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Aging Genetics

Aging Genetics diagram by Zahn et al, PLOS Genetics
Zahn et al, PLOS Genetics

This feed focuses on aging epidemiology and genetic, epigenetic, and proteomic aspects underlying aging, as well as aging- associated biomarkers. Here the latest research in this domain.

Top 20 most recent papers
Nature Medicine

Personal aging markers and ageotypes revealed by deep longitudinal profiling

Nature MedicineJanuary 15, 2020
Sara AhadiMichael Snyder
1297
30
4
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences

Cholinergic White Matter Lesions, AD-Signature Cortical Thickness, and Change in Cognition: The Northern Manhattan Study

The Journals of Gerontology. Series A, Biological Sciences and Medical SciencesJanuary 17, 2020
Michelle R CauncaTatjana Rundek
Aging Cell

The lipid elongation enzyme ELOVL2 is a molecular regulator of aging in the retina

Aging CellJanuary 17, 2020
Daniel ChenDorota Skowronska-Krawczyk
22
9
Aging

Metformin attenuates cartilage degeneration in an experimental osteoarthritis model by regulating AMPK/mTOR

AgingJanuary 17, 2020
Xiaofeng FengDaozhang Cai
European Journal of Heart Failure

Effects of spironolactone on serum markers of fibrosis in people at high risk of developing heart failure: rationale, design and baseline characteristics of a proof-of-concept, randomised, precision-medicine, prevention trial. The Heart OMics in AGing (HOMAGE) trial

European Journal of Heart FailureJanuary 18, 2020
Pierpaolo PellicoriJohn G F Cleland
1
International Journal of Molecular Sciences

Epigenetic Signaling and RNA Regulation in Cardiovascular Diseases

International Journal of Molecular SciencesJanuary 17, 2020
Alessia MongelliCarlo Gaetano
Aging Medicine

Associations between a laboratory frailty index and adverse health outcomes across age and sex

Aging MedicineJanuary 17, 2020
Joanna M BlodgettKenneth Rockwood
Polymers

Aging Mechanism and Rejuvenating Possibility of SBS Copolymers in Asphalt Binders

PolymersJanuary 18, 2020
Fusong WangShaopeng Wu
Human Molecular Genetics

Reduction of Tet2 exacerbates early stage Alzheimer's pathology and cognitive impairments in 2 × Tg-ad mice

Human Molecular GeneticsJanuary 17, 2020
Liping LiQinwen Wang
Annals of Clinical and Translational Neurology

Circulating ceramide ratios and risk of vascular brain aging and dementia

Annals of Clinical and Translational NeurologyJanuary 18, 2020
Emer R McGrathSudha Seshadri
bioRxiv

Complex sex-specific age-related changes in DNA methylation including variability, epimutations and entropy

bioRxivJanuary 15, 2020
Igor YusipovClaudio Franceschi
3
The American Journal of Clinical Nutrition

Epigenetic aging in newborns: role of maternal diet

The American Journal of Clinical NutritionJanuary 17, 2020
Melinda PhangMichael R Skilton
22
Aging

Romo1 is involved in the immune response of glioblastoma by regulating the function of macrophages

AgingJanuary 17, 2020
Guan SunLei Shi
Aging

Lifestyle vs. pharmacological interventions for healthy aging

AgingJanuary 16, 2020
Regula Furrer, Christoph Handschin
Current Bladder Dysfunction Reports

New Diagnostics for Male Lower Urinary Tract Symptoms

Current Bladder Dysfunction ReportsJanuary 16, 2020
Natalie R SwavelyAdam P Klausner
Aging

Plasma ubiquitin C-terminal hydrolase L1 levels reflect disease stage and motor severity in Parkinson's disease

AgingJanuary 15, 2020
Adeline Su Lyn NgEng-King Tan
2
1
Scientific Reports

Association of glomerular DNA damage and DNA methylation with one-year eGFR decline in IgA nephropathy

Scientific ReportsJanuary 16, 2020
Kaori HayashiHiroshi Itoh
Journal of Cancer

Combining Bioinformatics and Experiments to Identify and Verify Key Genes with Prognostic Values in Endometrial Carcinoma

Journal of CancerJanuary 17, 2020
Wenchao ZhangBei Lin
1
Endocrine

Inhibition of thioredoxin 2 by intracellular methylglyoxal accumulation leads to mitochondrial dysfunction and apoptosis in INS-1 cells

EndocrineJanuary 16, 2020
Chongxiao LiuYan Dong
Reproduction : the Official Journal of the Society for the Study of Fertility

Inflammaging is associated with shifted macrophage ontogeny and polarization in the aging mouse ovary

Reproduction : the Official Journal of the Society for the Study of FertilityJanuary 16, 2020
Zijing ZhangLynae Maria Brayboy
1

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