Alzheimer's Disease: RNA Sequencing

RNA sequencing studies have shed light on the genetic and molecular mechanisms related to the pathophysiology of Alzheimer's disease (AD). This feed follows papers using RNA sequencing technologies in Alzheimer's research.

October 23, 2021
Preprint
Open Access

Genotype-Phenotype Correlation of T Cell Subtypes Reveals Senescent and Cytotoxic Genes in Alzheimer's Disease

BioRxiv : the Preprint Server for Biology
D. DressmanWassim Elyaman
October 16, 2021
Preprint
Open Access

Amyloid-beta and tau pathologies are both necessary to induce novel stage-specific microglia subtypes during Alzheimer's disease progression.

BioRxiv : the Preprint Server for Biology
D. W. KimTong Li
October 13, 2021

Isoorientin Affects Markers of Alzheimer's Disease via Effects on the Oral and Gut Microbiota in APP/PS1 Mice.

The Journal of Nutrition
Zhongbao ZhangZhongyi Wu
October 8, 2021

A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene.

Brain : a Journal of Neurology
Naciye MagusaliDervis A Salih
October 7, 2021
Open Access

Microglia Mediate the Occurrence and Development of Alzheimer's Disease Through Ligand-Receptor Axis Communication.

Frontiers in Aging Neuroscience
Chongdong JianDonghua Zou
October 7, 2021

Human neocortical expansion involves glutamatergic neuron diversification.

Nature
Jim BergEd S Lein
October 4, 2021
Open Access

Cell type-specific potential pathogenic genes and functional pathways in Alzheimer's Disease.

BMC Neurology
Xiao-Lan Wang, Lianjian Li
September 30, 2021
Open Access

Transcriptome analyses reveal tau isoform-driven changes in transposable element and gene expression.

PloS One
Jennifer GrundmanRobert A Rissman
September 29, 2021
Open Access

Alternative Splicing Regulation of Low-Frequency Genetic Variants in Exon 2 of TREM2 in Alzheimer's Disease by Splicing-Based Aggregation.

International Journal of Molecular Sciences
Seonggyun HanYounghee Lee
September 23, 2021
Preprint
Open Access

Revisit the Cellular Transmission and Emerging Techniques in Proteinopathies

Preprints.org
JIngwen JiangQihui Wu
September 16, 2021
Open Access

Reduced TREM2 activation in microglia of patients with Alzheimer's disease.

FEBS Open Bio
Yuumi OkuzonoShuji Sato
September 12, 2021
Preprint
Open Access

Psychosis in Alzheimer's Disease is Associated with Excitatory Neuron Vulnerability and Post-Transcriptional Mechanisms Altering Synaptic Protein Levels

MedRxiv : the Preprint Server for Health Sciences
M. R. DeChellis-MarksJ. Kofler
September 7, 2021
Open Access

Oxidative Phosphorylation Is Dysregulated Within the Basocortical Circuit in a 6-month old Mouse Model of Down Syndrome and Alzheimer's Disease.

Frontiers in Aging Neuroscience
Melissa J AlldredStephen D Ginsberg
September 7, 2021
Open Access

APOΕ4 lowers energy expenditure in females and impairs glucose oxidation by increasing flux through aerobic glycolysis.

Molecular Neurodegeneration
Brandon C FarmerLance A Johnson

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