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Alzheimer's Disease: Genetics

Alzheimer's Disease: Genetics diagram by undefined

Alzheimer's disease is a chronic neurodegenerative disease. Discover genetic and epigenetic aspects of Alzheimer’s disease, including genetic markers and genomic structural variations here.

Top 20 most recent papers
Science

Brain cell type-specific enhancer-promoter interactome maps and disease risk association

ScienceNovember 14, 2019
Alexi NottChristopher K. Glass
77
6
Scientific Reports

Genome Wide Meta-Analysis identifies common genetic signatures shared by heart function and Alzheimer's disease

Scientific ReportsNovember 13, 2019
Maria Eugenia SaezAgustin Ruiz
Scientific Reports

In vitro study of interaction of 17β-hydroxysteroid dehydrogenase type 10 and cyclophilin D and its potential implications for Alzheimer's disease

Scientific ReportsNovember 13, 2019
Erika HemmerováJirí Homola
Acta Neuropathologica Communications

Alzheimer's disease tau is a prominent pathology in LRRK2 Parkinson's disease

Acta Neuropathologica CommunicationsNovember 16, 2019
Michael X HendersonVirginia M Y- Lee
Scientific Reports

Human mitochondrial DNA lineages in Iron-Age Fennoscandia suggest incipient admixture and eastern introduction of farming-related maternal ancestry

Scientific ReportsNovember 15, 2019
Sanni ÖverstiPäivi Onkamo
44
8
Genome Biology

NanoSatellite: accurate characterization of expanded tandem repeat length and sequence through whole genome long-read sequencing on PromethION

Genome BiologyNovember 14, 2019
Arne De RoeckKristel Sleegers
25
Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics

Vildagliptin Attenuates Huntington's Disease through Activation of GLP-1 Receptor/PI3K/Akt/BDNF Pathway in 3-Nitropropionic Acid Rat Model

Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeuticsNovember 14, 2019
Noha H SayedAhmed S Kamel
3
Annals of Neurology

Lipid lowering and Alzheimer's disease risk: a Mendelian randomization study

Annals of NeurologyNovember 12, 2019
Dylan M. WilliamsAroon Dinesh Hingorani
13
2
Science Advances

Low-complexity domain of U1-70K modulates phase separation and aggregation through distinctive basic-acidic motifs

Science AdvancesNovember 1, 2019
Song XueShi-Zhong Luo
Neurobiology of Aging

Linking APOE-ε4, blood-brain barrier dysfunction, and inflammation to Alzheimer's pathology

Neurobiology of AgingOctober 15, 2019
Joost M RiphagenHeidi I L Jacobs
Brain : a Journal of Neurology

Disrupted glycosylation of lipids and proteins is a cause of neurodegeneration

Brain : a Journal of NeurologyNovember 14, 2019
Tobias MollJohnathan Cooper-Knock
15
1
International Review of Neurobiology

Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease

International Review of NeurobiologyOctober 23, 2019
Jessica L HoffmanClyde W Hodge
Experimental Neurology

Inhibition of excessive kallikrein-8 improves neuroplasticity in Alzheimer's disease mouse model

Experimental NeurologyNovember 14, 2019
Yvonne MünsterArne Herring
International Immunopharmacology

LXW7 attenuates inflammation via suppressing Akt/nuclear factor kappa B and mitogen-activated protein kinases signaling pathways in lipopolysaccharide-stimulated BV2 microglial cells

International ImmunopharmacologyNovember 12, 2019
Sijia PengL P Yi
International Journal of Molecular Sciences

Excitatory Amino Acid Transporters in Physiology and Disorders of the Central Nervous System

International Journal of Molecular SciencesNovember 12, 2019
Anna R Malik, Thomas E. Willnow
3
Molecular Neurobiology

Alterations of Transcription of Genes Coding Anti-oxidative and Mitochondria-Related Proteins in Amyloid β Toxicity: Relevance to Alzheimer's Disease

Molecular NeurobiologyNovember 16, 2019
Magdalena CieslikJoanna Benigna Strosznajder
International Review of Neurobiology

Preface: Setting the stage for understanding alcohol effects in late aging: A special issue including both human and rodent studies

International Review of NeurobiologyJanuary 1, 2019
Terrence Deak, Lisa M Savage
Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association

Phytol loaded PLGA nanoparticles regulate the expression of Alzheimer's related genes and neuronal apoptosis against amyloid-β induced toxicity in Neuro-2a cells and transgenic Caenorhabditis elegans

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research AssociationNovember 14, 2019
Sethuraman SathyaKasi Pandima Devi
Annals of Clinical and Translational Neurology

Study partner-reported decline identifies cognitive decline and dementia risk

Annals of Clinical and Translational NeurologyNovember 13, 2019
Rachel L NoshenyAlzheimer’s Disease Neuroimaging Initiative investigators
1
GigaScience

Deep learning for clustering of multivariate clinical patient trajectories with missing values

GigaScienceNovember 1, 2019
Johann de JongHolger Fröhlichholger Fröhlich
4

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