Alzheimer's Disease: Endosomes

The feed focuses on the role of dysfunctional endosomal trafficking in Alzheimer’s Disease and the potential for targeting the endosome as a therapeutic target.

September 17, 2020

Hippocampal blood-brain barrier permeability is related to the APOE4 mutation status of elderly individuals without dementia

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
Won-Jin MoonSeol-Heui Han
September 11, 2020

The phenotype associated with variants in TANGO2 may be explained by a dual role of the protein in ER-to-Golgi transport and at the mitochondria

Journal of Inherited Metabolic Disease
Miroslav P MilevMichael Sacher
September 17, 2020

Rapid hematoma growth triggers spreading depolarizations in experimental intracortical hemorrhage

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
Paul FischerCenk Ayata
August 29, 2020
Review
Open Access

Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases

International Journal of Molecular Sciences
Rose Ghemrawi, Mostafa Khair
September 1, 2020

Cross Talk between Mitochondria and Other Targets in Alzheimer's Disease

Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society for Environmental Toxicology and Cancer
Rehana KhatoonSuhel Parvez
September 10, 2020
Review
Open Access

The Other Side of Alzheimer's Disease: Influence of Metabolic Disorder Features for Novel Diagnostic Biomarkers

Journal of Personalized Medicine
Chiara ArgentatiSabata Martino
September 10, 2020
Review
Open Access

Biomarkers for Alzheimer's Disease Early Diagnosis

Journal of Personalized Medicine
Eva AusóGema Esquiva
September 3, 2020
Preprint
Open Access

Activated iPSC-microglia from C9orf72 ALS/FTD patients exhibit endosomal-lysosomal dysfunction

BioRxiv : the Preprint Server for Biology
I. LorenziniRita Sattler
September 17, 2020

Remote ischemic conditioning enhances oxygen supply to ischemic brain tissue in a mouse model of stroke: Role of elevated 2,3-biphosphoglycerate in erythrocytes

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
Lin WangXunming Ji
September 16, 2020

Regulation of blood-brain barrier integrity by microglia in health and disease: A therapeutic opportunity

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
Patrick T Ronaldson, Thomas P Davis
September 1, 2020
Open Access

The Alzheimer's disease-associated C99 fragment of APP regulates cellular cholesterol trafficking

The EMBO Journal
Jorge MontesinosEstela Area-Gomez
September 8, 2020
Review

Boosting the autophagy-lysosomal pathway by phytochemicals: A potential therapeutic strategy against Alzheimer's disease

IUBMB Life
Fahimeh NourbakhshAmirhossein Sahebkar
September 17, 2020

Subarachnoid hemorrhage leads to early and persistent functional connectivity and behavioral changes in mice

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
David Y ChungCenk Ayata
September 5, 2020

Amyloid beta regulates ER exit sites formation through O-GlcNAcylation triggered by disrupted calcium homeostasis

Biology of the Cell
Hyun Jin Cho, Inhee Mook-Jung
September 18, 2020

Melasolv induces melanosome autophagy to inhibit pigmentation in B16F1 cells

PloS One
Hyun Jun ParkDong-Hyung Cho
September 10, 2020
Open Access

Gut Metabolite TMAO Induces Synaptic Plasticity Deficits by Promoting Endoplasmic Reticulum Stress

Frontiers in Molecular Neuroscience
Manoj GovindarajuluRajesh H Amin

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