Alzheimer's Disease: Endosomes

Dysfunctional endosomal trafficking may be associated with Alzheimer’s disease (AD) pathology. Targeting the endosome may advance treatment options for AD. Here is the latest research on endosomes and AD.

February 26, 2021
Open Access

Phosphoinositides signaling modulates microglial actin remodeling and phagocytosis in Alzheimer's disease.

Cell Communication and Signaling : CCS
Smita Eknath Desale, Subashchandrabose Chinnathambi
February 23, 2021

Role of extracellular vesicles in neurodegenerative diseases.

Progress in Neurobiology
Yun XiaoXing Li
February 21, 2021
Open Access

Flexible and accurate substrate processing with distinct presenilin/γ-secretases in human cortical neurons.

Hirotaka WatanabeHideyuki Okano
February 15, 2021

Role of the endolysosomal pathway and exosome release in tau propagation.

Neurochemistry International
Minli Yan, Tingting Zheng
February 14, 2021
Open Access

Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome.

Science Advances
Pasquale D'AcunzoEfrat Levy
February 10, 2021
Open Access

Proteomic Comparison of Aged and OPTN E50K Retina in The Development of Normal Tension Glaucoma

Xin-Na LiuHuiping Yuan
February 10, 2021
Open Access

Stem cells Therapies in Alzheimer's disease: applications for disease modeling.

The Journal of Pharmacology and Experimental Therapeutics
Zizhen Si, Xidi Wang
February 7, 2021
Open Access

Endosome Dysregulation in Down Syndrome: A Potential Contributor to Alzheimer Disease Pathology.

Annals of Neurology
Alessia Filippone, Domenico Praticò
February 5, 2021

Dark-Side of Exosomes.

Advances in Experimental Medicine and Biology
Atilla Engin
February 4, 2021

MicroRNA-135a in ABCA1-labeled Exosome is a Serum Biomarker Candidate for Alzheimer's Disease.

Biomedical and Environmental Sciences : BES
Chen Geng LiuPei Chang Wang
February 3, 2021

The Retromer Complex: From Genesis to Revelations.

Trends in Biochemical Sciences
Matthew N J Seaman
February 3, 2021

Microglial remodeling of actin network by Tau oligomers, via G protein-coupled purinergic receptor, P2Y12R-driven chemotaxis.

Rashmi Das, Subashchandrabose Chinnathambi
January 29, 2021

New Insights into the Role of Ferritin in Iron Homeostasis and Neurodegenerative Diseases.

Molecular Neurobiology
Na ZhangHuamin Xu
January 28, 2021
Open Access

Lysosome Function and Dysfunction in Hereditary Spastic Paraplegias.

Brain Sciences
Daisy EdmisonSwetha Gowrishankar
January 26, 2021
Open Access

BAG3 regulation of Rab35 mediates the ESCRT/endolysosome pathway and tau clearance

BioRxiv : the Preprint Server for Biology
H. LinGail VW Johnson
January 18, 2021
Open Access

Clearance of intracellular tau protein from neuronal cells via VAMP8-induced secretion.

The Journal of Biological Chemistry
Julie PilliodNicole Leclerc

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