ALS: Prions

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion-like mechanisms are associated with the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). Here is the latest research on ALS and prions.

June 20, 2020

Evidence Linking Protein Misfolding to Quality Control in Progressive Neurodegenerative Diseases

Current Topics in Medicinal Chemistry
Md Tanvir KabirMohamed M Abdel-Daim
July 24, 2020
Review
Open Access

POSCAbilities: The Application of the Prion Organotypic Slice Culture Assay to Neurodegenerative Disease Research

Biomolecules
Hailey Pineau, Valerie Sim
January 16, 2021
Review

FUS and TDP-43 Phases in Health and Disease

Trends in Biochemical Sciences
Bede PortzJames Shorter
September 16, 2020
Review
Open Access

From Seeds to Fibrils and Back: Fragmentation as an Overlooked Step in the Propagation of Prions and Prion-Like Proteins

Biomolecules
Cristóbal Marrero-WinkensHermann M Schatzl
February 11, 2020
Correction
Open Access

Corrigendum: Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis

Frontiers in Molecular Neuroscience
Luke McAlaryNeil R Cashman
September 30, 2020
Review
Open Access

Fused in Sarcoma (FUS) in DNA Repair: Tango with Poly(ADP-ribose) Polymerase 1 and Compartmentalisation of Damaged DNA

International Journal of Molecular Sciences
Maria V SukhanovaOlga I Lavrik
August 29, 2020
Review
Open Access

Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases

International Journal of Molecular Sciences
Rose Ghemrawi, Mostafa Khair
August 23, 2020
Review
Open Access

C. elegans Models to Study the Propagation of Prions and Prion-Like Proteins

Biomolecules
Carl Alexander SandhofCarmen Nussbaum-Krammer
December 7, 2020
Preprint
Open Access

Sequence determinants for the aggregation and cytotoxicity of proteins within condensates generated by liquid-liquid phase separation

BioRxiv : the Preprint Server for Biology
M. Vendruscolo, MONIKA FUXREITER
September 16, 2020
Review

Phenotypic diversity in ALS and the role of poly-conformational protein misfolding

Acta Neuropathologica
Jacob I Ayers, David R Borchelt
December 15, 2020
Review

Extracellular vesicles - propagators of neuropathology and sources of potential biomarkers and therapeutics for neurodegenerative diseases

Journal of Cell Science
Natasha VassileffAndrew F Hill
June 21, 2020

Application of yeast to studying amyloid and prion diseases

Advances in Genetics
Yury O ChernoffTatiana A Chernova
September 15, 2020
Review
Open Access

The complex relationship between genotype, pathology and phenotype in familial dementia

Neurobiology of Disease
John B KwokGlenda M Halliday
September 16, 2020
Open Access

Aggregate-selective antibody attenuates seeded aggregation but not spontaneously evolving disease in SOD1 ALS model mice

Acta Neuropathologica Communications
Manuela LehmannUlrika Nordström
November 13, 2020
Review

Emerging potential of cannabidiol in reversing proteinopathies

Ageing Research Reviews
Raju DashIl Soo Moon
December 15, 2020
Open Access

Evidence that corticofugal propagation of ALS pathology is not mediated by prion-like mechanism

Progress in Neurobiology
Jelena Scekic-ZahirovicCaroline Rouaux
December 18, 2020
Open Access

Amyotrophic Lateral Sclerosis: Proteins, Proteostasis, Prions, and Promises

Frontiers in Cellular Neuroscience
L McAlaryNeil R Cashman
January 26, 2020

Sephin1 Reduces Prion Infection in Prion-Infected Cells and Animal Model

Molecular Neurobiology
Simrika ThapaHermann M Schatzl
January 22, 2021

Advances in genetics research in the pathogenesis of amyotrophic lateral sclerosis.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
Yan WangFangfang Bi

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