Alpha-Synuclein Aggregation

Alpha-synucleins are small proteins that are believed to restrict the mobility of synpatic vesicles and inhibit neurotransmitter release. Aggregation of these proteins have been linked to several types of neurodegenerative diseases including dementia with Lewy bodies and Parkinson's disease. Here is the latest research on α-synuclein aggregation.

January 17, 2021
Open Access

Phospholipids Uniquely Modify Secondary Structure of α-Synuclein Oligomers

BioRxiv : the Preprint Server for Biology
T. DouDmitry Kurouski
January 8, 2021
Open Access

Alpha-Synuclein Antibody Characterization: Why Semantics Matters

Molecular Neurobiology
Tiago Fleming Outeiro
January 17, 2021

Interplay between tau and α-synuclein LLPS

Protein Science : a Publication of the Protein Society
Anna SiegertMarkus Zweckstetter
January 3, 2021
Open Access

Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies

Journal of Molecular Cell Biology
Maarten C HardenbergMichele Vendruscolo
December 23, 2020

Acceleration of α-synuclein fibril formation and associated cytotoxicity stimulated by silica nanoparticles as a model of neurodegenerative diseases

International Journal of Biological Macromolecules
Chao PangMojtaba Falahati
January 3, 2021
Open Access

Distinct cryo-EM Structure of α-synuclein Filaments derived by Tau

BioRxiv : the Preprint Server for Biology
A. HojjatianKwang Hun Lim
December 30, 2020
Open Access

Exosomes in Parkinson Disease

Journal of Neurochemistry
Jennifer R PinnellKim Tieu
December 22, 2020

Role of RhoA-ROCK signaling in Parkinson's disease

European Journal of Pharmacology
Mahalaxmi IyerBalachandar Vellingiri
December 29, 2020
Open Access

11 C]MODAG-001-towards a PET tracer targeting α-synuclein aggregates

European Journal of Nuclear Medicine and Molecular Imaging
Laura KueblerKristina Herfert
December 19, 2020

Gut-Brain axis in Parkinson's disease etiology: The role of lipopolysaccharide

Chemistry and Physics of Lipids
Dipita Bhattacharyya, Anirban Bhunia
December 24, 2020
Open Access

Overexpression of human alpha-synuclein leads to dysregulated microbiome and metabolites with ageing in a rat model of Parkinson disease

BioRxiv : the Preprint Server for Biology
Yogesh SinghN. Casadei
January 12, 2021
Open Access

Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo

Neurobiology of Disease
Antonio Dominguez-MeijideTiago Fleming Outeiro
January 17, 2021
Open Access

Expression Levels of an Alpha-Synuclein Transcript in Blood May Distinguish between Early Dementia with Lewy Bodies and Parkinson's Disease

International Journal of Molecular Sciences
Laura Marsal-GarcíaKatrin Beyer
January 9, 2021

Distinguishing normal and aggregated alpha-synuclein interaction on gold nanorod incorporated zinc oxide nanocomposite by electrochemical technique

International Journal of Biological Macromolecules
Hussaini AdamUda Hashim
December 22, 2020

Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson's disease

Nutritional Neuroscience
Elvis CuevasSumit Sarkar
December 18, 2020
Open Access

Extracellular Vesicles Loaded miRNAs as Potential Modulators Shared Between Glioblastoma, and Parkinson's and Alzheimer's Diseases

Frontiers in Cellular Neuroscience
Laura ThomasCarolina Perez-Castro

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