Alzheimer's Disease: APP

Amyloid precursor protein (APP) proteolysis is critical for the development of Alzheimer's disease, a neurodegenerative disease associated with accumulation of amyloid plaques in the brain. Here is the latest research on APP and Alzheimer's disease.

October 19, 2021
Preprint
Open Access

Cryo-EM Structures of Amyloid-β 42 Filaments from Human Brain

BioRxiv : the Preprint Server for Biology
Y. ` YangM. Goedert
October 18, 2021
Preprint
Open Access

Deficiency of p38α-MAPK in myeloid cells ameliorates symptoms and pathology of APP-transgenic Alzheimer's disease mice

BioRxiv : the Preprint Server for Biology
Q. LuoYang Liu
October 18, 2021
Preprint
Open Access

Magnetic Resonance Imaging in Animal Models of Alzheimer’s Disease Amyloidosis

Preprints.org
Ruiqing Ni
October 17, 2021

Regional age-related atrophy after screening for preclinical alzheimer disease.

Neurobiology of Aging
Lauren N KoenigDominantly Inherited Alzheimer Network (DIAN)
October 17, 2021

Aggregation and structure of amyloid β-protein.

Neurochemistry International
Kenjiro Ono, Takahiro Watanabe-Nakayama
October 16, 2021
Preprint
Open Access

Amyloid-beta and tau pathologies are both necessary to induce novel stage-specific microglia subtypes during Alzheimer's disease progression.

BioRxiv : the Preprint Server for Biology
D. W. KimTong Li
October 16, 2021
Preprint
Open Access

Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimers Disease

BioRxiv : the Preprint Server for Biology
C. JuC. Justin Justin Lee
October 16, 2021

Artemether Attenuates Aβ25-35-Induced Cognitive Impairments by Downregulating Aβ, BACE1, mTOR and Tau Proteins.

Clinical Laboratory
Hong-Juan LiChuanhai Cao
October 16, 2021

Age, vascular disease, and Alzheimer's disease pathologies in amyloid negative elderly adults.

Alzheimer's Research & Therapy
Tengfei GuoAlzheimer’s Disease Neuroimaging Initiative
October 16, 2021

Neurotransmitter-stimulated neuron-derived sEVs have opposite effects on amyloid β-induced neuronal damage.

Journal of Nanobiotechnology
Yunxiao DouXueyuan Liu
October 16, 2021
Open Access

Tau fibril with membrane lipids: Insight from computational modeling and simulations.

PloS One
Prechiel A BarredoMannix P Balanay
October 15, 2021
Preprint
Open Access

Positron Emission Tomography in Animal Models of Alzheimer’s Disease Amyloidosis

Preprints.org
Ruiqing Ni
October 15, 2021
Comment / Editorial

Introduction to the Special Issue "The Brain-Gut Axis".

Cellular and Molecular Neurobiology
Yvette Taché, Juan M Saavedra
October 15, 2021
Review

[Neuroprotective treatment of tauopathies].

Der Nervenarzt
Gesine RespondekGünter U Höglinger
October 15, 2021
Review

[Current findings on the coincidence of cerebral amyloid angiopathy and Alzheimer's disease].

Der Nervenarzt
R HaußmannJ Linn
October 15, 2021
Open Access

Cognitive Dysfunction in Cats: Update on Neuropathological and Behavioural Changes Plus Clinical Management.

The Veterinary Record
Lorena Sordo, Danièlle A Gunn-Moore

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