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Acute Myeloid Leukaemia & RNA

Acute Myeloid Leukaemia & RNA diagram by undefined

Acute myeloid leukaemia (AML) is a common hematological type of cancer. As the population ages, there has been a rise in the frequency of AML. RNA expression has been used to see if there are different genetic profiles that exist within AML and whether these may underpin the variations in survival rates. Here is the latest research on AML and RNA.

Top 20 most recent papers
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

Valproate and Retinoic Acid in Combination With Decitabine in Elderly Nonfit Patients With Acute Myeloid Leukemia: Results of a Multicenter, Randomized, 2 × 2, Phase II Trial

Journal of Clinical Oncology : Official Journal of the American Society of Clinical OncologyDecember 3, 2019
Michael LübbertDECIDER Study Team
9
1
Nature Communications

The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

Nature CommunicationsNovember 25, 2019
Dimitrios PapaioannouRamiro Garzon
Nature Chemical Biology

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma

Nature Chemical BiologyDecember 9, 2019
Nathan T RossRohan E J Beckwith
bioRxiv

Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML

bioRxivNovember 26, 2019
James S SmitthKienan I Savage
8
Scientific Reports

Thymic precursor cells generate acute myeloid leukemia in NUP98-PHF23/NUP98-HOXD13 double transgenic mice

Scientific ReportsNovember 20, 2019
Subhadip KunduPeter D Aplan
1
Leukemia

Lineage of measurable residual disease in patients with chronic myeloid leukemia in treatment-free remission

LeukemiaNovember 25, 2019
Ilaria Stefania PaganiDavid Morrall Ross
3
Scientific Reports

The Prognostic Significance of PDE7B in Cytogenetically Normal Acute Myeloid Leukemia

Scientific ReportsNovember 18, 2019
Ling CaoXiaoliang Yuan
2
Cancers

Novel and Rare Fusion Transcripts Involving Transcription Factors and Tumor Suppressor Genes in Acute Myeloid Leukemia

CancersDecember 5, 2019
Antonella PadellaGiovanni Martinelli
bioRxiv

Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting

bioRxivNovember 22, 2019
Domenico ViolaFlavia Pichiorri
4
bioRxiv

The Topology of Mutated Driver Pathways

bioRxivNovember 30, 2019
Raouf DridiSridhar Tayur
4
Blood

Myeloid Cell-Targeted miR-146a Mimic Inhibits NF-kB-Driven Inflammation and Leukemia Progression in Vivo

BloodDecember 5, 2019
Yu-Lin SuMarcin Kortylewski
2
Cancer Cell

HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

Cancer CellNovember 27, 2019
Huacheng LuoSuming Huang
26
bioRxiv

Reprogrammed mRNA translation drives metabolic response to therapeutic targeting of ribosome biogenesis

bioRxivNovember 20, 2019
Eric P KusnadiRichard B Pearson
3
Leukemia

Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL

LeukemiaNovember 26, 2019
Sonia C RodriguezNadia Carlesso
8
Cancer Discovery

Resistance mechanisms to SYK inhibition in acute myeloid leukemia

Cancer DiscoveryNovember 26, 2019
Anjali CremerKimberly Stegmaier
12
Molecular Oncology

Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells

Molecular OncologyDecember 10, 2019
Nina OrfaliSharon L McKenna
Journal of Hepatology

The Phosphatidylethanolamine Biosynthesis Pathway Provides a New Target for Cancer Chemotherapy

Journal of HepatologyNovember 21, 2019
Yuan GuanGary Peltz
17
Leukemia

RNA-binding protein IGF2BP1 maintains leukemia stem cell properties by regulating HOXB4, MYB, and ALDH1A1

LeukemiaNovember 25, 2019
Irina A ElchevaVladimir S Spiegelman
Cancer Research

Single-cell gene expression analyses reveal distinct self-renewing and proliferating subsets in the leukemia stem cell compartment in acute myeloid leukemia

Cancer ResearchNovember 29, 2019
Karen SachsZohar Sachs
7
Genome Medicine

Immune receptor repertoires in pediatric and adult acute myeloid leukemia

Genome MedicineNovember 26, 2019
Jian Cheng ZhangX Shirley Liu
1

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