Acute viral rhinopharyngitis, also known as "common cold", is an acute, self-limiting viral infection of the upper respiratory tract involving the nose, sinuses, pharynx and larynx. Discover the latest research on acute viral rhinopharyngitis here.
Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.
Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.
Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.
A growing number of complications associated with COVID-19 has been identified. This feed focuses primarily on cardiovascular and respiratory manifestations in severely ill patients.
Understanding the innate and acquired immune response to SARS-CoV-2 is essential for development of COVID-19 therapeutic treatment and design of prophylactic vaccines. This feed surfaces immunological studies, including studies into the cytokine storm that has been observed in severely ill patients.
The research highlighted in this feed investigates the immunopathology seen in severely ill COVID-19 patients, which often resembles the cytokine storm syndrome: uncontrolled immune activation generates excessive release of cytokines, resulting in hyperinflammation and multi-organ disease.
COVID-19 patients frequently have neurological symptoms, which are probably caused by the virus invading the central nervous system. Symptoms range from a loss of smell and taste to serious complications such as encephalitis, many of which are associated with poor prognosis. This feed follows the latest developments and research into the neurological complications associated with COVID-19.
Factors associated with COVID-19 patient admissions to Intensive Care Units and with death include older age, comorbid conditions, obesity. Ethnic minority backgrounds and genetics, as well as economic inequalities are also likely to play a role in disease outcomes. A variety of COVID-19 risk factors are explored in the publications followed in this feed.
A SARS-CoV-2 vaccine would be a very powerful tool to slow down the COVID-19 pandemic. Well over a hundred vaccine candidates are in development, with some already being tested for safety and efficacy, or in phase I clinical trials. This feed follows the latest studies on vaccine design and development.
Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.
The entry of coronaviruses into susceptible host cells is mediated by the viral S (Spike) glycoprotein. This feed covers latest findings about this complex process and the ongoing research efforts into finding therapeutics that can target the viral Spike protein and hence disrupt virus-cell fusion.
Deciphering and comparing the proteins of different coronaviruses forms a basis for understanding SARS-CoV-2 evolution and virus-receptor interactions. This feed follows studies analyzing the structures of coronavirus proteins, thereby revealing potential drug target sites.
Diphtheria is a bacterial infection caused by Corynebacterium diphtheriae. Transmission is usually airborne, and the disease usually presents with respiratory symptoms including sore throat and cough, but can involve complications such as myocarditis or neuritis. Find the latest research on diphtheria here.
Infectious Disease Sequencing is a emerging field due to low-cost massively parallel sequencing and allows researchers to monitor outbreaks of infectious pathogens. Discover the latest research on Infectious Disease Sequencing here.
Influenza, commonly known as the flu, is an infectious disease caused by an influenza virus.Symptoms can be mild to severe. The most common symptoms include: high fever, runny nose, sore throat, muscle pains, headache, coughing, sneezing, and feeling tired. Discover the latest research on influenza here.
Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria Mycobacterium leprae or Mycobacterium lepromatosis. Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. This damage may result in a lack of ability to feel pain, which can lead to the loss of parts of extremities from repeated injuries or infection due to unnoticed wounds. Discover the latest research on leprosy here.
Leptospirosis is an infection caused by corkscrew-shaped bacteria called Leptospira.Signs and symptoms can range from none to mild such as headaches, muscle pains, and fevers to severe with bleeding from the lungs or meningitis. If the infection causes the person to turn yellow, have kidney failure and bleeding, it is then known as Weil's disease.If it also causes bleeding into the lungs then it is known as severe pulmonary haemorrhage syndrome. Discover the latest research on leptospirosis here.
Human metapneumovirus infection is a leading cause of respiratory tract infection in the first years of life, with a spectrum of disease similar to that of respiratory syncytial virus. Here is the latest research.
Middle East Respiratory Syndrome (MERS) coronavirus (MERS-CoV), a novel coronavirus that causes a severe lower respiratory tract infection in humans, emerged in the middle east in 2012. Here is the latest research.
Models that predict the course of the COVID-19 epidemic have been crucial in developing public health policies and continue to be used to plan effective control strategies. This feed surfaces papers reporting new models and modeling methods applied to COVID-19 data.
Nipah virus infection is an emerging zoonotic infection which presents with acute encephalitis and respiratory distress syndrome. Discover the latest research on Nipah Virus Infection here.
Pneumococcal infection is an infection caused by the bacterium Streptococcus pneumoniae, which is also called the pneumococcus.
Respiratory syncytial virus (RSV) is a respiratory illness in both children and adults. Discover the latest research on RSV here.
Like other coronaviruses, SARS-CoV-2 is evolving. The genomic diversity of SARS-CoV-2 strains in different countries is consistent with multiple introductions of the virus to different locations, seeding local transmission events. The papers in this feed report latest research into genetic variation and phylogeny of this highly successful virus.
The SARS-CoV-2 virus enters the human host cell via the receptor ACE2 and uses the serine protease TMPRSS2 for S protein priming. The ACE2 usage has been shown to be crucial for transmissibility of other coronaviruses. Much research into the COVID-19 pandemic focuses on understanding the complex process of virus entry.
Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the SARS coronavirus (SARS-CoV). Initial symptoms are flu-like and may include fever, muscle pain, lethargy symptoms, cough, sore throat, and other nonspecific symptoms. SARS may eventually lead to shortness of breath and pneumonia; either direct viral pneumonia or secondary bacterial pneumonia. DIscover the latest research on SARS here.
Tuberculosis is an infectious disease usually caused by Mycobacterium tuberculosis bacteria. Discover the latest research on tuberculosis here.
Viral respiratory tract infections can have profound effects on important aspects of asthma. Discover the latest research on viral infections and asthma here.
Viral pneumonias account for at least 17% of cases of community-acquired pneumonia in children and in adults. Here is the latest research.