Antisense Oligonucleotides: ND

This feed focuses on antisense oligonucleotide therapies such as Inotersen, Nusinursen, and Patisiran, in neurodegenerative diseases including amyotrophic lateral sclerosis.

February 25, 2021

RLIP Depletion Induces Apoptosis Associated with Inhibition of JAK2/STAT3 Signaling in Melanoma Cells.

Sharad S SinghalRavi Salgia
February 25, 2021

Tailor-made oligonucleotide-loaded lipid-polymer nanosystems designed for bone gene therapy.

Drug Delivery and Translational Research
Patricia García-GarcíaAraceli Delgado
February 25, 2021

Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell.

Journal of the American Chemical Society
Laurent KnerrShalini Andersson
February 24, 2021

A Novel Peptide-Equipped Exosomes Platform for Delivery of Antisense Oligonucleotides.

ACS Applied Materials & Interfaces
Huiying XuBang-Ce Ye
February 24, 2021
Open Access

Aortic valvular stenosis - novel therapeutic strategies.

European Journal of Clinical Investigation
Joanna NatorskaAnetta Undas
February 22, 2021
Open Access

Highly sensitive screening of antisense sequences for different types of DMD mutations in patients' urine-derived cells.

Journal of the Neurological Sciences
Hotake TakizawaYoshitsugu Aoki
February 23, 2021
Case Report
Open Access

Successful weaning from mechanical ventilation in a patient with SMA type 1 treated with nusinersen.

Annals of Clinical and Translational Neurology
Jiwon LeeJeehun Lee
February 23, 2021

A transformable gold nanocluster aggregate-based synergistic strategy for potentiated radiation/gene cancer therapy.

Journal of Materials Chemistry. B, Materials for Biology and Medicine
Chun WuYong-Qiang Li
February 23, 2021

A Decade of FDA-Approved Drugs (2010-2019): Trends and Future Directions.

Journal of Medicinal Chemistry
Dean G Brown, Heike J Wobst
February 21, 2021
Open Access

Systemic delivery of antagomirs during blood brain barrier disruption is disease-modifying in experimental epilepsy.

Molecular Therapy : the Journal of the American Society of Gene Therapy
Cristina R ReschkeDavid C Henshall
February 20, 2021
Open Access

Novel Experimental Agents for the Treatment of Hypercholesterolemia.

Journal of Experimental Pharmacology
Ivan Pećin, Željko Reiner
February 20, 2021

Antisense-Induced Downregulation of Clock Genes in the Shell Region of the Nucleus Accumbens Reduces Binge Drinking in Mice.

Alcoholism, Clinical and Experimental Research
Rishi SharmaMahesh Thakkar
February 18, 2021

Multi-omics analysis to visualize the dynamic roles of defense genes in the response of tea plants to gray blight.

The Plant Journal : for Cell and Molecular Biology
Shuangshuang WangChaoling Wei
February 18, 2021

Delivery of Nusinersen Through an Ommaya Reservoir in Spinal Muscular Atrophy.

Journal of Clinical Neuromuscular Disease
Susan T IannacconeDale Swift

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