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Acute Myeloid Leukaemia & RNA

Acute myeloid leukaemia (AML) is a common hematological type of cancer. As the population ages, there has been a rise in the frequency of AML. RNA expression has been used to see if there are different genetic profiles that exist within AML and whether these may underpin the variations in survival rates. Here is the latest research on AML and RNA.

Top 20 most recent papers

Valproate and Retinoic Acid in Combination With Decitabine in Elderly Nonfit Patients With Acute Myeloid Leukemia: Results of a Multicenter, Randomized, 2 × 2, Phase II Trial

Journal of Clinical Oncology : Official Journal of the American Society of Clinical OncologyDecember 3, 2019

Michael LübbertDECIDER Study Team

The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

Nature CommunicationsNovember 25, 2019

Dimitrios PapaioannouRamiro Garzon

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma

Nature Chemical BiologyDecember 9, 2019

Nathan T RossRohan E J Beckwith

Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML

bioRxivNovember 26, 2019

James S SmitthKienan I Savage

Thymic precursor cells generate acute myeloid leukemia in NUP98-PHF23/NUP98-HOXD13 double transgenic mice

Scientific ReportsNovember 20, 2019

Subhadip KunduPeter D Aplan

Lineage of measurable residual disease in patients with chronic myeloid leukemia in treatment-free remission

LeukemiaNovember 25, 2019

Ilaria Stefania PaganiDavid Morrall Ross

The Prognostic Significance of PDE7B in Cytogenetically Normal Acute Myeloid Leukemia

Scientific ReportsNovember 18, 2019

Ling CaoXiaoliang Yuan

Novel and Rare Fusion Transcripts Involving Transcription Factors and Tumor Suppressor Genes in Acute Myeloid Leukemia

CancersDecember 5, 2019

Antonella PadellaGiovanni Martinelli

Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting

bioRxivNovember 22, 2019

Domenico ViolaFlavia Pichiorri

The Topology of Mutated Driver Pathways

bioRxivNovember 30, 2019

Raouf DridiSridhar Tayur

Myeloid Cell-Targeted miR-146a Mimic Inhibits NF-kB-Driven Inflammation and Leukemia Progression in Vivo

BloodDecember 5, 2019

Yu-Lin SuMarcin Kortylewski

HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

Cancer CellNovember 27, 2019

Huacheng LuoSuming Huang

Reprogrammed mRNA translation drives metabolic response to therapeutic targeting of ribosome biogenesis

bioRxivNovember 20, 2019

Eric P KusnadiRichard B Pearson

Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL

LeukemiaNovember 26, 2019

Sonia C RodriguezNadia Carlesso

Resistance mechanisms to SYK inhibition in acute myeloid leukemia

Cancer DiscoveryNovember 26, 2019

Anjali CremerKimberly Stegmaier

Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells

Molecular OncologyDecember 10, 2019

Nina OrfaliSharon L McKenna

The Phosphatidylethanolamine Biosynthesis Pathway Provides a New Target for Cancer Chemotherapy

Journal of HepatologyNovember 21, 2019

Yuan GuanGary Peltz

RNA-binding protein IGF2BP1 maintains leukemia stem cell properties by regulating HOXB4, MYB, and ALDH1A1

LeukemiaNovember 25, 2019

Irina A ElchevaVladimir S Spiegelman

Single-cell gene expression analyses reveal distinct self-renewing and proliferating subsets in the leukemia stem cell compartment in acute myeloid leukemia

Cancer ResearchNovember 29, 2019

Karen SachsZohar Sachs

Immune receptor repertoires in pediatric and adult acute myeloid leukemia

Genome MedicineNovember 26, 2019

Jian Cheng ZhangX Shirley Liu

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