Antianginal drugs, including nitrates, beta-blockers, and calcium channel blockers, are used in the treatment of angina pectoris. Here is the latest research on their use and their mechanism of action.
Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.
Arterial-venous development may play a crucial role in cardiovascular diseases. Here is the latest research.
Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.
Coagulation is the process by which a blood clot is formed. This process includes both the formation of a platelet plug as well as a cascade of clotting factors resulting in the formation of fibrin strands. Find the latest research on coagulation signaling pathways here.
The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.
Cardiovascular regulation and homeostasis is important in maintaining health and dysfunction may lead to cardiovascular diseases. Nitric oxide and vascular endothelium are one of many molecules involved in the homeostatic mechanism. Here is the latest research on cardiovascular homeostasis.
Prevention of cardiovascular disease is an important health initiative. Risk reduction including physical activity, smoking cessation, diet, blood pressure lowering drugs and pharmacotherapy. Here is the latest research on cardiovascular risk reduction.
Cavernous hemangioma is a blood vessel defect or benign tumor that leads to leakage of blood to the surrounding tissues. This can occur in several organs including the brain, which can lead to seizures. Discover the latest research on cavernous hemangiomas here.
Cryoglobulinemia is a disease characterized by large immunoglobulin aggregates that precipitate at low body temperatures, termed cryoglobulins. Discover the latest research on cryoglobulinemia here.
Ehlers-Danlos syndrome is a group of heritable connective tissue disorders that have 13 different subtypes. Discover the latest research on Ehlers-Danos syndrome here.
Endothelial cells line the vasculature as a monolayer and play an important role in maintaining homeostasis. Find the latest research on endothelial cell biology here.
Hereditary Hemorrhagic Telangiectasia is an autosomal dominant genetic disorder characterized by abnormal blood vessel formation and bleeding in various tissues or organs. Discover the latest research on Hereditary Hemorrhagic Telangiectasia here.
Inflammation in the vasculature permits the migration of leukocytes through the vascular wall to resolve injury. However, unresolved inflammation is also pathogenic in such conditions as atherosclerosis, ischemia/reperfusion, or vasculitis. Find the latest research on inflammation of the vascular wall here.
Multiple Myeloma is a cancer of the plasma cells, which normally is involved in antibody production. Discover the latest research on Multiple Myeloma here.
Platelets are a blood cell that can initiate clot formation in response to damage to blood vessels. Following platelet adhesion, platelets become activated before aggregating. Find the latest research on platelet activation here.
Platelets are a blood cell that can initiate clot formation in response to damage to blood vessels. Disruption of the vascular endothelium exposes ligands the induce platelet adhesion, followed by platelet activation and aggregation. Find the latest research on platelet adhersion here.
Platelets are a blood cell that can initiate clot formation in response to damage to blood vessels. Find the latest research on platelet signaling here.
Pseudoxanthoma elasticum is a genetic disorder caued by mutations in the ATP-binding cassette sub-family C member 6 gene (ABCC6) and is characterized by lax skin and retinal hemorrhages. Discover the latest research on pseudoxanthoma elasticum here.
Angiogenesis is considered an important process in the development of malignancies that can be regulated through long non-coding RNAs (lncRNAs). Discover the latest research on Regulation of Angiogenesis by lncRNAs here.
Scurvy is a disease attributed with vitamin C deficiency and is characterized by gum disease, general weakness and tiredness, bleeding, poor wound healing, and low red blood cell count. Discover the latest research on scurvy here.
Thrombosis, the formation of a blood clot inside a blood vessel that obstructs the flow of blood through the circulatory system, is thought to occur when natural hemostatic mechanisms, which help restrict the clot to the site of injury, are genetically impaired or are overwhelmed by the severity of the initial injury. Discover the latest research on hemostasis and thrombosis here.
Vascular Endothelial Growth Factor B (VEGF-B) is growth factor related to VEGFA, but is not typically involved in blood vessel growth. Discover the latest research on VEGF-B & Angiogenesis here.
Vascular disease prevention is important to reduce the incidence of cardiovascular events and the high morbidity and mortality. Here is the latest research.
Vascular imaging makes it possible to quantify the number and spacing of blood vessels, measure blood flow and vascular permeability, and analyze cellular and molecular abnormalities in blood vessel walls. Discover the latest research on vascular imaging here.
Waldenstrom macroglobulinemia is a cancer that originates in B cells and is characterized by the overproduction of macroglobulins. Symptoms include vision impairment, bleeding, and nervous system problems. Discover the latest research on Waldenstrom macroglobulinemia here.