Antibody-Dependent Enhancement

Antibody-dependent enhancement of viral infection is the entry of virus into host cells mediated by antiviral antibodies interacting with Fc or complement receptors. This has been most extensively observed with the dengue virus. Find the latest research on antibody-dependent enhancement here.

July 22, 2020
Open Access

SARS-CoV-2 S1 is superior to the RBD as a COVID-19 subunit vaccine antigen

Journal of Medical Virology
Yunfei WangCunbao Liu
September 5, 2020
Open Access

Convalescent plasma for pediatric patients with SARS-CoV-2-associated acute respiratory distress syndrome

Pediatric Blood & Cancer
Caroline DiorioDavid T Teachey
August 6, 2020
Open Access

Plasmapheresis, Anti-ACE2 and Anti-FcγRII Monoclonal Antibodies: A Possible Treatment for Severe Cases of COVID-19

Drug Design, Development and Therapy
Amin Sedokani, Sadegh Feizollahzadeh
September 3, 2020
Open Access

SARS-CoV-2 And Trojan Horse Phenomenon -Caveat In Vaccine Quest?

Scandinavian Journal of Immunology
Mehak SinghPankaj Adhicari
August 13, 2020
Open Access

The role of IgG Fc receptors in antibody-dependent enhancement

Nature Reviews. Immunology
Stylianos BournazosJeffrey V Ravetch
July 17, 2020
Open Access

IgG antibody seroconversion and the clinical progression of COVID-19 pneumonia: A retrospective, cohort study

MedRxiv : the Preprint Server for Health Sciences
Kazuyoshi KurashimaT. Yanagisawa
August 25, 2020
Open Access

Anti-viral potential of garlic (Allium sativum ) and it's organosulfur compounds: A systematic update of pre-clinical and clinical data

Trends in Food Science & Technology
Razina RoufSatyajit D Sarker
August 2, 2020

Zika Virus-Like Particle (VLP) vaccine displaying Envelope (E) protein CD loop antigen elicits protective and specific immune response in a murine model

Biochemical and Biophysical Research Communications
Velasco CimicaTimothy T Stedman
August 6, 2020
Open Access

Is there antibody-dependent enhancement in SARS Coronavirus 2?

Journal of Family Medicine and Primary Care
Rohit KumarNaveet Wig
July 25, 2020
Open Access

High neutralizing potency of swine glyco-humanized polyclonal antibodies against SARS-CoV-2

BioRxiv : the Preprint Server for Biology
Bernard VanhoveJ.-P. Soulillou
September 5, 2020
Open Access

A complement component C1q-mediated mechanism of antibody-dependent enhancement of Ebola virus infection

PLoS Neglected Tropical Diseases
Wakako FuruyamaAyato Takada
September 3, 2020
Open Access

COVID-19: respuesta inmune y perspectivas terapéuticas.

Revista peruana de medicina experimental y salud pública
Iván Lozada-Requena, César Núñez Ponce
August 8, 2020
Open Access

Zika virus-induced neuro-ocular pathology in immunocompetent mice correlates with anti-ganglioside autoantibodies

Human Vaccines & Immunotherapeutics
Jacob T BeaverIoanna Skountzou

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Antibodies: Agglutination

Antibody-mediated agglutination is the clumping of cells in the presence of antibody, which binds multiple cells together. This enhances the clearance of pathogens. Find the latest research on antibody-mediated agglutination here.

Antibodies: Complement Activation

The complement system can be activated by antigen-associated antibody. In the classical pathway of complement activation, C1q, C4b, and C3b are all able to bind to the Fc portion of IgG or IgM. Find the latest research on antibodies and complement activation here.

Antibody Development

Development of antibodies require integration of knowledge with respect to target antigen properties, antibody design criteria such as affinity, isotype selection, Fc domain engineering, and antibody cross-reactivity across species from the early stages of antibody development. Here is the latest research.

Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.

Antibody synthesis

Antibodies have various functions including neutralization of pathogens, tumor targeting, as well as its utility in biomedical research. Here is the latest research on antibody synthesis.

Antibody-Dependent Cell Cytotoxicity

Antibody-dependent cellular toxicity refers to the lysis of a target cell by a non-sensitized effector cell of the immune system as a result of antibodies binding to the target cell membrane and engaging the Fc receptors on the immune effector cells. Find the latest research on antibody-dependent cellular toxicity here.

Antigenic Modulation

Antigenic modulation occurs when an antibody cross-links antigens on a cell surface, causing the antigens to become internalized. This can lead to therapeutic failure of monoclonal antibodies as the expression of the antigen becomes decreased on target cells. Find the latest research on antigenic modulation here.

B cell Activation

B cell activation is initiated by the ligation of the B cell receptor with antigen and ultimately results in the production of protective antibodies against potentially pathogenic invaders. Here is the latest research.

B cell Differentiation

Depending on the signal received through the B cell receptor and other receptors, B cells differentiate into follicular or marginal zone B cells. Here is the latest research pertaining to this differentiation process.

B cell Tolerance

B cell tolerance is maintained through mechanisms that can reversibly or irreversibly silence autoreactive B lymphocytes. Here is the latest research.

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