Alzheimer's Disease: Genes&Microglia

Genes and microglia are associated with the risk of developing and the progression of conditions such as Alzheimer's Disease (AD). Here are the latest discoveries pertaining to this disease.

September 17, 2020

Astrocyte remodeling in the beneficial effects of long-term voluntary exercise in Alzheimer's disease

Journal of Neuroinflammation
Irina BelayaKatja M Kanninen
September 15, 2020

Vitexin prevents Aβ proteotoxicity in transgenic Caenorhabditis elegans model of Alzheimer's disease by modulating unfolded protein response

Journal of Biochemical and Molecular Toxicology
Dicson Sheeja MalarKasi Pandima Devi
September 15, 2020

Nano-hesperetin enhances the functional recovery and endogenous remyelination of the optic pathway in focal demyelination model

Brain Research Bulletin
Saeideh BaradaranAkbar Hajizadeh Moghaddam
September 15, 2020

Tacr3/NK3R: Beyond Their Roles in Reproduction

ACS Chemical Neuroscience
Wen-Wen ZhangYu-Xia Chu
September 15, 2020

Neuronal Calcium Imaging, Excitability, and Plasticity Changes in the Aldh2-/- Mouse Model of Sporadic Alzheimer's Disease

Journal of Alzheimer's Disease : JAD
Adam O GhoweriOlivier Thibault
September 15, 2020
Open Access

Transcriptome Analyses in BV2 Microglial Cells Following Treatment With Amino-Terminal Fragments of Apolipoprotein E

Frontiers in Aging Neuroscience
Tanner B PollockTroy T Rohn
September 15, 2020

Traumatic Injury Reduces Amyloid Plaque Burden in the Transgenic 5xFAD Alzheimer's Mouse Spinal Cord

Journal of Alzheimer's Disease : JAD
Tak-Ho ChuPeter K Stys
September 15, 2020
Review
Open Access

The complex relationship between genotype, pathology and phenotype in familial dementia

Neurobiology of Disease
John B KwokGlenda M Halliday
September 15, 2020

Data-Driven Modeling of Knowledge Assemblies in Understanding Comorbidity Between Type 2 Diabetes Mellitus and Alzheimer's Disease

Journal of Alzheimer's Disease : JAD
Reagon KarkiMartin Hofmann-Apitius
September 16, 2020

Regulation of blood-brain barrier integrity by microglia in health and disease: A therapeutic opportunity

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
Patrick T Ronaldson, Thomas P Davis
September 15, 2020
Open Access

The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer's disease

Acta Neuropathologica
Baayla D C BoonJeroen J M Hoozemans
September 15, 2020

Novel Amyloid-beta pathology C. elegans model reveals distinct neurons as seeds of pathogenicity

Progress in Neurobiology
Christian GallreinJanine Kirstein
September 15, 2020

Aluminum and Neurofibrillary Tangle Co-Localization in Familial Alzheimer's Disease and Related Neurological Disorders

Journal of Alzheimer's Disease : JAD
Matthew John MoldChristopher Exley
September 16, 2020
Review

Mechanisms of NLRP3 Inflammasome Activation: Its Role in the Treatment of Alzheimer's Disease

Neurochemical Research
Yidan ZhangGuofeng Yang
September 15, 2020

Positive association of a Sirt1 variant and parameters of oxidative stress on Alzheimer's disease

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Daniela CamporezFlavia de Paula
September 16, 2020

Amyloid, tau and risk of Alzheimer's disease: a Mendelian randomization study

European Journal of Epidemiology
Chris Ho Ching YeungC Mary Schooling
September 15, 2020

Corneal Nerve and Brain Imaging in Mild Cognitive Impairment and Dementia

Journal of Alzheimer's Disease : JAD
Eiman Al-JanahiRayaz A Malik

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