Alzheimer's Disease: APP

Amyloid precursor protein proteolysis is critical for the development of Alzheimer's disease, a neurodegenerative disease associated with accumulation of amyloid plaques. Here is the latest research.

September 13, 2020
Open Access

Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging

Nature Communications
Joseph FloresAndréa C LeBlanc
September 15, 2020

Axonal Conduction Velocity in CA1 Area of Hippocampus is Reduced in Mouse Models of Alzheimer's Disease

Journal of Alzheimer's Disease : JAD
Simon GelmanAfshin Ghavami
September 20, 2020
Review

Potential human transmission of amyloid β pathology: surveillance and risks

Lancet Neurology
Elsa LauwersBart De Strooper
September 20, 2020
Preprint

The regulatory function of the AAA4 ATPase domain of cytoplasmic dynein

BioRxiv : the Preprint Server for Biology
Arne GennerichL. Rao
September 15, 2020

The Economics and Effectiveness of Advanced Practice Providers are Decidedly Local Phenomena

Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine
Richard D Zane, Sean S Michael
September 17, 2020

Molecular imaging of Alzheimer's disease-related gamma-secretase in mice and nonhuman primates

The Journal of Experimental Medicine
Yulong XuCan Zhang
September 13, 2020
Open Access

Amyloid-β1-43 cerebrospinal fluid levels and the interpretation of APP, PSEN1 and PSEN2 mutations

Alzheimer's Research & Therapy
Federica PerroneBELNEU Consortium
September 15, 2020
Review
Open Access

The complex relationship between genotype, pathology and phenotype in familial dementia

Neurobiology of Disease
John B KwokGlenda M Halliday
September 19, 2020
Open Access

Is invasive mediastinal staging necessary in intermediate risk patients with negative PET/CT?

Journal of Thoracic Disease
Marc BoadaLaureano Molins
September 15, 2020
Open Access

The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer's disease

Acta Neuropathologica
Baayla D C BoonJeroen J M Hoozemans
September 15, 2020

Aluminum and Neurofibrillary Tangle Co-Localization in Familial Alzheimer's Disease and Related Neurological Disorders

Journal of Alzheimer's Disease : JAD
Matthew John MoldChristopher Exley
September 18, 2020
Review

A comprehensive review of monoamine oxidase inhibitors as Anti-Alzheimer's disease agents: A review

European Journal of Medicinal Chemistry
Shoaib Manzoor, Nasimul Hoda
September 13, 2020
Open Access

Increased blood BACE1 activity as a potential common pathogenic factor of vascular dementia and late onset Alzheimer's disease

Scientific Reports
Giovanni ZulianiCarlo Cervellati
September 19, 2020

Neurofilament light chain in the vitreous humor of the eye

Alzheimer's Research & Therapy
Manju L SubramanianThor D Stein

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