Protein Chemistry & Proteomics
Key regulators of cell cycle, including cyclins, cyclin dependent kinase inhibitors, DNA replication factors, are controlled by proteolysis. Discover the latest research on cell cycle control and proteolysis.
Chemoproteomics is an approach to discovering mechanisms for regulating biological pathways for the purpose of designing new pharmaceutical therapies. Here is the latest research on this chemical proteomic method for pharmacological discovery research.
Investigating human cellular proteins through a combination of highly multiplexed imaging and proteomic analyses can help characterize all human cells at the proteomic level. Discover the latest research on deep visual proteomics here.
The transcriptome and proteome of the human male testis is being mapped to better understand its molecular functioning and disease pathology. Using methods such as mass spectrometry, FISH, and RNA sequencing, the human testis can be mapped successfully. Discover the latest research on mapping the transcriptome and proteome of the testis here.
This feed focuses on the use of proteomic and proteogenomic approaches in neurobiology and neurobiological disorders. Here is the latest research.
Protacs, which induce selective degradation of their target protein via the ubiquitin-proteasome system, are useful for the down-regulation of various proteins, including disease-related proteins and epigenetic proteins. Here is the latest research on protacs.
Phosphoproteomics refers to the identification and quantification of phosphorylated proteins in the proteome. This approach provides a high-throughput method of examining the state of intracellular phosphorylation. Here is the latest research on phosphoproteomics.
Protein metabolism refers to the various biochemical processes that occur resulting in protein anabolism or catabolism. Discover the latest research on protein metabolism in this feed.
Proteogenomics is a multi-omics research field that has the aim to efficiently integrate genomics, transcriptomics and proteomics. Here is the latest research on proteogenomics.
Proteolysis refers to the breakdown of proteins into amino acids or shorter polypeptides. Discover the latest research on mechanism that underlie proteolysis here.
Proteomics is aimed at identifying and characterizing these protein changes and can be applied to the field of cardiovascular sciences, it has the potential to reveal those proteins that are associated with pathogenesis and could be potentially used as predictive or prognostic markers. Here is the latest research.
Proteostasis enables the maintenance of protein homeostasis via modulation of protein translation, enhancement of chaperone capacity and the prompt clearance of misfolded proteins. It is affected in several neurodegenerative diseases. Here is the latest research.
Single cell transcriptomics enables the examination of gene expression at an individual cell level by measuring mRNA concentration of genes. Here is the latest research.
Ubiquitin is a small regulatory protein that is attached to proteins as a post-translational modification in a process known as ubiquitination to regulate protein turnover, location, or activity. Here is the latest research on the ubiquitin system.
tRNA modifications are partial or minor changes on tRNA that result in different version of the original tRNA. Discover the latest research on tRNA modification here.