Alexander Disease

Alexander disease is a rare neurological disorder caused by mutations in the astrocyte-specific intermediate filament protein glial fibrillary acidic protein (GFAP). Here is the latest research.

December 6, 2019
Review

Neuroprotective effects of curcumin through autophagy modulation

IUBMB Life
Fatemeh ForouzanfarAmirhossein Sahebkar
March 8, 2020

Infantile Alexander Disease Presenting with Hydrocephalus and Epileptic Spasms

Indian Journal of Pediatrics
Vykuntaraju K GowdaChandrajit Prasad
December 17, 2019
Review
Open Access

Refining the concept of GFAP toxicity in Alexander disease

Journal of Neurodevelopmental Disorders
Albee Messing
May 1, 2020
Case Report

All in Your Mind? New-Onset Dysphagia in a Previously Healthy Adolescent Child

Journal of Pediatric Intensive Care
Jake SequeiraMark Marinello
August 29, 2019
Open Access

Inflammatory neuropathology of infantile Alexander disease: A case report

Brain & Development
Kengo KoraTomokatsu Yoshida
January 29, 2020
Review

Neurometabolic Diseases in Children: Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy Features

Current Medical Imaging Reviews
Direnç Özlem Aksoy, Alpay Alkan
December 13, 2019

An update on clinical, pathological, diagnostic, and therapeutic perspectives of childhood leukodystrophies

Expert Review of Neurotherapeutics
Mahmoud Reza AshrafiAli Reza Tavasoli
April 1, 2020
Case Report

Severe worsening of adult-onset Alexander disease after minor head trauma: Report of two patients and review of the literature

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Chiara BenzoniEttore Salsano
November 21, 2019
Review
Open Access

Autophagy in Myelinating Glia

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Jillian BelgradR Douglas Fields
May 1, 2019

Neuropsychological features of adult form of Alexander disease

Journal of the Neurological Sciences
Lara DraghiSylvie H M J Piacentini
May 18, 2020
Case Report

Parkinsonism phenotype in a family with adult onset Alexander disease and a novel mutation of GFAP

Clinical Neurology and Neurosurgery
D Vázquez-JustesC González-Mingot
January 11, 2019
Case Report

A Case of Juvenile Alexander Disease Presenting as Microcephaly

Indian Journal of Pediatrics
Vykuntaraju K GowdaMaya D Bhat
November 30, 2019
Case Report
Open Access

A Novel Mutation of GFAP Causing Adult-Onset Alexander Disease

Frontiers in Neurology
Andrea CiammolaVincenzo Silani
August 28, 2020

Clinical characteristics of Alexander disease

Neurodegenerative Disease Management
Tomokatsu Yoshida
September 15, 2019
Review
Open Access

Animal models of leukodystrophy: a new perspective for the development of therapies

The FEBS Journal
Holly A Rutherford, Noémie Hamilton
January 21, 2020
Open Access

A case of Alexander disease with repeated loss of consciousness and with rapid aggravation of dysbasia by falling

Rinshō shinkeigaku = Clinical neurology
Yumi MatsuyamaTomokatsu Yoshida
October 5, 2019
Review
Open Access

General Pathophysiology of Astroglia

Advances in Experimental Medicine and Biology
Alexei VerkhratskyVladimir Parpura
November 5, 2019
Open Access

Site-specific phosphorylation and caspase cleavage of GFAP are new markers of Alexander disease severity

ELife
Rachel A BattagliaNatasha T Snider
September 6, 2019
Open Access

Relative stabilities of wild-type and mutant glial fibrillary acidic protein in patients with Alexander disease

The Journal of Biological Chemistry
Michael R HeavenMichael Brenner

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