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Antisense Oligonucleotide - Therapies For ALS

Antisense Oligonucleotide - Therapies For ALS diagram by Vaccinationist, Wikimedia
Vaccinationist, Wikimedia

This feed focuses on antisense oligonucleotide therapies such as Inotersen, Nusinursen, and Patisiran, in neurodegenerative diseases including amyotrophic lateral sclerosis.

Top 20 most recent papers
Science

Antisense oligonucleotides for neurodegeneration

ScienceMarch 29, 2020
Blair R Leavitt, Sarah J Tabrizi
87
Wiley Interdisciplinary Reviews. RNA

The powerful world of antisense oligonucleotides: From bench to bedside

Wiley Interdisciplinary Reviews. RNAApril 2, 2020
Anaïs M QuemenerMarie-Dominique Galibert
5
Acta Neuropsychiatrica

Systematic review of gene expression studies in people with Lewy Body Dementia

Acta NeuropsychiatricaMarch 18, 2020
Anisa Chowdhury, Anto P Rajkumar
4
Nature Reviews. Neurology

Development of disease-modifying drugs for frontotemporal dementia spectrum disorders

Nature Reviews. NeurologyMarch 24, 2020
Francesco PanzaBruno P Imbimbo
25
1
Bioconjugate Chemistry

Chemical Synthesis and Biological Application of Modified Oligonucleotides

Bioconjugate ChemistryApril 2, 2020
Daniel A GlazierWeiping Tang
Yonsei Medical Journal

Nusinersen as a Therapeutic Agent for Spinal Muscular Atrophy

Yonsei Medical JournalApril 2, 2020
Qing Li
Journal of the American Chemical Society

Origins of the increased affinity of phosphorothioate-modified therapeutic nucleic acids for proteins

Journal of the American Chemical SocietyMarch 24, 2020
Malwina Hyjek-SkładanowskaMarcin Nowotny
American Journal of Respiratory Cell and Molecular Biology

Antisense Oligonucleotides Targeting Jagged 1 Reduce House Dust Mite-Induced Goblet Cell Metaplasia in the Adult Murine Lung

American Journal of Respiratory Cell and Molecular BiologyMarch 17, 2020
Michele CarrerTamar R Grossman
3
Nucleic Acid Therapeutics

Delivery of Antisense Oligonucleotides to the Cornea

Nucleic Acid TherapeuticsMarch 24, 2020
Viet Q ChauV Vinod Mootha

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