Antigenic Modulation

Antigenic modulation occurs when an antibody cross-links antigens on a cell surface, causing the antigens to become internalized. This can lead to therapeutic failure of monoclonal antibodies as the expression of the antigen becomes decreased on target cells. Find the latest research on antigenic modulation here.

May 24, 2020

Cytomegalovirus inhibition of extrinsic apoptosis determines fitness and resistance to cytotoxic CD8 T cells

Proceedings of the National Academy of Sciences of the United States of America
M Zeeshan ChaudhryLuka Cicin-Sain
April 15, 2020

Mutations in foot and mouth disease virus types A and O isolated from vaccinated animals

Revue Scientifique Et Technique
D A AbdulrahmanH A Hussein
March 31, 2020

A computational bio-chemo-mechanical model of in vivo tissue-engineered vascular graft development

Integrative Biology : Quantitative Biosciences From Nano to Macro
Ramak KhosraviJay D Humphrey
May 20, 2020
Open Access

Targeting macrophage checkpoint inhibitor SIRPa for anticancer therapy

JCI Insight
Jie LiuJens-Peter Volkmer
April 14, 2020
ReviewOpen Access

Matrix Stiffness and Colorectal Cancer

OncoTargets and Therapy
Chongshun LiuFengbo Tan
April 23, 2020
PreprintOpen Access

Cancer cell elimination by cytotoxic T cell cooperation and additive damage

B. WeigelinPeter Friedl
April 17, 2020
ReviewOpen Access

Meningococcal factor H-binding protein as immune evasion factor and vaccine antigen

FEBS Letters
Silvia PrincipatoRino Rappuoli
May 20, 2020

Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma

Nature Neuroscience
Alexandra GarancherRobert J Wechsler-Reya
March 22, 2020

Ub to no good: How cytomegaloviruses exploit the ubiquitin proteasome system

Virus Research
Vu Thuy Khanh Le-Trilling, Mirko Trilling
March 22, 2020

Dendritic cell development in infection

Molecular Immunology
Kristin Bieber, Stella E Autenrieth
May 27, 2020

Immunofluorescent Localization of Proteins in Schistosoma mansoni

Methods in Molecular Biology
Rashika El Ridi, Hatem Tallima
March 27, 2020
Open Access

Inhibition of MICA and MICB Shedding Elicits NK-Cell-Mediated Immunity against Tumors Resistant to Cytotoxic T Cells

Cancer Immunology Research
Lucas Ferrari de AndradeKai W Wucherpfennig
May 21, 2020

CD8+ T-cell-mediated immunoediting influences genomic evolution and immune evasion in murine gliomas

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
Joshua Robert KaneAdam M Sonabend

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