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ApoE Phenotypes

ApoE Phenotypes diagram by Swaminathan et al, Wikimedia
Swaminathan et al, Wikimedia

Apolipoprotein E (APOE) is a protein involved in fat metabolism and associated with the pathogenesis of Alzheimer's disease and cardiovascular disease. Here is the latest research on APOE phenotypes.

Top 20 most recent papers
Journal of Alzheimer's Disease : JAD

Effect Modifiers of TDP-43 Associated Hippocampal Atrophy Rates in Patients with Alzheimer's Disease Neuropathological Changes

Journal of Alzheimer's Disease : JADJanuary 14, 2020
Marina BuciucKeith A Josephs
1
PloS One

First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation

PloS OneJanuary 17, 2020
Gregory BrubakerJonathan D Smith
Environmental Health : a Global Access Science Source

Associations of Perfluoroalkyl substances with blood lipids and Apolipoproteins in lipoprotein subspecies: the POUNDS-lost study

Environmental Health : a Global Access Science SourceJanuary 15, 2020
Gang LiuQi Sun
1
bioRxiv

Apolipoprotein E4 disrupts the neuroprotective action of sortilin in neuronal lipid metabolism and endocannabinoid signaling

bioRxivJanuary 14, 2020
Antonino AsaroThomas Willnow
14
PloS One

Selection of memory clinic patients for CSF biomarker assessment can be restricted to a quarter of cases by using computerized decision support, without compromising diagnostic accuracy

PloS OneJanuary 16, 2020
Hanneke F M Rhodius-MeesterWiesje M van der Flier
2
bioRxiv

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

bioRxivJanuary 15, 2020
Man Ying WongWenjie Luo
4
Human Brain Mapping

Longitudinal trajectory of Amyloid-related hippocampal subfield atrophy in nondemented elderly

Human Brain MappingJanuary 17, 2020
Liwen ZhangAlzheimer's Disease Neuroimaging Initiative
4
Journal of Alzheimer's Disease : JAD

CCL23: A Chemokine Associated with Progression from Mild Cognitive Impairment to Alzheimer's Disease

Journal of Alzheimer's Disease : JADJanuary 21, 2020
Júlia FauraJoan Montaner
1
Journal of Clinical Lipidology

Triglycerides, hypertension, and smoking predict cardiovascular disease in dysbetalipoproteinemia

Journal of Clinical LipidologyJanuary 22, 2020
Martine PaquetteAlexis Baass
EMBO Molecular Medicine

Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology

EMBO Molecular MedicineJanuary 18, 2020
Annerieke SierksmaMark Fiers
26
Molecular Neurobiology

Reduced Influence of apoE on Aβ43 Aggregation and Reduced Vascular Aβ43 Toxicity as Compared with Aβ40 and Aβ42

Molecular NeurobiologyJanuary 19, 2020
Lieke JäkelMarcel M Verbeek
3
Neuroscience

Erratum to 'Altered Temporal Organization of Brief Spontaneous Brain Activities in Patients with Alzheimer's Disease' [Neuroscience 425C (2020) 1-11

NeuroscienceJanuary 15, 2020
Xiangyu MaAlzheimer's Disease Neuroimaging Initiative
1
1
Neuroscience

The differential effect of treadmill exercise intensity on hippocampal soluble aβ and lipid metabolism in APP/PS1 mice

NeuroscienceJanuary 20, 2020
B ZengH L Liu
2
Acta Neuropathologica

Picalm reduction exacerbates tau pathology in a murine tauopathy model

Acta NeuropathologicaJanuary 12, 2020
Kunie AndoJean-Pierre Brion
8
1
International Journal of Clinical and Experimental Pathology

Genistein alleviates atherosclerosis in apolipoprotein E-deficient mice by interrupting the OX40/OX40L pathway

International Journal of Clinical and Experimental PathologyJanuary 15, 2020
Jiannan WeiLiming Zhang
1
Chemistry & Biodiversity

Integrating Network Pharmacology and Components analysis Study on Anti-atherosclerotic Mechanisms of Total Flavonoids of Engelhardia Roxburghiana Wall. Leaves in Mice

Chemistry & BiodiversityJanuary 17, 2020
Jie WeiGuining Wei
Heart and Vessels

Lipocalin-2 exerts pro-atherosclerotic effects as evidenced by in vitro and in vivo experiments

Heart and VesselsJanuary 22, 2020
Koichiro ShibataTakuya Watanabe
Disease Models & Mechanisms

Cell-specific and athero-protective roles for RIPK3 in a murine model of atherosclerosis

Disease Models & MechanismsJanuary 19, 2020
Sarah ColijnCourtney T Griffin
1
Pharmaceutical Medicine

Current Landscape of Late-Phase Clinical Trials for Alzheimer's Disease: Comparing Regional Variation Between Subjects in Japan and North America

Pharmaceutical MedicineJanuary 15, 2020
Masashi KikuchiKatsura Tsukamoto
1
Food Research International

Changes in whey proteome with lactation stage and parity in dairy cows using a label-free proteomics approach

Food Research InternationalJanuary 21, 2020
Yongxin YangJiaqi Wang
2
2

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