Alzheimer's Disease: APOE

Apolipoprotein E (APOE) polymorphic alleles are major genetic risk factors for Alzheimer's disease. Discover the latest research on APOE and other genetic determinants of Alzheimer's disease here.

February 25, 2021

Cerebral amyloid angiopathy-related inflammation: current status and future implications.

Chinese Medical Journal
Juan-Juan WuJun Ni
February 22, 2021
Open Access

KL∗VS heterozygosity reduces brain amyloid in asymptomatic at-risk APOE∗4 carriers.

Neurobiology of Aging
Michael E BelloyAlzheimer's Disease Neuroimaging Initiative
February 23, 2021
Open Access

APOE and MAPT Are Associated With Dementia in Neuropathologically Confirmed Parkinson's Disease.

Frontiers in Neurology
Jon-Anders TunoldLasse Pihlstrøm
February 23, 2021
Open Access

Brain health registry GenePool study: A novel approach to online genetics research.

Alzheimer's & Dementia : Translational Research & Clinical Interventions
Juliet FocklerRachel L Nosheny
February 23, 2021
Open Access

The human hippocampus and its subfield volumes across age, sex and APOE e4 status.

Brain Communications
Michele VeldsmanMasud Husain
February 23, 2021

Vascular Lesions, APOE ε4, and Tau Pathology in Alzheimer Disease.

Journal of Neuropathology and Experimental Neurology
Jodie B NicholsThomas G Beach
February 21, 2021
Review
Open Access

Olfactory impairment in men and mice related to aging and amyloid-induced pathology.

Pflügers Archiv : European journal of physiology
Wen-Yu TzengOlga Garaschuk
February 21, 2021
Review
Open Access

Microglial phagocytosis of neurons in neurodegeneration, and its regulation.

Journal of Neurochemistry
Claire A ButlerGuy C Brown
February 20, 2021
Open Access

Disease progression modelling from preclinical Alzheimer's disease (AD) to AD dementia.

Scientific Reports
Soo Hyun ChoSang Won Seo
February 20, 2021

White matter aging drives microglial diversity.

Neuron
Shima SafaiyanMikael Simons
February 19, 2021

APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function.

Science Translational Medicine
Monica XiongDavid M Holtzman
February 18, 2021
Open Access

Cognitive, physical and disability trajectories in community-dwelling elderly people.

Aging Clinical and Experimental Research
Ottavia Eleonora FerraroSimona Villani
February 16, 2021

The contribution of cerebral vascular neuropathology to mild stage of Alzheimer's dementia using the NACC database.

Current Alzheimer Research
Yue LiuNady Braidy
February 16, 2021
Open Access

Recent Consanguinity and Outbred Autozygosity Are Associated With Increased Risk of Late-Onset Alzheimer's Disease.

Frontiers in Genetics
Valerio NapolioniMichael D Greicius

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