Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.

February 16, 2020

Structural Basis for a Convergent Immune Response against Ebola Virus

Cell Host & Microbe
Hadas Cohen-DvashiRon Diskin
March 30, 2020
Open Access

H and L Chain Affinity Maturation and/or Fab N -Glycosylation Influence Immunoreactivity toward Neutrophil Extracellular Trap Antigens in Rheumatoid Arthritis Synovial B Cell Clones

The Journal of Immunology : Official Journal of the American Association of Immunologists
Elisa CorsieroMichele Bombardieri
April 14, 2020

Site-Specific Antibody Conjugation Strategy to Functionalize Virus-Based Nanoparticles

Bioconjugate Chemistry
Jooneon ParkNicole F Steinmetz
April 19, 2020
Open Access

Developments and Applications of Functional Protein Microarrays

Molecular & Cellular Proteomics : MCP
Guan-Da SyuHeng Zhu
February 11, 2020
Open Access

Prompting Fab Yeast Surface Display Efficiency by ER Retention and Molecular Chaperon Co-expression

Frontiers in Bioengineering and Biotechnology
Meng MeiLi Yi
February 12, 2020
Open Access

Point Mutations in Retargeted gD Eliminate the Sensitivity of EGFR/EGFRvIII-Targeted HSV to Key Neutralizing Antibodies

Molecular Therapy. Methods & Clinical Development
Ceren TuzmenJoseph C Glorioso
May 22, 2020
PreprintOpen Access

Human Antibodies Targeting a Transporter Mediate Protection Against Tuberculosis

medRxiv
A. WatsonNatalia Freund
May 12, 2020

An immunoassay for the HIV drug metabolites Tenofovir and Tenofovir diphosphate

ACS Infectious Diseases
Derin SevenlerRebecca Sandlin
February 22, 2020

Nanobody affinity improvement: Directed evolution of the anti-ochratoxin A single domain antibody

International Journal of Biological Macromolecules
Xuerou WangXing Liu
March 13, 2020
Open Access

T-Cell Receptor Variable β Domains Rigidify During Affinity Maturation

Scientific Reports
Monica L Fernández-QuinteroKlaus R Liedl
February 16, 2020

Bioinformatics design and experimental validation of influenza A virus multi-epitopes that induce neutralizing antibodies

Archives of Virology
G Lizbeth Ramírez-SalinasJosé Correa-Basurto

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