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ALS: Therapies

ALS: Therapies diagram by Vaccinationist
Vaccinationist

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS therapies here.

Top 20 most recent papers
Neurology

Prediagnostic plasma polyunsaturated fatty acids and the risk of amyotrophic lateral sclerosis

NeurologyDecember 3, 2019
Eilis Joan O'ReillyAlberto A Ascherio
1
bioRxiv

Comprehensive identification of HSP70/HSC70 Chaperone Clients in Human Cells

bioRxivDecember 4, 2019
Seung W RyuTanya T. Paull
8
bioRxiv

Serial assessment of iron in the motor cortex in limb-onset Amyotrophic Lateral Sclerosis using Quantitative Susceptibility Mapping

bioRxivDecember 6, 2019
Anjan BhattaraiPhyllis Chua
7
ACS Chemical Neuroscience

A native mass spectrometry-based method for studying stilbenoid effects on the stabilities and aggregation of Cu, Zn-superoxide dismutase

ACS Chemical NeuroscienceDecember 10, 2019
Xiaoyu ZhuangJian-Zhong Lu
BMJ Open

Induced pluripotent stem cell-based Drug Repurposing for Amyotrophic lateral sclerosis Medicine (iDReAM) study: protocol for a phase I dose escalation study of bosutinib for amyotrophic lateral sclerosis patients

BMJ OpenDecember 2, 2019
Keiko ImamuraHaruhisa Inoue
1
Gene Therapy

The deletion of mutant SOD1 via CRISPR/Cas9/sgRNA prolongs survival in an amyotrophic lateral sclerosis mouse model

Gene TherapyDecember 9, 2019
Weisong DuanChun-Yan Li
Molecular Brain

RT2 PCR array screening reveals distinct perturbations in DNA damage response signaling in FUS-associated motor neuron disease

Molecular BrainDecember 4, 2019
Hai-Bo WangMuralidhar L Hegde
5
Genes

Existing and Emerging Metabolomic Tools for ALS Research

GenesDecember 5, 2019
Christine GermeysLudo Van Den Bosch
Biomolecules

Evolutionary Analyses of Sequence and Structure Space Unravel the Structural Facets of SOD1

BiomoleculesDecember 4, 2019
Sourav ChowdhuryKrishnananda Chattopadhyay
Stem Cells Translational Medicine

Spinal parenchymal occupation by neural stem cells after subpial delivery in adult immunodeficient rats

Stem Cells Translational MedicineDecember 4, 2019
Martin MarsalaJoseph D Ciacci
11
2
Cells

JNK Signaling Pathway Involvement in Spinal Cord Neuron Development and Death

CellsDecember 5, 2019
Roberta SchellinoAlessandro Vercelli
Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition

Interventions to promote oral nutritional behaviours in people living with neurodegenerative disorders of the motor system: A systematic review

Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral NutritionNovember 19, 2019
Munira EssatHighCALS group
Cells

The Impact of Kinases in Amyotrophic Lateral Sclerosis at the Neuromuscular Synapse: Insights into BDNF/TrkB and PKC Signaling

CellsDecember 5, 2019
Maria Angel LanuzaJosep Maria Tomàs
Nature Communications

Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization

Nature CommunicationsDecember 6, 2019
Ian CasciUdai Bhan Pandey
25
Cellular and Molecular Life Sciences : CMLS

Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress

Cellular and Molecular Life Sciences : CMLSDecember 4, 2019
Mark A HalloranJulie D Atkin
5
Water Research

Production of the neurotoxin beta-N-methylamino-l-alanine may be triggered by agricultural nutrients: An emerging public health issue

Water ResearchNovember 26, 2019
Yanyan Zhang, Joann K Whalen
5
1
Analytical Chemistry

A Sample-Sample Correlation Asynchronous Spectroscopic Method Coupled with MCR-ALS to Analyze Challenging Bilinear Data

Analytical ChemistryDecember 6, 2019
Ran GuoJin-guang Wu
Current Pharmaceutical Design

Neurofilament proteins as prognostic biomarkers in neurological disorders

Current Pharmaceutical DesignDecember 10, 2019
Yi-Chen LeeBak-Sau Yip
EBioMedicine

Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity

EBioMedicineNovember 28, 2019
Anastasya BirgerBenjamin E Reubinoff
3
1
BioMed Research International

Review on Cross Talk between Neurotransmitters and Neuroinflammation in Striatum and Cerebellum in the Mediation of Motor Behaviour

BioMed Research InternationalNovember 14, 2019
Dayang Yasmin Abg Abd WahabSangu Muthuraju

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