Systemic Physiology

Cancer genomics employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest research here.

Cancer metabolic reprogramming is important for the rapid growth and proliferation of cancer cells. Cancer cells have the ability to change their metabolic demands depending on their environment, regulated by the activation of oncogenes or loss of tumor suppressor genes. Here is the latest research on cancer metabolic reprogramming.

Computational modeling and the theory of nonlinear dynamical systems allow one to not simply describe the events of the cell cycle, but also to understand why these events occur. Discover the latest research on cell cycle modeling here.

Inter/Intra-Species: Comparative Sequencing describes the sequencing techniques that compare between and within species genomes. Discover the latest research on comparative sequencing of inter/intra-species here.

Investigating human cellular proteins through a combination of highly multiplexed imaging and proteomic analyses can help characterize all human cells at the proteomic level. Discover the latest research on deep visual proteomics here.

Genetic circuits are essential for many biological processes including oscillation (e.g. the cell cycle), cell differentiation, patterning of multicellular tissues, and cellular response to environmental signals. Here is the latest research on editing these genetic circuits.

Glycomics, the study of glycans and glycan-binding proteins in various biological systems, is an emerging field in the postgenome and postproteomics era. Here is the latest research.

Gut microbiota composition has been implicated in neuroinflammatory responses, as well as brain aging and brain-aging related diseases like amyloid neuropathies. Here is the latest research.

Gut microbiota has been implicated in neurodevelopment, neuroinflammatory responses, and neurological disorders. Here is the latest research on the role of gut microbiota in movement disorders.

The feed focuses on the emerging role of Gut Microbiota, also known as the gastrointestinal microbiome, in Type 2 Diabetes. Deficiency in gut microbiota has been linked to type 2 diabetes.

Examining the genomics, transcriptomics, proteomics, and metabolomics of the human adipose tissues at the single cell level will help build a single cell atlas of these tissues, which would give a unique ID card for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease states in which adipose tissues are involved. Disocver the latest research on the human adipose tissue heterogeneity here.

Metabolic, protein-protein, and gene regulatory networks composed of physical and biochemical interactions between macromolecules are the three main types of interactome networks. Here is the latest research on these networks in cancer.

Interactomics is the intersection of bioinformatics and biology concerned with investigating the interaction and the consequences of these interactions between proteins in a cell. Here is the latest research on interactomic data in neurodegeneration.

Metabolomics refers to the large-scale study of profiling all metabolites in biological systems in a non-targeted manner. Here is the latest research.

This feed focuses on the use of proteomic and proteogenomic approaches in neurobiology and neurobiological disorders. Here is the latest research.

This feed focuses on experimental systems, including cell and tissue-based therapies, as well as genomic and proteomic approaches, used to study neuromuscular disorders in vitro.

Omics are used to understand the gene expression profile and proteomics of many diseases. This feed focuses on the omics of myocardial infarction and heart failure. Here are the latest discoveries pertaining to this disease.

This feed focuses on the identification of genomic, epigenetic, transcriptomic, and proteomic signatures in pancreatic cells and cells derived from diabetic patients. Here is the latest research.

Phosphoproteomics refers to the identification and quantification of phosphorylated proteins in the proteome. This approach provides a high-throughput method of examining the state of intracellular phosphorylation. Here is the latest research on phosphoproteomics.

Proteogenomics is a multi-omics research field that has the aim to efficiently integrate genomics, transcriptomics and proteomics. Here is the latest research on proteogenomics.

Proteomics is aimed at identifying and characterizing these protein changes and can be applied to the field of cardiovascular sciences, it has the potential to reveal those proteins that are associated with pathogenesis and could be potentially used as predictive or prognostic markers. Here is the latest research.