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Alzheimer's Disease: MS4A

Alzheimer's Disease: MS4A diagram by Atthapon Raksthaput, Shutterstock
Atthapon Raksthaput, Shutterstock

Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.

Top 20 most recent papers
Progress in Neurobiology

The epigenetics of aging and neurodegeneration

Progress in NeurobiologyJune 15, 2015
Roy LardenoijeBart P F Rutten
7
1
418
PloS One

Current Developments in Dementia Risk Prediction Modelling: An Updated Systematic Review

PloS OneSeptember 4, 2015
Eugene Y H TangBlossom C M Stephan
14
1
121
Alzheimer's & Dementia : the Journal of the Alzheimer's Association

Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials

Alzheimer's & Dementia : the Journal of the Alzheimer's AssociationMarch 28, 2017
Michael W WeinerAlzheimer's Disease Neuroimaging Initiative
8
1
283
Current Opinion in Neurobiology

Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease

Current Opinion in NeurobiologyOctober 31, 2015
Claudio Villegas-LlerenaJennifer M Pocock
3
1
284
Science Translational Medicine

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk

Science Translational MedicineAugust 16, 2019
Yuetiva DemingCarlos Cruchaga
204
98
1
75
JAMA Neurology

Genomics of Alzheimer Disease: A Review

JAMA NeurologyMay 3, 2016
Roger N RosenbergWeiming Xia
68
12
191
Annals of Clinical and Translational Neurology

Alzheimer's loci: epigenetic associations and interaction with genetic factors

Annals of Clinical and Translational NeurologyJuly 1, 2015
Lori B ChibnikPhilip L De Jager
3
1
48
Molecular and Cellular Neurosciences

Alzheimer disease (AD) specific transcription, DNA methylation and splicing in twenty AD associated loci

Molecular and Cellular NeurosciencesMay 26, 2015
Crystal HumphriesJohn Gilbert
1
1
63
Neurobiology of Aging

Common variants in ABCA7 and MS4A6A are associated with cortical and hippocampal atrophy

Neurobiology of AgingMarch 1, 2016
Leslie M RamirezLiana G Apostolova
9
4
2
48
Alzheimer's & Dementia : the Journal of the Alzheimer's Association

Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease

Alzheimer's & Dementia : the Journal of the Alzheimer's AssociationSeptember 15, 2015
Brian W KunkleMargaret A Pericak-Vance
13
1
1
44
Neurobiology of Aging

ABCA7 p.G215S as potential protective factor for Alzheimer's disease

Neurobiology of AgingJune 13, 2016
Celeste SassiJohn Hardy
9
1
1
82
3
5
Oncotarget

MS4A6A genotypes are associated with the atrophy rates of Alzheimer's disease related brain structures

OncotargetJune 1, 2016
Jing MaAlzheimer's Disease Neuroimaging Initiative
1
1
16

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