Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous disease with approximately 20,000 cases per year in the United States. AML also accounts for 15-20% of all childhood acute leukemias, while it is responsible for more than half of the leukemic deaths in these patients. Here is the latest research on this disease.

October 25, 2020
Preprint
Open Access

RNF5 Regulation of RBBP4 Defines Acute Myeloid Leukemia Growth and Susceptibility to Histone Deacetylase Inhibitors

BioRxiv : the Preprint Server for Biology
A. KhatebZe'ev A Ronai
October 24, 2020
Open Access

Antileukemic activity of the VPS34-IN1 inhibitor in acute myeloid leukemia

Oncogenesis
Godelieve MeunierDidier Bouscary
October 28, 2020
Open Access

Effect of rhG-CSF Combined With Decitabine Prophylaxis on Relapse of Patients With High-Risk MRD-Negative AML After HSCT: An Open-Label, Multicenter, Randomized Controlled Trial

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Lei GaoXi Zhang
October 27, 2020
Open Access

Emerging epigenetic therapeutics for myeloid leukemia: modulating demethylase activity with ascorbate

Haematologica
Andrew B DasMargreet C M Vissers
October 26, 2020
Preprint
Open Access

Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells

BioRxiv : the Preprint Server for Biology
J. A. ThomsJohn E Pimanda
October 28, 2020

Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia

The Journal of Clinical Investigation
Alhomidi AlmotiriNeil P Rodrigues
October 26, 2020

Acute myeloid leukemia with mutated NPM1 mimics acute promyelocytic leukemia presentation

International Journal of Laboratory Hematology
Manuel J Arana RosainzLei Chen
October 24, 2020
Open Access

Synthesis, Crystallography, and Anti-Leukemic Activity of the Amino Adducts of Dehydroleucodine

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Paola E OrdóñezCesar M Compadre
October 24, 2020

CLEC12A and CD33 co-expression as preferential target on pediatric AML for combinatorial immunotherapy

Blood
Semjon WillierTobias Feuchtinger
October 23, 2020
Open Access

Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics

Nature Communications
Kiyomi MoritaKoichi Takahashi
October 27, 2020

The Prognostic Significance of the BMI-1 and BAALC Genes in Adult Patients with Acute Myeloid Leukemia

Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion
Nevine F ShafikNaglaa M Hassan
October 27, 2020
Open Access

Ex vivo enrichment of PRAME antigen-specific T cells for adoptive immunotherapy using CD137 activation marker selection

Clinical & Translational Immunology
Koon H LeeEmily Blyth
October 27, 2020

Role of Radiotherapy and Chemotherapy in the Risk of Leukemia after Childhood Cancer: An International Pooled Analysis

International Journal of Cancer. Journal International Du Cancer
Rodrigue S AllodjiFlorent de Vathaire
October 29, 2020

TYRO3 Truncation Resulting From a t(10;15)(p11;q15) Chromosomal Translocation in Pediatric Acute Myeloid Leukemia

Anticancer Research
Marta BrunettiIoannis Panagopoulos
October 17, 2020
Review
Open Access

Application of Chimeric Antigen Receptor T Cells in the Treatment of Hematological Malignancies

BioMed Research International
Weiqi YanJian Yu

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