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Alzheimer's Disease: MS4A

Alzheimer's Disease: MS4A diagram by Pleiotrope (Public Domain)
Pleiotrope (Public Domain)

Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.

Top 20 most recent papers
bioRxiv

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

bioRxivFebruary 26, 2017
Kuan-Lin HuangAlison M. Goate
21
3
Science Translational Medicine

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk

Science Translational MedicineAugust 14, 2019
Yuetiva DemingCarlos Cruchaga
204
98
1
83
bioRxiv

Integration of Alzheimer's disease genetics and myeloid genomics reveals novel disease risk mechanisms

bioRxivJuly 6, 2019
Gloriia NovikovaAlison M. Goate
30
11
1
Journal of Alzheimer's Disease : JAD

Alzheimer's Disease-Related Polymorphisms in Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus

Journal of Alzheimer's Disease : JADJanuary 1, 2017
Joel HuovinenVille Leinonen
3
19
Mammalian Genome : Official Journal of the International Mammalian Genome Society

Human hyper-IgE syndrome: singular or plural?

Mammalian Genome : Official Journal of the International Mammalian Genome SocietyAugust 9, 2018
Qian ZhangJean-Laurent Casanova
1
16
Allergy

The protective effect of cheese consumption at 18 months on allergic diseases in the first 6 years

AllergyOctober 29, 2018
Sophie NicklausPASTURE Study Group
27
1
18
bioRxiv

Alzheimer's Genetic Risk Score linked to Incident Mild Behavioral Impairment

bioRxivOctober 10, 2017
Shea J AndrewsMoyra Elizabeth Mortby
3
4
Annales de dermatologie et de vénéréologie

Physiopathologie de la dermatite atopique: Pathophysiology of atopic dermatits.

Annales de dermatologie et de vénéréologieJanuary 1, 2017
Sebastien Barbarot, Hélène Aubert
2
6
Journal of the American Academy of Dermatology

Association between atopic dermatitis and contact sensitization: A systematic review and meta-analysis

Journal of the American Academy of DermatologyApril 11, 2017
Carsten Robert HamannJacob Pontoppidan Thyssen
2
2
42
Aging Cell

CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease

Aging CellMay 31, 2019
Yi-Yi MaKathryn L. Lunetta
2
1
9
bioRxiv

The MS4A gene cluster is a key regulator of soluble TREM2 and Alzheimer disease risk

bioRxivJune 20, 2018
Yuetiva DemingCarlos Cruchaga
17
75
Dermatitis : Contact, Atopic, Occupational, Drug

Prevalence of Atopic Dermatitis and Pattern of Drug Therapy in Malaysian Children

Dermatitis : Contact, Atopic, Occupational, DrugMay 16, 2018
Yi-Yeong GohYik Ling Chew
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology

Dust mite induces multiple polar T cell axes in human skin

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical ImmunologyOctober 5, 2017
Khalid MalikEmma Guttman-Yassky
1
15
Alzheimer's & Dementia : the Journal of the Alzheimer's Association

Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials

Alzheimer's & Dementia : the Journal of the Alzheimer's AssociationMarch 28, 2017
Michael W. WeinerAlzheimer's Disease Neuroimaging Initiative
9
1
254
Neurobiology of Aging

Genome-wide association study identifies Alzheimer's risk variant in MS4A6A influencing cerebrospinal fluid sTREM2 levels

Neurobiology of AgingMay 21, 2019
Xiao-He HouJin-Tai Yu
1
1
6
Advances in Experimental Medicine and Biology

Introduction

Advances in Experimental Medicine and BiologyJanuary 1, 2017
Erica A FortsonMahima Bhayana
Evidence-based Complementary and Alternative Medicine : ECAM

Effects of Angelica gigas Nakai as an Anti-Inflammatory Agent in In Vitro and In Vivo Atopic Dermatitis Models

Evidence-based Complementary and Alternative Medicine : ECAMMarch 11, 2018
Seon OkDeok-Seon Ryu
2
1
6
Gastroenterology

MicroRNAs 15A and 16-1 Activate Signaling Pathways That Mediate Chemotaxis of Immune Regulatory B cells to Colorectal Tumors

GastroenterologyOctober 17, 2017
Rong-hua LiuChu Yiwei
1
1
21
Neurobiology of Aging

Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs

Neurobiology of AgingNovember 19, 2018
Yuriko KatsumataDavid W. Fardo
2
2
28
Nutrients

Dioscorea quinqueloba Ameliorates Oxazolone- and 2,4-Dinitrochlorobenzene-induced Atopic Dermatitis Symptoms in Murine Models

NutrientsDecember 5, 2017
Jonghwan JegalMin Hye Yang

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