Alzheimer's Disease: Microglia

Microglia are a type of glial cell found throughout the brain and spinal cord. Microglia have been found to be associated with Alzheimer's disease development and progression. Here are the latest discoveries pertaining to Alzheimer's disease and microglia.

June 20, 2021

Scaffolding protein Gab2 is involved in postnatal development and lipopolysaccharide-induced activation of microglia in the mouse brain.

Biochemical and Biophysical Research Communications
Jae Woong ByeonHyun-Seok Park
June 19, 2021

COVID-19-related neuropathology and microglial activation in elderly with and without dementia.

Brain Pathology
Tino Emanuele PoloniMauro Ceroni
June 18, 2021

Alzheimer's Disease Genetics: A Dampened Microglial Response?

The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry
Zena K Chatila, Elizabeth M Bradshaw
June 18, 2021
Open Access

CD22 Blockage Restores Age-Related Impairments of Microglia Surveillance Capacity.

Frontiers in Immunology
Vanessa AiresEva Harde
June 17, 2021
Open Access

Amyloid-beta, p-tau, and reactive microglia load are correlates of MRI cortical atrophy in Alzheimer's disease

BioRxiv : the Preprint Server for Biology
Irene FrigerioL. E. Jonkman
June 17, 2021

C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation.

Deepti LallRobert H Baloh
June 15, 2021

Innate immunity stimulation via CpG oligodeoxynucleotides ameliorates Alzheimer's disease pathology in aged squirrel monkeys.

Brain : a Journal of Neurology
Akash G PatelHenrieta Scholtzova
June 15, 2021
Open Access

Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo.

Life Science Alliance
Karen N McFarlandTodd E Golde
June 15, 2021
Open Access

Sorafenib Modulates the LPS- and Aβ-Induced Neuroinflammatory Response in Cells, Wild-Type Mice, and 5xFAD Mice.

Frontiers in Immunology
Jieun KimHyang-Sook Hoe
June 15, 2021
Open Access

Nanoparticles: A Hope for the Treatment of Inflammation in CNS.

Frontiers in Pharmacology
Feng-Dan ZhuAn-Guo Wu
June 15, 2021
Open Access

Role of P2X7 Receptors in Immune Responses During Neurodegeneration.

Frontiers in Cellular Neuroscience
Ágatha Oliveira-GiacomelliHenning Ulrich
June 15, 2021

TREM2 Deficiency Disrupts Network Oscillations Leading to Epileptic Activity and Aggravates Amyloid-β-Related Hippocampal Pathophysiology in Mice.

Journal of Alzheimer's Disease : JAD
Milan StoiljkovicMihály Hajós
June 14, 2021

Ficus deltoidea: Potential Inhibitor of Pro-Inflammatory Mediators in Lipopolysaccharide-Induced Activation of Microglial Cells.

Journal of Ethnopharmacology
Siti Zaidathul Iman ZolkifflyMuhammad Zulfadli Mehat
June 13, 2021

Design, synthesis, and biological evaluation of furosemide analogs as therapeutics for the proteopathy and immunopathy of Alzheimer's disease.

European Journal of Medicinal Chemistry
Zhiyu WangDonald F Weaver
June 12, 2021
Open Access

Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer's disease.

Journal of Neuroinflammation
Xiao-Ying SunRui-Tian Liu
June 12, 2021
Open Access

Microglial metabolism is a pivotal factor in sexual dimorphism in Alzheimer's disease.

Communications Biology
Marie-Victoire Guillot-SestierMarina A Lynch

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