Alpha-Synuclein Aggregation (MDS)

Alpha-synucleins are small proteins that are believed to restrict the mobility of synpatic vesicles and inhibit neurotransmitter release. Aggregation of these proteins have been linked to several types of neurodegenerative diseases including dementia with Lewy bodies and Parkinson's disease. Here is the latest research on α-synuclein aggregation.

December 7, 2021

Novel nanostructured resin infiltrant containing calcium phosphate nanoparticles to prevent enamel white spot lesions.

Journal of the Mechanical Behavior of Biomedical Materials
Zixiang DaiYuxing Bai
December 5, 2021
Preprint
Open Access

Structure-based discovery of small molecule inhibitors of the autocatalytic proliferation of alpha-synuclein aggregates

BioRxiv : the Preprint Server for Biology
S. ChiaMichele Vendruscolo
December 4, 2021

Brain atrophy progression in Parkinson's disease is shaped by connectivity and local vulnerability.

Brain Communications
Christina TremblayAlain Dagher
December 3, 2021
Comment / Editorial

Elevated norepinephrine may interact with alpha-synuclein to promote Parkinson's disease and DLB.

Acta Neurologica Scandinavica
Paul J Fitzgerald
December 1, 2021
Preprint
Open Access

Label-free characterisation of amyloids and alpha-Synuclein polymorphs by exploiting their intrinsic fluorescence property

BioRxiv : the Preprint Server for Biology
C. W. ChungGabriele S Kaminski Schierle
December 1, 2021

Targeted proteolytic products of τ and α-synuclein in neurodegeneration.

Essays in Biochemistry
Yuxing XiaBenoit I Giasson
November 30, 2021

[Hallucinations in Patients with Idiopathic Parkinson's Disease].

Fortschritte der Neurologie-Psychiatrie
Daniel WeissHeinz Reichmann
November 29, 2021
Review

Updates on the Genetics of Parkinson's Disease: Clinical Implications and Future Treatment.

Acta Neurologica Taiwanica
Yung-Tsai ChuRuey-Meei Wu
November 29, 2021

Independent effect of neurogenic orthostatic hypotension on mild cognitive impairment in Parkinson's disease.

Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society
Sung Hoon KangSeong-Beom Koh
November 29, 2021
Review

Antioxidative role of Traditional Chinese Medicine in Parkinson's disease.

Journal of Ethnopharmacology
Fahim MuhammadHongyu Li
November 28, 2021

Footprints of a microbial toxin from the gut microbiome to mesencephalic mitochondria.

Gut
A Raquel EstevesSandra Morais Cardoso
November 28, 2021
Correction
Open Access

Correction to: High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.

Acta Neuropathologica Communications
Marco J RussoUn Jung Kang
November 28, 2021

HYPK coordinates degradation of polyneddylated proteins by autophagy.

Autophagy
Debasish Kumar Ghosh, Akash Ranjan
November 28, 2021
Review

Alpha-Synuclein and Cognitive Decline in Parkinson Disease.

Life
Tian-Sin FanRuey-Meei Wu
November 28, 2021
Review
Open Access

Autophagy in α-Synucleinopathies-An Overstrained System.

Cells
Lisa FellnerFrank Edenhofer
November 28, 2021
Open Access

(De)stabilization of Alpha-Synuclein Fibrillary Aggregation by Charged and Uncharged Surfactants.

International Journal of Molecular Sciences
Joana Angélica LoureiroMaria Carmo Pereira

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