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Amyloid Beta Deposition & Degradation

Amyloid Beta Deposition & Degradation diagram by Designua, Shutterstock
Designua, Shutterstock

Amyloid beta is neurotoxic and a major component of plaques in Alzheimer’s disease. Accumulation induces neurotoxic effects including oxidative damage and mitochondrial dysfunction. Breakdown of amyloid is important to prevent the development of Alzheimer’s disease. Here is the latest research on amyloid beta deposition and degradation.

Top 20 most recent papers
The Journal of Cell Biology

Heparan sulfate is a clearance receptor for aberrant extracellular proteins

The Journal of Cell BiologyMarch 27, 2020
Eisuke ItakuraAkira Matsuura
59
13
4
The Journal of Pathology

Cisd2: A promising new target in Alzheimer's disease

The Journal of PathologyMarch 25, 2020
Nobili AnnalisaMarcello D'Amelio
5
1
Acta Neuropathologica Communications

Neuropathological correlates of parkinsonian disorders in a large Dutch autopsy series

Acta Neuropathologica CommunicationsMarch 29, 2020
H GeutW D J van de Berg
bioRxiv

Mechanisms of γ-Secretase Activation and Substrate Processing

bioRxivMarch 11, 2020
Apurba BhattaraiYinglong Miao
2
Journal of Biomolecular Structure & Dynamics

An In-Silico approach: Identification of PPAR-γ agonists from Seaweeds for the management of Alzheimer's Disease

Journal of Biomolecular Structure & DynamicsMarch 29, 2020
Satvik KothaHarisha R
Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry

Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer's Disease

Molecules : a Journal of Synthetic Chemistry and Natural Product ChemistryMarch 15, 2020
Md Sahab UddinLotfi Aleya
3
1
Clinical Science

Inflammation: major denominator of obesity, Type 2 diabetes and Alzheimer's disease-like pathology?

Clinical ScienceMarch 14, 2020
Miroslava KacířováLenka Maletínská
4
1
Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry

Chitosan Oligosaccharides Attenuate Amyloid Formation of hIAPP and Protect Pancreatic β-Cells from Cytotoxicity

Molecules : a Journal of Synthetic Chemistry and Natural Product ChemistryMarch 19, 2020
Qin-Yu MengXin-Zhi Lu

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