Antipsychotic-induced weight gain (aiwg) is a common adverse effect of this treatment, particularly with second-generation antipsychotics, and it is a major health problem around the world. Here are the latest discoveries pertaining to AIWG.
The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.
Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here
Catatonia is a psychomotor symptom in which patients present with stupor, although catatonic excitement may also present at the other end of the spectrum. Catatonia has been historically associated with schizophrenia although it is also associated with other neuropsychiatric disorders. Find the latest research on catatonic schizophrenia here.
There is ongoing debate regarding the handling of comorbidity in psychiatric disorders, and determining whether the issue lies with the categorizations of diagnostic conventions or if there is an underlying pathology that links multiple diseases. Understanding how to give the proper diagnosis/diagnoses would allow for optimal management of the patient. Find the latest research on comorbidity in psychiatry here.
Psychiatric disorders are known to be multifaceted in their pathophysiology. Because epigenetic changes can be sensitive to the environment, inherited, and reversible, the study of epigenetics in psychiatric disease is a logical way to understand the natural history of the disease as well as to develop therapeutics. Find the latest research on epigenetics and psychiatry here.
G-protein-coupled receptors (GPCRs), the largest family of integral membrane proteins, participate in the regulation of many physiological functions and are the targets of approximately 30% of currently marketed drugs. Here is the latest research.
Glial cells within the brain, particularly astrocytes and microglia, support synaptic transmission and neuron-glial circuit through the secretion of signaling molecules. The network of communication between glial cells and neurons is highly complex yet organized. Here is the latest research on glia and synaptic circuits.