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Alzheimer's Disease: Animal models

Alzheimer's Disease: Animal models diagram by Castello et al, PLOS One
Castello et al, PLOS One

Alzheimer's disease is a chronic neurodegenerative disease which can be studied using various experimental systems. This feed focuses on animal models used for Alzheimer's disease research.

Top 20 most recent papers
Nature Medicine

Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease

Nature MedicineJanuary 15, 2020
Yingyue ZhouMarco Colonna
44
1
Cell Reports

GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models

Cell ReportsJanuary 16, 2020
Jesse E HansonJorge J Palop
7
20
1
Journal of Alzheimer's Disease : JAD

Effect Modifiers of TDP-43 Associated Hippocampal Atrophy Rates in Patients with Alzheimer's Disease Neuropathological Changes

Journal of Alzheimer's Disease : JADJanuary 14, 2020
Marina BuciucKeith A Josephs
Nature

Publisher Correction: Dietary salt promotes cognitive impairment through tau phosphorylation

NatureJanuary 15, 2020
Giuseppe FaracoCostantino Iadecola
4
3
bioRxiv

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

bioRxivJanuary 15, 2020
Man Ying WongWenjie Luo
3
Alzheimer's Research & Therapy

Effector function of anti-pyroglutamate-3 Aβ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer's-like mice

Alzheimer's Research & TherapyJanuary 15, 2020
Helen CrehanCynthia A Lemere
Neurobiology of Aging

Cognitive reserve and rate of change in Alzheimer's and cerebrovascular disease biomarkers among cognitively normal individuals

Neurobiology of AgingJanuary 15, 2020
Corinne PettigrewMarilyn Albert
Neurobiology of Disease

Insulin deficiency promotes formation of toxic amyloid-β42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model

Neurobiology of DiseaseJanuary 14, 2020
Tomohiro ImamuraJun-Ichi Kira
Molecular and Cellular Biology

Nrf2 Suppresses Oxidative Stress and Inflammation in App Knock-in Alzheimer's Disease Model Mice

Molecular and Cellular BiologyJanuary 15, 2020
Akira UrunoMasayuki Yamamoto
2
bioRxiv

A Temporal Quantitative Profiling of Newly Synthesized Proteins during Aβ Accumulation

bioRxivJanuary 15, 2020
Yuanhui maJohn Robert Yates
1
bioRxiv

Apolipoprotein E4 disrupts the neuroprotective action of sortilin in neuronal lipid metabolism and endocannabinoid signaling

bioRxivJanuary 14, 2020
Antonino AsaroThomas Willnow
13
Nature Communications

Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect

Nature CommunicationsJanuary 12, 2020
Guilin PiJian-Zhi Wang
Redox Biology

7-O-Esters of taxifolin with pronounced and overadditive effects in neuroprotection, anti-neuroinflammation, and amelioration of short-term memory impairment in vivo

Redox BiologyJanuary 14, 2020
Sandra GuneschMichael Decker
Neurobiology of Aging

Distance disintegration delineates the brain connectivity failure of Alzheimer's disease

Neurobiology of AgingJanuary 17, 2020
Víctor CostumeroJorge Sepulcre
Journal of Alzheimer's Disease : JAD

Chromogranin A Analysis in the Differential Diagnosis Across Lewy Body Disorders

Journal of Alzheimer's Disease : JADJanuary 14, 2020
Karin GmitterovaInga Zerr
Neurobiology of Disease

Every-other-day feeding exacerbates inflammation and neuronal deficits in 5XFAD mouse model of Alzheimer's disease

Neurobiology of DiseaseJanuary 14, 2020
Divna LazicMilka Perovic
8
Journal of Alzheimer's Disease : JAD

Asthma and Chronic Obstructive Pulmonary Disease as a Comorbidity and Association with the Choice of Antidementia Medication Among Persons with Alzheimer's Disease

Journal of Alzheimer's Disease : JADJanuary 14, 2020
Pasi LampelaHeidi Taipale
Journal of Alzheimer's Disease : JAD

Cortical Superficial Siderosis: A Descriptive Analysis in a Memory Clinic Population

Journal of Alzheimer's Disease : JADJanuary 14, 2020
Aline MendesGabriel Gold
1
Journal of Alzheimer's Disease : JAD

Cerebrospinal Fluid Levels of Interleukin-8 in Delirium, Dementia, and Cognitively Healthy Patients

Journal of Alzheimer's Disease : JADJanuary 14, 2020
Muhammad Umar SajjadLeiv Otto Watne
Journal of Alzheimer's Disease : JAD

Association of Hypercholesterolemia with Alzheimer's Disease Pathology and Cerebral Amyloid Angiopathy

Journal of Alzheimer's Disease : JADJanuary 14, 2020
Chenjia XuSujuan Gao

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