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ALS: Therapies

ALS: Therapies diagram by Vaccinationist, Wikimedia
Vaccinationist, Wikimedia

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS therapies here.

Top 20 most recent papers
Journal of Neurology, Neurosurgery, and Psychiatry

Prognosis of amyotrophic lateral sclerosis patients undergoing tracheostomy invasive ventilation therapy in Japan

Journal of Neurology, Neurosurgery, and PsychiatryJanuary 16, 2020
Naoki HayashiGen Sobue
5
bioRxiv

An overview of the quality assurance and quality control of magnetic resonance imaging data for the Ontario Neurodegenerative Disease Research Initiative (ONDRI): pipeline development and neuroinformatics

bioRxivJanuary 16, 2020
Christopher J. M. ScottThe ONDRI investigators
1
The EMBO Journal

Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders

The EMBO JournalJanuary 14, 2020
Manon BoivinNicolas Charlet-Berguerand
5
1
Scientific Reports

Microendoscopy detects altered muscular contractile dynamics in a mouse model of amyotrophic lateral sclerosis

Scientific ReportsJanuary 18, 2020
Xuefeng ChenScott L Delp
Journal of Neurology, Neurosurgery, and Psychiatry

Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes

Journal of Neurology, Neurosurgery, and PsychiatryJanuary 16, 2020
Lucas VuRobert Bowser
3
1
bioRxiv

Estimating the rate of cell type degeneration from epigenetic sequencing of cell-free DNA

bioRxivJanuary 16, 2020
Christa CaggianoNoah Zaitlen
28
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Analyzing progression of motor and speech impairment in ALS

Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology SocietyJanuary 18, 2020
Carla AgurtoNicholas J Maragakis
Cells

Mitophagy in Alzheimer's Disease and Other Age-Related Neurodegenerative Diseases

CellsJanuary 16, 2020
Qian Cai, Yu Young Jeong
2
1
Journal of Neuropathology and Experimental Neurology

Neuropathology of Speech Network Distinguishes Bulbar From Nonbulbar Amyotrophic Lateral Sclerosis

Journal of Neuropathology and Experimental NeurologyJanuary 18, 2020
Sanjana ShellikeriYana Yunusova
Journal of Neuropathology and Experimental Neurology

Linear Polyubiquitin Chain Modification of TDP-43-Positive Neuronal Cytoplasmic Inclusions in Amyotrophic Lateral Sclerosis

Journal of Neuropathology and Experimental NeurologyJanuary 18, 2020
Yoshiaki NakayamaHidefumi Ito
1
Revue neurologique

Pre-symptomatic diagnosis in ALS

Revue neurologiqueJanuary 15, 2020
P Corciaon Behalf the FILSLAN network
1
The European Journal of Neuroscience

The influence of metallothionein treatment and treadmill running exercise on disease onset and survival in SOD1G93A amyotrophic lateral sclerosis mice

The European Journal of NeuroscienceJanuary 19, 2020
Katherine Ea LewisMeng Inn Chuah
bioRxiv

Variant-specific changes in persistent or resurgent Na+ current in SCN8A-EIEE13 iPSC-derived neurons

bioRxivJanuary 18, 2020
Andrew M TidballJack M Parent
Journal of Neurology

ALS-derived fibroblasts exhibit reduced proliferation rate, cytoplasmic TDP-43 aggregation and a higher susceptibility to DNA damage

Journal of NeurologyJanuary 16, 2020
Javier RianchoMiguel Lafarga
1
Journal of Neurology, Neurosurgery, and Psychiatry

Chitinases, neuroinflammation and biomarkers in ALS

Journal of Neurology, Neurosurgery, and PsychiatryJanuary 16, 2020
Michael Swash
1
Journal of Neuroinflammation

The progress of gut microbiome research related to brain disorders

Journal of NeuroinflammationJanuary 19, 2020
Sibo ZhuXingdong Chen
European Journal of Radiology

Toward a marker of upper motor neuron impairment in amyotrophic lateral sclerosis: A fully automatic investigation of the magnetic susceptibility in the precentral cortex

European Journal of RadiologyJanuary 17, 2020
Valeria Elisa ContarinoFabio Triulzi
2
Trends in Genetics : TIG

Omics in Neurodegenerative Disease: Hope or Hype?

Trends in Genetics : TIGJanuary 15, 2020
Maria E Diaz-Ortiz, Alice S Chen-Plotkin
28
1
JAMA Neurology

Safety and Efficacy of RimabotulinumtoxinB for Treatment of Sialorrhea in Adults: A Randomized Clinical Trial

JAMA NeurologyJanuary 14, 2020
Stuart H IsaacsonMYSTICOL Study Group
8
1
International Journal of Molecular Sciences

Repurposing Potential of Riluzole as an ITAF Inhibitor in mTOR Therapy Resistant Glioblastoma

International Journal of Molecular SciencesJanuary 18, 2020
Angelica Benavides-SerratoJoseph Gera
1

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