Antibody-Dependent Cell Cytotoxicity

Antibody-dependent cellular toxicity refers to the lysis of a target cell by a non-sensitized effector cell of the immune system as a result of antibodies binding to the target cell membrane and engaging the Fc receptors on the immune effector cells. Find the latest research on antibody-dependent cellular toxicity here.

April 14, 2021

Obinutuzumab in combination with chemotherapy enhances direct cell death in CD20-positive obinutuzumab-resistant non-Hodgkin lymphoma cells.

Molecular Cancer Therapeutics
Takaaki FujimuraYasushi Yoshimura
April 14, 2021
Open Access

The FCGR3A 158 V/V-genotype is associated with decreased survival of renal allografts with chronic active antibody-mediated rejection.

Scientific Reports
Nicolle LitjensMichiel Betjes
April 12, 2021

Potential targets identified in adenoid cystic carcinoma point out new directions for further research.

American Journal of Translational Research
Zhenan LiuTingting Yu
April 6, 2021
Open Access

Zinc Import Mediated by AdcABC is Critical for Colonization of the Dental Biofilm by Streptococcus mutans in an Animal Model.

Molecular Oral Microbiology
Tridib GangulyJosé A Lemos
April 5, 2021
Review
Open Access

Antibodies Targeting the Transferrin Receptor 1 (TfR1) as Direct Anti-cancer Agents.

Frontiers in Immunology
Pierre V CandelariaTracy R Daniels-Wells
April 5, 2021

Mogamulizumab-induced vitiligo in patients with Sézary syndrome: three cases.

European Journal of Dermatology : EJD
Abdullah S AlgarniAdèle De Masson
April 5, 2021

Surface modified multifaceted nanocarriers for oral non-conventional cancer therapy; synthesis and evaluation.

Materials Science & Engineering. C, Materials for Biological Applications
Fiza Ur RehmanSara Qaisar
April 2, 2021
Preprint
Open Access

Microglia complement signaling promotes neuronal elimination and normal brain functional connectivity

BioRxiv : the Preprint Server for Biology
S. DeivasigamaniCornelius Thilo Gross
April 2, 2021
Open Access

Antibody Afucosylation Augments CD16-Mediated Serial Killing and IFNγ Secretion by Human Natural Killer Cells.

Frontiers in Immunology
Alexandros KarampatzakisDaniel M Davis
April 1, 2021
Review
Open Access

A Plausible Role for Collectins in Skin Immune Homeostasis.

Frontiers in Immunology
Tian WangYumin Xia
March 30, 2021
Review
Open Access

Immune evasion by cancer stem cells.

Regenerative Therapy
Hiroyuki Tsuchiya, Goshi Shiota

Sign up to follow this feed and discover related papers.

Related Feeds

Antibodies: Agglutination

Antibody-mediated agglutination is the clumping of cells in the presence of antibody, which binds multiple cells together. This enhances the clearance of pathogens. Find the latest research on antibody-mediated agglutination here.

Antibodies: Complement Activation

The complement system can be activated by antigen-associated antibody. In the classical pathway of complement activation, C1q, C4b, and C3b are all able to bind to the Fc portion of IgG or IgM. Find the latest research on antibodies and complement activation here.

Antibody Development

Development of antibodies require integration of knowledge with respect to target antigen properties, antibody design criteria such as affinity, isotype selection, Fc domain engineering, and antibody cross-reactivity across species from the early stages of antibody development. Here is the latest research.


Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.

Antibody synthesis

Antibodies have various functions including neutralization of pathogens, tumor targeting, as well as its utility in biomedical research. Here is the latest research on antibody synthesis.

Antibody-Dependent Enhancement

Antibody-dependent enhancement of viral infection is the entry of virus into host cells mediated by antiviral antibodies interacting with Fc or complement receptors. This has been most extensively observed with the dengue virus. Find the latest research on antibody-dependent enhancement here.

Antigenic Modulation

Antigenic modulation occurs when an antibody cross-links antigens on a cell surface, causing the antigens to become internalized. This can lead to therapeutic failure of monoclonal antibodies as the expression of the antigen becomes decreased on target cells. Find the latest research on antigenic modulation here.

B cell Activation

B cell activation is initiated by the ligation of the B cell receptor with antigen and ultimately results in the production of protective antibodies against potentially pathogenic invaders. Here is the latest research.

B cell Differentiation

Depending on the signal received through the B cell receptor and other receptors, B cells differentiate into follicular or marginal zone B cells. Here is the latest research pertaining to this differentiation process.

B cell Tolerance

B cell tolerance is maintained through mechanisms that can reversibly or irreversibly silence autoreactive B lymphocytes. Here is the latest research.

© 2021 Meta ULC. All rights reserved
/feed-previews/antibody-dependent-cell-cytotoxicity/b7638cb0-0881-4f16-85a1-0c032049bdb1