Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

June 27, 2020

Shared genetic etiology underlying late-onset Alzheimer's disease and posttraumatic stress syndrome

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Michael W LutzOrnit Chiba-Falek
April 30, 2020
Open Access

Investigating APOE, APP-Aβ metabolism genes and Alzheimer's disease GWAS hits in brain small vessel ischemic disease

Scientific Reports
Sonja BlumenauCeleste Sassi
December 5, 2019
Open Access

Association of MS4A6A, CD33, and TREM2 gene polymorphisms with the late-onset Alzheimer's disease

BioImpacts : BI
Elham MehdizadehSasan Andalib
November 12, 2019
Open Access

Genome-Wide Association Studies for Cerebrospinal Fluid Soluble TREM2 in Alzheimer's Disease

Frontiers in Aging Neuroscience
Changan Liu, Jun Yu
August 16, 2019
Open Access

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk

Science Translational Medicine
Y. DemingCarlos Cruchaga
July 6, 2019
Preprint
Open Access

Integration of Alzheimer's disease genetics and myeloid genomics reveals novel disease risk mechanisms

BioRxiv : the Preprint Server for Biology
Gloriia NovikovaAlison Goate
March 25, 2019
Review
Open Access

Genetics of Alzheimer's Disease

Dementia and Neurocognitive Disorders
Jong Hun Kim
March 13, 2019
Open Access

Shared genes between Alzheimer's disease and ischemic stroke

CNS Neuroscience & Therapeutics
Chang-Juan WeiXiao-Feng Ma
February 11, 2019
Review
Open Access

Microglia in Alzheimer's Disease: Exploring How Genetics and Phenotype Influence Risk

Journal of Molecular Biology
Amanda McQuade, Mathew Blurton-Jones
November 19, 2018
Open Access

Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs

Neurobiology of Aging
Yuriko KatsumataDavid W Fardo
June 20, 2018
Preprint
Open Access

The MS4A gene cluster is a key regulator of soluble TREM2 and Alzheimer disease risk

BioRxiv : the Preprint Server for Biology
Y. DemingCarlos Cruchaga
February 6, 2018
Review

Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase

Reviews in the Neurosciences
Harikesh DubeyArunabha Ray
November 28, 2017
Open Access

A hypermorphic antioxidant response element is associated with increased MS4A6A expression and Alzheimer's disease

Redox Biology
Sarah E LacherMatthew Slattery
June 27, 2017
Open Access

Functional annotation of Alzheimer's disease associated loci revealed by GWASs

PloS One
Zengpeng HanQingyang Huang
May 23, 2017
Preprint
Open Access

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer’s disease

BioRxiv : the Preprint Server for Biology
K.-l. HuangA L
May 10, 2017

Validating GWAS Variants from Microglial Genes Implicated in Alzheimer's Disease

Journal of Molecular Neuroscience : MN
Lígia Ramos Dos SantosFlavia de Paula
May 10, 2017
Open Access

African American exome sequencing identifies potential risk variants at Alzheimer disease loci

Neurology. Genetics
Aurelie N'SongoNilüfer Ertekin-Taner

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