Alzheimer's Disease: Microglia

Microglia are a type of glial cell found throughout the brain and spinal cord. Microglia have been found to be associated with Alzheimer's disease development and progression. Here are the latest discoveries pertaining to Alzheimer's disease and microglia.

February 24, 2021

Pinpointing Brain TREM2 Levels in Two Mouse Models of Alzheimer's Disease.

Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging
Silvio R MeierStina Syvänen
February 23, 2021

Role of Hypoxia Inducible Factor-1α in Alzheimer's Disease.

Journal of Alzheimer's Disease : JAD
Yang-Yang WangZhi-You Cai
February 23, 2021
Open Access

Alzheimer's Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia.

Frontiers in Immunology
Marvin ReichMarkus Britschgi
February 23, 2021
Review

Neuroinflammation in Alzheimer's disease and beneficial action of luteolin.

BioFactors
Alejandro DelgadoTheoharis C Theoharides
February 23, 2021

Early intervention attenuates synaptic plasticity impairment and neuroinflammation in 5xFAD mice.

Journal of Psychiatric Research
Kai LiZhuo Yang
February 22, 2021
Preprint
Open Access

Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy

BioRxiv : the Preprint Server for Biology
C. WangLi Gan
February 21, 2021
Review

Microglial phagocytosis of neurons in neurodegeneration, and its regulation.

Journal of Neurochemistry
Claire A ButlerGuy C Brown
February 21, 2021

Distinct amyloid-β and tau-associated microglia profiles in Alzheimer's disease.

Acta Neuropathologica
Emma GerritsErik W G M Boddeke
February 20, 2021
Review
Open Access

The roles of astrocytic phagocytosis in maintaining homeostasis of brains.

Journal of Pharmacological Sciences
Se Young Lee, Won-Suk Chung
February 20, 2021
Open Access

Reversible Tau Phosphorylation Induced by Synthetic Torpor in the Spinal Cord of the Rat.

Frontiers in Neuroanatomy
Timna HitrecMarco Luppi
February 20, 2021

Retina and Brain Display Early and Differential Molecular and Cellular Changes in the 3xTg-AD Mouse Model of Alzheimer's Disease.

Molecular Neurobiology
Ana Catarina Rodrigues-NevesAntónio Francisco Ambrósio
February 20, 2021

White matter aging drives microglial diversity.

Neuron
Shima SafaiyanMikael Simons
February 19, 2021
Open Access

Zinc status alters Alzheimer's disease progression through NLRP3-dependent inflammation.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Jack Rivers-AutyCatherine B Lawrence
February 19, 2021

APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function.

Science Translational Medicine
Monica XiongDavid M Holtzman
February 19, 2021
Open Access

Iron loading is a prominent feature of activated microglia in Alzheimer's disease patients.

Acta Neuropathologica Communications
Boyd KenkhuisLouise van der Weerd
February 19, 2021

CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer's disease.

Alzheimer's Research & Therapy
Simone M CrivelliPilar Martinez-Martinez
February 16, 2021
Review
Open Access

The Role of Microglia in Glioblastoma.

Frontiers in Oncology
Noelia Geribaldi-DoldánElkin Navarro Quiroz

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