Protein Manipulation & Analysis

Chemoproteomics is an approach to discovering mechanisms for regulating biological pathways for the purpose of designing new pharmaceutical therapies. Here is the latest research on this chemical proteomic method for pharmacological discovery research.

Investigating human cellular proteins through a combination of highly multiplexed imaging and proteomic analyses can help characterize all human cells at the proteomic level. Discover the latest research on deep visual proteomics here.

Imaging mass spectrometry enables the visualization and assessment of the spatial distribution of molecules, including biomarkers and metabolites, based on their molecular mass. Here is the latest research.

The transcriptome and proteome of the human male testis is being mapped to better understand its molecular functioning and disease pathology. Using methods such as mass spectrometry, FISH, and RNA sequencing, the human testis can be mapped successfully. Discover the latest research on mapping the transcriptome and proteome of the testis here.

This feed focuses on the use of proteomic and proteogenomic approaches in neurobiology and neurobiological disorders. Here is the latest research.

Protacs, which induce selective degradation of their target protein via the ubiquitin-proteasome system, are useful for the down-regulation of various proteins, including disease-related proteins and epigenetic proteins. Here is the latest research on protacs.

Phosphoproteomics refers to the identification and quantification of phosphorylated proteins in the proteome. This approach provides a high-throughput method of examining the state of intracellular phosphorylation. Here is the latest research on phosphoproteomics.

Proteogenomics is a multi-omics research field that has the aim to efficiently integrate genomics, transcriptomics and proteomics. Here is the latest research on proteogenomics.

Proteomics is aimed at identifying and characterizing these protein changes and can be applied to the field of cardiovascular sciences, it has the potential to reveal those proteins that are associated with pathogenesis and could be potentially used as predictive or prognostic markers. Here is the latest research.

Structure-based drug design (sbdd) combines the power of many scientific disciplines, such as x-ray crystallography, nuclear magnetic resonance, medicinal chemistry, molecular modeling, biology, enzymology and biochemistry, in a functional paradigm of drug development. Here is the latest research on sbdd.