scabies here.
Schistosomiasis is a parasitic infection that affects 200 million people and is directly responsible for an annual death of 20,000 patients. Here is the latest research.
Strongyloidiasis is a human parasitic disease caused by the nematode called Strongyloides stercoralis. It can occur without any symptoms or as a potentially fatal hyperinfection or disseminated infection. Discover the latest research on strongyloidiasis here.
Toxocariasis, caused by infection with larvae of Toxocara canis, and to a lesser extent by Toxocara cati and other ascaridoid species, manifests in humans in a range of clinical syndromes. Here is the latest research.
Toxoplasmosis, caused by the protozoan parasite toxoplasma gondii, is one of the most common parasitic infections. Here is the latest research.
Trichomoniasis is a sexually transmitted disease caused by the Trichomonas vaginalis parasite. Symptoms include irritation and inflammation. Discover the latest research on Trichomoniasis here.