ALS: Phenotypes

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder characterized phenotypically by progressive muscle weakness. Clinical phenotypes of ALS can be classified based on the pattern, level, and area of onset (e.g. bulbar, cervical, lumbar). Here is the latest research investigating phenotypes of ALS.

December 7, 2021
Preprint
Open Access

Ropinirole hydrochloride for amyotrophic lateral sclerosis: A single-center, randomized feasibility, double-blind, placebo-controlled trial

MedRxiv : the Preprint Server for Health Sciences
Satoru MorimotoHideyuki Okano
December 7, 2021
Review

Microglial TREM2 in amyotrophic lateral sclerosis.

Developmental Neurobiology
Manling XieLong-Jun Wu
December 6, 2021

Amyotrophic lateral sclerosis associated with a pathological expansion in the ATXN7 gene.

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration
Florent CluseAntoine Pegat
December 6, 2021
Open Access

Methylation and Expression of Mutant FUS in Motor Neurons Differentiated From Induced Pluripotent Stem Cells From ALS Patients.

Frontiers in Cell and Developmental Biology
T HartungS Petri
December 6, 2021
Open Access

Rare CYLD Variants in Chinese Patients With Amyotrophic Lateral Sclerosis.

Frontiers in Genetics
Xiaojing GuHuifang Shang
December 6, 2021

Neurofilament markers in serum and cerebrospinal fluid of patients with amyotrophic lateral sclerosis.

Journal of Cellular and Molecular Medicine
Jiaying ShiWei Zhang
December 3, 2021
Open Access

ALS patients with concurrent neuroinflammatory disorders; a nationwide clinical records study.

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration
Elisa LonginettiFang Fang
December 3, 2021

Validation of the DYALS (dysphagia in amyotrophic lateral sclerosis) questionnaire for the evaluation of dysphagia in ALS patients.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Luca DiamantiDYALS Study Group
November 28, 2021
Review

Nutrient Effects on Motor Neurons and the Risk of Amyotrophic Lateral Sclerosis.

Nutrients
Polina S GoncharovaNatalia A Shnayder
November 28, 2021
Review
Open Access

Nearly 30 Years of Animal Models to Study Amyotrophic Lateral Sclerosis: A Historical Overview and Future Perspectives.

International Journal of Molecular Sciences
Tiziana BonifacinoMarco Milanese
November 28, 2021
Open Access

Epigenetic Small Molecules Rescue Nucleocytoplasmic Transport and DNA Damage Phenotypes in C9ORF72 ALS/FTD.

Brain Sciences
Melina RamicZane Zeier
November 27, 2021

Reversible sub-acute motor neuron syndrome after mushroom intoxication masquerading as amyotrophic lateral sclerosis.

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration
Emmeline LagrangeWilliam Camu
November 27, 2021

A Brazilian multicentre study on the clinical and epidemiological profiles of 1116 patients with amyotrophic lateral sclerosis and its phenotypic variants.

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration
Christian Marques CoutoOsvaldo J M Nascimento
November 25, 2021

Laryngospasm in Amyotrophic Lateral Sclerosis.

Muscle & Nerve
Ryan D GotesmanAri Breiner
November 24, 2021
Preprint
Open Access

Astrocytic expression of ALS-causative mutant FUS leads to TNFa-dependent neurodegeneration in vivo

BioRxiv : the Preprint Server for Biology
B. K. JensenPiera Pasinelli

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