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Alzheimer's Disease: APP

Alzheimer's Disease: APP diagram by Public Domain, Wikimedia
Public Domain, Wikimedia

Amyloid precursor protein proteolysis is critical for the development of Alzheimer's disease, a neurodegenerative disease associated with accumulation of amyloid plaques. Here is the latest research.

Top 20 most recent papers
Acta Neuropathologica

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

Acta NeuropathologicaJanuary 20, 2020
Sven J van der LeeHenne Holstege
6
Journal of Neurology, Neurosurgery, and Psychiatry

Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia

Journal of Neurology, Neurosurgery, and PsychiatryJanuary 16, 2020
Carolin HellerGENFI
25
1
bioRxiv

Stromal Amyloid β drives Neutrophil extracellular trap formation to augment tumour growth

bioRxivJanuary 11, 2020
Hafsa MunirJacqueline D Shields
12
Molecular Psychiatry

MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties

Molecular PsychiatryJanuary 17, 2020
Nipun ChopraDebomoy K Lahiri
9
1
Journal of Alzheimer's Disease : JAD

The GSM BPN-15606 as a Potential Candidate for Preventative Therapy in Alzheimer's Disease

Journal of Alzheimer's Disease : JADJanuary 21, 2020
Olga PrikhodkoSteven L Wagner
Human Brain Mapping

Contribution of CSF biomarkers to early-onset Alzheimer's disease and frontotemporal dementia neuroimaging signatures

Human Brain MappingJanuary 17, 2020
Neus FalgàsRaquel Sánchez-Valle
20
Annals of Neurology

Neuroinflammatory markers associate with cognitive decline after major surgery: findings of an explorative study

Annals of NeurologyJanuary 14, 2020
Mattias DanielsonLars I Eriksson
1
Biomarkers in Neuropsychiatry

Complement component 3 levels in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder

Biomarkers in NeuropsychiatryJanuary 17, 2020
Anilkumar PillaiNunzio Pomara
2
Environmental Health Perspectives

Fungicide Residues Exposure and β -amyloid Aggregation in a Mouse Model of Alzheimer's Disease

Environmental Health PerspectivesJanuary 16, 2020
Pierre-André LafonVéronique Perrier
1
1
1
Journal of the American Society for Mass Spectrometry

Chemometric Strategies for Sensitive Annotation and Validation of Anatomical Regions of Interest in Complex Imaging Mass Spectrometry Data

Journal of the American Society for Mass SpectrometryJanuary 17, 2020
Patrick M WehrliJörg Hanrieder
Cellular and Molecular Life Sciences : CMLS

Deciphering the neuroprotective and neurogenic potential of soluble amyloid precursor protein alpha (sAPPα)

Cellular and Molecular Life Sciences : CMLSJanuary 22, 2020
Nawab John Dar, Gordon W Glazner
Scientific Reports

Accelerated neuronal and synaptic maturation by BrainPhys medium increases Aβ secretion and alters Aβ peptide ratios from iPSC-derived cortical neurons

Scientific ReportsJanuary 19, 2020
Tugce Munise SatirPetra Bergström
2
BMC Public Health

Evaluation of smartphone APP-based case-management services among antiretroviral treatment-naïve HIV-positive men who have sex with men: a randomized controlled trial protocol

BMC Public HealthJanuary 22, 2020
Xiaoyan FanJing Gu
Sub-cellular Biochemistry

Structure and Function of the AAA+ ATPase p97, a Key Player in Protein Homeostasis

Sub-cellular BiochemistryJanuary 16, 2020
Petra HänzelmannHermann Schindelin
Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia

Different clinical and neuroimaging features of Japanese dementia siblings with a new N-terminal mutation (Val225Ala) of APP gene

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of AustralasiaJanuary 16, 2020
Yasuyuki OhtaKoji Abe
1
JAMA Neurology

Ambroxol for the Treatment of Patients With Parkinson Disease With and Without Glucocerebrosidase Gene Mutations: A Nonrandomized, Noncontrolled Trial

JAMA NeurologyJanuary 14, 2020
Stephen MullinAnthony H V Schapira
80
2
2
PloS One

Protein-protein interactions underlying the behavioral and psychological symptoms of dementia (BPSD) and Alzheimer's disease

PloS OneJanuary 18, 2020
Yimin MaoHongxin Dong
1
Parasites & Vectors

Distribution, genetic characteristics and public health implications of Triatoma rubrofasciata, the vector of Chagas disease in Guangxi, China

Parasites & VectorsJanuary 22, 2020
Yunliang ShiYichao Yang
Analytical Chemistry

Low-level fusion of FT-ICR MS data sets for the characterization of nitrogen and sulfur compounds in vacuum gas oils

Analytical ChemistryJanuary 15, 2020
Julie GuillemantLudovic Duponchel
1
bioRxiv

Modular and distinct PlexinA4/Farp2/Rac1 signaling controls dendrite morphogenesis

bioRxivJanuary 16, 2020
Victor DanelonTracy S. Tran
3

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