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Adult Kidney Organoids at Single Cell Resolution

Adult Kidney Organoids at Single Cell Resolution diagram by Marie Held et al.
Marie Held et al.

Single-cell RNA sequencing of the adult human kidney transcriptome can provide molecular information about cell-specific responses to environmental variables and disease states. This information can provide a dataset to benchmark human kidney organoids. Discover the latest research on adult kidney organoids at single cell resolution here.

Top 20 most recent papers

Organoid single-cell genomic atlas uncovers human-specific features of brain development

NatureOctober 1, 2019
Sabina KantonJ. Gray Camp
Nature Communications

Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation

Nature CommunicationsNovember 29, 2019
Ayshwarya SubramanianAnna Greka

High-Resolution 3D Fluorescent Imaging of Intact Tissues

bioRxivNovember 26, 2019
Danny El-NachefWilliam R MacLellan
Scientific Reports

FGF Signalling in the Self-Renewal of Colon Cancer Organoids

Scientific ReportsNovember 22, 2019
Jörg OtteJames A Adjaye

Human-specific regulatory features of brain development manifest staggering breadth of associations with physiological processes and pathological conditions of H. sapiens

bioRxivNovember 20, 2019
Gennadi V Glinsky

GO: A functional reporter system to identify and enrich base editing activity

bioRxivDecember 3, 2019
Alyna KattiLukas E. Dow
Nature Communications

Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma

Nature CommunicationsNovember 26, 2019
Shuang ZhangBenjamin G. Neel

Characterization of HIF-dependent alternative isoforms in pancreatic cancer

bioRxivOctober 31, 2019
Philipp MarkolinGunnar Raetsch
Scientific Reports

Ultra-thin fluorocarbon foils optimise multiscale imaging of three-dimensional native and optically cleared specimens

Scientific ReportsNovember 21, 2019
Katharina HötteFrancesco Pampaloni
Nature Communications

Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals

Nature CommunicationsOctober 11, 2019
Theodora YungTae-Hee Kim

Persistence of a novel regeneration-associated transitional cell state in pulmonary fibrosis

bioRxivNovember 25, 2019
Yoshihiko KobayashiPurushothama Rao Tata

NASH patient liver derived organoids exhibit patient specific NASH phenotypes and drug responses.

bioRxivOctober 3, 2019
Sarah L McCarronTobias D. Raabe
The Journal of Clinical Investigation

Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses

The Journal of Clinical InvestigationOctober 8, 2019
Seiji KishiJoseph Vincent Bonventre
Stem Cell Reports

Morphological and Molecular Defects in Human Three-Dimensional Retinal Organoid Model of X-Linked Juvenile Retinoschisis

Stem Cell ReportsNovember 1, 2019
Kang-Chieh HuangShih-Hwa Chiou

Human URAT1/SLC22A12 gene promoter is regulated by 27-hydroxycholesterol through estrogen response elements

bioRxivNovember 6, 2019
Masaya MatsubayashiEiichiro Mori

Single-cell analysis of human retina identifies evolutionarily conserved and species-specific mechanisms controlling development.

bioRxivOctober 2, 2019
Yufeng LuBrian S. Clark
Journal of Hepatology

The Phosphatidylethanolamine Biosynthesis Pathway Provides a New Target for Cancer Chemotherapy

Journal of HepatologyNovember 21, 2019
Yuan GuanGary Peltz
Nature Cell Biology

Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration

Nature Cell BiologyNovember 4, 2019
Luigi AloiaMeritxell Huch

Comprehensive analysis of structural variants in breast cancer genomes using single molecule sequencing

bioRxivNovember 19, 2019
Sergey S. AganezovMichael C. Schatz
Journal of Indian Association of Pediatric Surgeons

Tissue Engineering and Stem Cell Therapy in Pediatric Urology

Journal of Indian Association of Pediatric SurgeonsOctober 2, 2019
Shilpa Sharma, Devendra Kumar Gupta

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