Alzheimer's Disease: Genes&Microglia (Preprints)

Genes and microglia are associated with the risk of developing and the progression of conditions such as Alzheimer's Disease (AD). Here are the latest preprints pertaining to this disease.

July 26, 2020
Preprint
Open Access

The AppNL-G-F mouse retina is a site for preclinical Alzheimer's disease diagnosis and research

BioRxiv : the Preprint Server for Biology
M. VandenabeeleLies De Groef
August 1, 2020
Preprint

Specific mutations in genes responsible for Alzheimer and for Duchenne Muscular Dystrophy introduced by Base editing and PRIME editing.

BioRxiv : the Preprint Server for Biology
J. RousseauJacques P Tremblay
July 14, 2020
Preprint
Open Access

Molecular and cellular pathology of monogenic Alzheimer's disease at single cell resolution

BioRxiv : the Preprint Server for Biology
F. MarinaroFrederick J Livesey
July 16, 2020
Preprint
Open Access

Systematic identification of modifiable risk factors and drug repurposing options for Alzheimer's disease: Mendelian randomization analyses

MedRxiv : the Preprint Server for Health Sciences
Chong WuH.-W. Deng
July 28, 2020
Preprint
Open Access

Systemic inflammation causes microglial dysfunction with a mixed AD-like pathology.

BioRxiv : the Preprint Server for Biology
P. BathiniLavinia Alberi
July 16, 2020
Preprint
Open Access

Apolipoprotein E isoform-specific phase transitions in the retinal pigment epithelium drive disease phenotypes in age-related macular degeneration

BioRxiv : the Preprint Server for Biology
N. La CunzaAparna Lakkaraju
July 16, 2020
Preprint
Open Access

Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer's Disease Neuroimaging Initiative

MedRxiv : the Preprint Server for Health Sciences
T. K. KarikariH. Zetterberg
July 14, 2020
Preprint
Open Access

Time course of phosphorylated tau181 in blood across the Alzheimer's disease spectrum

MedRxiv : the Preprint Server for Health Sciences
A. MoscosoMichael Schoell
July 21, 2020
Preprint
Open Access

3D-Visualization of Amyloid-β Oligomer and Fibril Interactions with Lipid Membranes by Cryo-Electron Tomography

BioRxiv : the Preprint Server for Biology
Y. TianJohn H Viles
July 24, 2020
Preprint
Open Access

Plasma amyloid, phosphorylated tau, and neurofilament light for individualized risk prediction in mild cognitive impairment

MedRxiv : the Preprint Server for Health Sciences
N. C. CullenOskar Hansson
July 10, 2020
Preprint
Open Access

CircTulp4 functions in Alzheimer's disease pathogenesis by regulating its parental gene, Tulp4

BioRxiv : the Preprint Server for Biology
August 1, 2020
Preprint

Multiplexed fractionated proteomics reveals synaptic factors associated with cognitive resilience in Alzheimer's Disease

BioRxiv : the Preprint Server for Biology
Becky Catherine CarlyleS. E. Arnold
July 25, 2020
Preprint
Open Access

AD-linked R47H-TREM2 mutation induces disease-enhancing proinflammatory microglial states in mice and humans

BioRxiv : the Preprint Server for Biology
F. A. SayedLi Gan
July 25, 2020
Preprint
Open Access

Neurodegeneration induces a developmental RNA processing program by calpain-mediated MBNL2 degradation

BioRxiv : the Preprint Server for Biology
Guey-Shin WangGuey-Shin Wang
July 12, 2020
Preprint
Open Access

Genome-wide identification of novel long non-coding RNAs and their possible roles in hypoxic zebrafish brain

BioRxiv : the Preprint Server for Biology
July 16, 2020
Preprint
Open Access

Presenilin-deficient neurons and astrocytes display normal mitochondrial phenotypes

BioRxiv : the Preprint Server for Biology
S. ContinoPascal Kienlen-Campard
July 29, 2020
Preprint

Thermodynamics and kinetics of the amyloid-β peptide revealed by Markov state models based on MD data in agreement with experiment

BioRxiv : the Preprint Server for Biology
A. PaulBirgit Strodel
July 21, 2020
Preprint
Open Access

Recruitment of Older African Americans in Alzheimers Disease Clinical Trials Using A Community Based Research Approach

MedRxiv : the Preprint Server for Health Sciences
A. R. ShawE. D. Vidoni
July 13, 2020
Preprint
Open Access

Endosomal trafficking is required for glycosylation and normal maturation of the Alzheimer's-associated protein sorLA

BioRxiv : the Preprint Server for Biology
S. K. ChristensenOlav M Andersen
July 25, 2020
Preprint
Open Access

Mild cognitive impairment is associated with skeletal muscle mitochondrial deficits

MedRxiv : the Preprint Server for Health Sciences
Jill K MorrisJ. P. Thyfault

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