ALS - Phenotypes

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating phenotypes associated with this genetically heterogeneous disorder.

September 29, 2020
Review
Open Access

The Development of C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Disorders

Frontiers in Genetics
Qijie YangLu Shen
October 9, 2020
Open Access

Overexpression of UBQLN1 reduces neuropathology in the P497S UBQLN2 mouse model of ALS/FTD

Acta Neuropathologica Communications
Shaoteng WangMervyn J Monteiro
October 2, 2020
Open Access

L-Citrulline Level and Transporter Activity Are Altered in Experimental Models of Amyotrophic Lateral Sclerosis

Molecular Neurobiology
Asmita GyawaliYoung-Sook Kang
October 20, 2020
Review
Open Access

Amyotrophic Lateral Sclerosis: A Neurodegenerative Motor Neuron Disease With Ocular Involvement

Frontiers in Neuroscience
Pilar RojasJosé M Ramírez
October 6, 2020
Open Access

Type I PRMT Inhibition Protects Against C9ORF72 Arginine-Rich Dipeptide Repeat Toxicity

Frontiers in Pharmacology
Alan S PremasiriFernando G Vieira
October 23, 2020
Comment / Editorial

Sleep in ALS: more than discomfort or respiratory breathing disorder

Journal of Neurology, Neurosurgery, and Psychiatry
Adriano Chiò, Alessandro Cicolin
October 25, 2020
Open Access

Neurotrophic Properties of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Motor Neuron Disease

Toxins
Mireia Herrando-GrabulosaJosé Aguilera
October 22, 2020

C9orf72-associated frontotemporal dementia in the Russian population

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Yu A ShpilyukovaS N Illarioshkin
October 13, 2020
Open Access

Relationship between Dysarthria and Oral-Oropharyngeal Dysphagia: The present evidence

Ear, Nose, & Throat Journal
Brandon J WangKenneth W Altman
October 20, 2020
Review
Open Access

Natural Compounds and Autophagy: Allies Against Neurodegeneration

Frontiers in Cell and Developmental Biology
Alessandra Stacchiotti, Giovanni Corsetti
October 20, 2020
Open Access

Comparative Transcriptional Profiling of Motor Neuron Disorder-Associated Genes in Various Human Cell Culture Models

Frontiers in Cell and Developmental Biology
Stefan HauserLudger Schöls
October 9, 2020
Preprint
Open Access

In Vivo Validation of Bimolecular Fluorescence Complementation (BiFC) to Investigate Aggregate Formation in Amyotrophic Lateral Sclerosis (ALS)

BioRxiv : the Preprint Server for Biology
E. K. DonMarco Morsch
September 29, 2020
Open Access

Photovoice as A Participatory Research Tool in Amyotrophic Lateral Sclerosis

Journal of Neuromuscular Diseases
Adrianna GuntonKerri Lynn Schellenberg
September 30, 2020
Open Access

TDP-43 dysfunction results in R-loop accumulation and DNA replication defects

Journal of Cell Science
Matthew WoodAlessandro Vindigni
October 21, 2020
Preprint
Open Access

Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition

BioRxiv : the Preprint Server for Biology
K. Stoklund DittlauLudo Van Den Bosch
October 17, 2020
Review
Open Access

Activities of Daily Living and Associated Costs in the Most Widespread Neurodegenerative Diseases: A Systematic Review

Clinical Interventions in Aging
Petra MaresovaOndrej Krejcar
October 7, 2020
Open Access

Monoclonal full-length antibody against TAR DNA-binding protein 43 reduces related proteinopathy in neurons

JCI Insight
Silvia PozziJean-Pierre Julien
October 8, 2020

Full-length TDP-43 and its C-terminal domain form filaments in vitro having non-amyloid properties

Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis
Claudia CapitiniFabrizio Chiti

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