Feed Preview

Acute Myeloid Leukaemia & RNA

Acute Myeloid Leukaemia & RNA diagram by undefined

Acute myeloid leukaemia (AML) is a common hematological type of cancer. As the population ages, there has been a rise in the frequency of AML. RNA expression has been used to see if there are different genetic profiles that exist within AML and whether these may underpin the variations in survival rates. Here is the latest research on AML and RNA.

Top 20 most recent papers
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

Valproate and Retinoic Acid in Combination With Decitabine in Elderly Nonfit Patients With Acute Myeloid Leukemia: Results of a Multicenter, Randomized, 2 × 2, Phase II Trial

Journal of Clinical Oncology : Official Journal of the American Society of Clinical OncologyDecember 3, 2019
Michael LübbertDECIDER Study Team
Nature Communications

The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

Nature CommunicationsNovember 25, 2019
Dimitrios PapaioannouRamiro Garzon
Nature Chemical Biology

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma

Nature Chemical BiologyDecember 9, 2019
Nathan T RossRohan E J Beckwith

Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML

bioRxivNovember 26, 2019
James S SmitthKienan I Savage
Scientific Reports

Thymic precursor cells generate acute myeloid leukemia in NUP98-PHF23/NUP98-HOXD13 double transgenic mice

Scientific ReportsNovember 20, 2019
Subhadip KunduPeter D Aplan

Lineage of measurable residual disease in patients with chronic myeloid leukemia in treatment-free remission

LeukemiaNovember 25, 2019
Ilaria Stefania PaganiDavid Morrall Ross
Scientific Reports

The Prognostic Significance of PDE7B in Cytogenetically Normal Acute Myeloid Leukemia

Scientific ReportsNovember 18, 2019
Ling CaoXiaoliang Yuan

Novel and Rare Fusion Transcripts Involving Transcription Factors and Tumor Suppressor Genes in Acute Myeloid Leukemia

CancersDecember 5, 2019
Antonella PadellaGiovanni Martinelli

Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting

bioRxivNovember 22, 2019
Domenico ViolaFlavia Pichiorri

The Topology of Mutated Driver Pathways

bioRxivNovember 30, 2019
Raouf DridiSridhar Tayur

Myeloid Cell-Targeted miR-146a Mimic Inhibits NF-kB-Driven Inflammation and Leukemia Progression in Vivo

BloodDecember 5, 2019
Yu-Lin SuMarcin Kortylewski
Cancer Cell

HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

Cancer CellNovember 27, 2019
Huacheng LuoSuming Huang

Reprogrammed mRNA translation drives metabolic response to therapeutic targeting of ribosome biogenesis

bioRxivNovember 20, 2019
Eric P KusnadiRichard B Pearson

Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL

LeukemiaNovember 26, 2019
Sonia C RodriguezNadia Carlesso
Cancer Discovery

Resistance mechanisms to SYK inhibition in acute myeloid leukemia

Cancer DiscoveryNovember 26, 2019
Anjali CremerKimberly Stegmaier
Molecular Oncology

Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells

Molecular OncologyDecember 10, 2019
Nina OrfaliSharon L McKenna
Journal of Hepatology

The Phosphatidylethanolamine Biosynthesis Pathway Provides a New Target for Cancer Chemotherapy

Journal of HepatologyNovember 21, 2019
Yuan GuanGary Peltz

RNA-binding protein IGF2BP1 maintains leukemia stem cell properties by regulating HOXB4, MYB, and ALDH1A1

LeukemiaNovember 25, 2019
Irina A ElchevaVladimir S Spiegelman
Cancer Research

Single-cell gene expression analyses reveal distinct self-renewing and proliferating subsets in the leukemia stem cell compartment in acute myeloid leukemia

Cancer ResearchNovember 29, 2019
Karen SachsZohar Sachs
Genome Medicine

Immune receptor repertoires in pediatric and adult acute myeloid leukemia

Genome MedicineNovember 26, 2019
Jian Cheng ZhangX Shirley Liu

See more papers from this feed

Related Feeds

AAV-based Gene Therapy

Adeno-associated virus (AAV)-based gene therapy is a biological vector that is being researched to be used as a potential therapeutic option. This gene therapy is designed to insert fragments of DNA into targeted cells to help treat diseases, such as hemophilia a. Discover the latest research on AAV-based gene therapy here.

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous disease with approximately 20,000 cases per year in the United States. AML also accounts for 15-20% of all childhood acute leukemias, while it is responsible for more than half of the leukemic deaths in these patients. Here is the latest research on this disease.

Alzheimer's Disease: Genetics

Alzheimer's disease is a chronic neurodegenerative disease. Discover genetic and epigenetic aspects of Alzheimer’s disease, including genetic markers and genomic structural variations here.

Antisense Oligonucleotides: ND

This feed focuses on antisense oligonucleotide therapies such as Inotersen, Nusinursen, and Patisiran, in neurodegenerative diseases including amyotrophic lateral sclerosis.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Autoimmune Lymphoproliferative Syndrome

Autoimmune lymphoproliferative syndrome (ALPS) is a rare genetic disorder of abnormal lymphocyte survival caused by defective Fas mediated apoptosis. Discover the latest research on ALPS here.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

© 2019 Meta ULC. All rights reserved