Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.

December 18, 2020
Open Access

Machine Learning to Quantify In Situ Humoral Selection in Human Lupus Tubulointerstitial Inflammation

Frontiers in Immunology
Andrew J KinlochMarcus R Clark
November 17, 2020
Open Access

Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells

BioRxiv : the Preprint Server for Biology
Juhee PaeGabriel D Victora
October 30, 2020

The role of B7 family members in the generation of Ig

Journal of Leukocyte Biology
Ze Xiu XiaoSong Guo Zheng
January 13, 2021
Open Access

Modeling human adaptive immune responses with tonsil organoids

Nature Medicine
Lisa E WagarMark M Davis
November 10, 2020

Chemoenzymatic Synthesis of Campylobacter jejuni Lipo-oligosaccharide Core Domains to Examine Guillain-Barré Syndrome Serum Antibody Specificities

Journal of the American Chemical Society
Tiehai LiGeert-Jan Boons
December 26, 2020
Open Access

Single point mutations can potentially enhance infectivity of SARS-CoV-2 revealed by in silico affinity maturation and SPR assay

BioRxiv : the Preprint Server for Biology
T. XueTianyuan Wang
November 17, 2020

Immunofluorescent Staining of Adult Murine Paraffin-Embedded Skeletal Tissue

Methods in Molecular Biology
Neta Felsenthal, Elazar Zelzer
January 10, 2021

Association between human leukocyte antigens (hlas) and human neutrophil antigens (hnas) and autoimmune neutropenia of infancy in danish patients

Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
Kaspar René NielsenRudi Steffensen
December 17, 2020

A rapid paper-based blood typing method from droplet wicking

The Analyst
Michael J HertaegGil Garnier
December 4, 2020

Biological evaluation of new TEM1 targeting recombinant antibodies for radioimmunotherapy: in vitro, in vivo and in silico studies

European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V
Alice D'OnofrioAntónio Paulo
November 18, 2020
Open Access

Tfh Cells in Health and Immunity: Potential Targets for Systems Biology Approaches to Vaccination

International Journal of Molecular Sciences
Hannah LawC Mee Ling Munier
January 8, 2021
Open Access

Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases

The Journal of Biological Chemistry
Catherine A HurdDarerca Owen
January 17, 2021

Development and validation of a high-parameter mass cytometry workflow to decipher immunomodulatory changes in celiac disease

Cytometry. Part B, Clinical Cytometry
Jose EstevamGlennda Smithson
January 10, 2021

Chromatin Immunoprecipitation (ChIP) to Study DNA-Protein Interactions

Methods in Molecular Biology
Eliza C SmallAndrea L Johnstone
December 9, 2020
Open Access

Multi-faceted regulation of IgE production and humoral memory formation

Allergology International : Official Journal of the Japanese Society of Allergology
Kei Haniuda, Daisuke Kitamura
November 25, 2020
Open Access

Development of cyclic peptides with potent in vivo osteogenic activity through RaPID-based affinity maturation

Proceedings of the National Academy of Sciences of the United States of America
Nasir K BashiruddinHiroaki Suga

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