Feed Preview

Astrocytes & Amyloid

Astrocytes & Amyloid diagram by Pics56, Wikimedia
Pics56, Wikimedia

The relationship between astrocytes and amyloid has been suggested in some neurological diseases such as Alzheimer’s disease. Neuronal damage stimulates the activation of reactive astrocytes, which may the source of amyloid that forms in Alzheimer’s. Here is the latest research on astrocytes and amyloid.

Top 20 most recent papers

Inactive variants of death receptor p75NTR reduce Alzheimer's neuropathology by interfering with APP internalization

bioRxivJanuary 10, 2020
Carlos F. IbanezKazuhiro Tanaka
Trends in Molecular Medicine

Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus

Trends in Molecular MedicineJanuary 22, 2020
Benjamin C ReevesKristopher T Kahle

Neuropathology of a remarkable case of memory impairment informs human memory

NeuropsychologiaJanuary 24, 2020
A F GaoR S Rosenbaum
Acta Neuropathologica Communications

Epidemiological pathology of Aβ deposition in the ageing brain in CFAS: addition of multiple Aβ-derived measures does not improve dementia assessment using logistic regression and machine learning approaches

Acta Neuropathologica CommunicationsDecember 7, 2019
Stephen B WhartonCognitive Function and Ageing Neuropathology Study Group
Brain Research Bulletin

Multiple inflammatory profiles of microglia and altered neuroimages in APP/PS1 transgenic AD mice

Brain Research BulletinJanuary 14, 2020
Lifen LiuQionglan Yuan
European Journal of Medicinal Chemistry

Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents

European Journal of Medicinal ChemistryDecember 15, 2019
Gui-Xiang YangLei Ma

Strategy to enhance transgene expression in proximity of amyloid plaques in a mouse model of Alzheimer's disease

TheranosticsNovember 23, 2019
Danielle Weber-AdrianIsabelle Aubert

Melanoma-secreted Amyloid Beta Supresses Neuroinflammation and Promotes Brain Metastasis

bioRxivNovember 26, 2019
Kevin KleffmanEva Hernando
Journal of Alzheimer's Disease : JAD

Association of Cerebrospinal Fluid S100B Protein with Core Biomarkers and Cognitive Deficits in Prodromal and Mild Alzheimer's Disease

Journal of Alzheimer's Disease : JADNovember 7, 2019
Julia ChristlChristian Lange-Asschenfeldt
International Neurourology Journal

Cellular and Molecular Mediators of Neuroinflammation in Alzheimer Disease

International Neurourology JournalDecember 5, 2019
Seung-Hoon Yang
Acta Neuropathologica Communications

Aldehyde dehydrogenase 2 activity and aldehydic load contribute to neuroinflammation and Alzheimer's disease related pathology

Acta Neuropathologica CommunicationsDecember 13, 2019
Amit U JoshiDaria Mochly-Rosen
Neurochemistry International

Iron chelators inhibit amyloid-β-induced production of lipocalin 2 in cultured astrocytes

Neurochemistry InternationalNovember 25, 2019
Doortje W DekensPetrus J W Naudé
European Journal of Pharmacology

Geniposidic acid ameliorates spatial learning and memory deficits and alleviates neuroinflammation via inhibiting HMGB-1 and downregulating TLR4/2 signaling pathway in APP/PS1 mice

European Journal of PharmacologyDecember 16, 2019
Zhangjiuzhi ZhouYanli Hu

Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice

AgingDecember 21, 2019
Chen DilingWu Qingping
Toxicology Letters

Environmental lead exposure aggravates the progression of Alzheimer's disease in mice by targeting on blood brain barrier

Toxicology LettersNovember 16, 2019
Sai WuYun He
Tissue Engineering. Part a

Human Stem Cell-derived Aggregates of Forebrain Astroglia Respond to Amyloid Beta Oligomers

Tissue Engineering. Part aNovember 8, 2019
Kyle GriffinYan Li
International Neurourology Journal

Methyl-CpG Binding Protein 2 in Alzheimer Dementia

International Neurourology JournalDecember 5, 2019
Baeksun KimHeh-In Im
ACS Chemical Neuroscience

WBQ5187, a Multitarget Directed Agent, Ameliorates Cognitive Impairment in a Transgenic Mouse Model of Alzheimer's Disease and Modulates Cerebral β-Amyloid, Gliosis, cAMP Levels, and Neurodegeneration

ACS Chemical NeuroscienceNovember 8, 2019
Zhiren WangXiaoping Yang
Frontiers in Pharmacology

Family C G-Protein-Coupled Receptors in Alzheimer's Disease and Therapeutic Implications

Frontiers in PharmacologyNovember 14, 2019
Ilaria Dal PràAnna Chiarini
Parkinson's Disease

Analysis of the Relationship between Type II Diabetes Mellitus and Parkinson's Disease: A Systematic Review

Parkinson's DiseaseDecember 25, 2019
Fauze Camargo MalufAlzira Alves de Siqueira Carvalho

See more papers from this feed

Related Feeds


Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS here.


ALS shares with a considerable proportion of FTD cases the same neuropathological substrate, namely, inclusions of abnormally phosphorylated protein tdp-43 (ptdp-43). Here are the latest discoveries pertaining to ptdp-43 and these diseases.

ALS - Pathogenic Mechanisms

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating pathogenic mechanisms that underlie this genetically heterogeneous disorder.

ALS - Phenotypes

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating phenotypes associated with this genetically heterogeneous disorder.

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

ALS: Prions

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion-like mechanisms are associated with the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). Here are the latest discoveries pertaining to this disease.

ALS: Stress Granules

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. TDP-43 is an ALS-linked protein that is known to regulate splicing and storage of specific mRNAs into stress granules, which have been implicated in formation of ALS protein aggregates. Here is the latest research.

ALS: Therapies

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS therapies here.

ALS: Transposon de-silencing

Transposon silencing is a form of transcriptional gene silencing. These gene silencing mechanisms are impaired in Amyotrophic lateral sclerosis (ALS). Here are the latest discoveries pertaining to transposon silencing and this disease.

Age-related Dementia

Age-related dementia (Alzheimer's disease) results from the destructive impact of the pulse on cerebral vasculature. Evidence is reviewed that the neuropathology of the dementia is caused by the breakdown of small cerebral vessels (silent microbleeds), that the microbleeds result from pulse-induced damage to the cerebral vessels, and that pulse becomes increasingly destructive with age, because of the age-related stiffening of the aorta and great arteries, which causes an increase in the intensity of the pressure pulse. Discover the latest research on age-related dementia here.

© 2020 Meta ULC. All rights reserved