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Antisense Oligonucleotides: ND

Antisense Oligonucleotides: ND diagram by Robinson R, Wikimedia
Robinson R, Wikimedia

This feed focuses on antisense oligonucleotide therapies such as Inotersen, Nusinursen, and Patisiran, in neurodegenerative diseases including amyotrophic lateral sclerosis.

Top 20 most recent papers
Current Opinion in Lipidology

Familial combined hypolipidemia: angiopoietin-like protein-3 deficiency

Current Opinion in LipidologyFebruary 6, 2020
Marcello ArcaIlenia Minicocci
Annual Review of Genomics and Human Genetics

Twenty-Five Years of Spinal Muscular Atrophy Research: From Phenotype to Genotype to Therapy, and What Comes Next

Annual Review of Genomics and Human GeneticsFebruary 1, 2020
Brunhilde WirthNatalia Mendoza-Ferreira
Nature Neuroscience

A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis

Nature NeuroscienceFebruary 19, 2020
Caitlin M RodriguezPeter K Todd
67
7
1
Pharmaceutical Patent Analyst

Targeting factor XI(a) for anticoagulation therapy: a patent landscape

Pharmaceutical Patent AnalystFebruary 15, 2020
Rami A Al-Horani
bioRxiv

MaTAR25 LncRNA Regulates the Tensin1 Gene to Impact Breast Cancer Progression

bioRxivFebruary 3, 2020
Kung-Chi ChangDavid L Spector
6
Genes & Development

Recurrent SRSF2 mutations in MDS affect both splicing and NMD

Genes & DevelopmentFebruary 1, 2020
Mohammad Alinoor RahmanAdrian R Krainer
29
15
Journal of Cachexia, Sarcopenia and Muscle

Myostatin inhibition in combination with antisense oligonucleotide therapy improves outcomes in spinal muscular atrophy

Journal of Cachexia, Sarcopenia and MuscleFebruary 8, 2020
Haiyan ZhouFrancesco Muntoni
2
Indian Pediatrics

Antisense Oligonucleotides: A Unique Treatment Approach

Indian PediatricsFebruary 16, 2020
Abhinaya V Krishnan, Devendra Mishra
European Journal of Human Genetics : EJHG

Cryptic exon activation causes dystrophinopathy in two Chinese families

European Journal of Human Genetics : EJHGFebruary 13, 2020
Ming JinZhi-Qiang Wang
Nature Reviews. Neurology

Antisense oligonucleotide hope for childhood epilepsies

Nature Reviews. NeurologyFebruary 1, 2020
Ian Fyfe
Current Opinion in Chemical Biology

Progress toward the development of the small molecule equivalent of small interfering RNA

Current Opinion in Chemical BiologyFebruary 10, 2020
Matthew D DisneyJessica L Childs-Disney
Molecular Cell

Harnessing the Power of Proteolysis for Targeted Protein Inactivation

Molecular CellFebruary 1, 2020
Rati VermaRaymond J Deshaies
47
1

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