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Astrocytes & Amyloid

Astrocytes & Amyloid diagram by Pics56, Wikimedia
Pics56, Wikimedia

The relationship between astrocytes and amyloid has been suggested in some neurological diseases such as Alzheimer’s disease. Neuronal damage stimulates the activation of reactive astrocytes, which may the source of amyloid that forms in Alzheimer’s. Here is the latest research on astrocytes and amyloid.

Top 20 most recent papers
bioRxiv

Inactive variants of death receptor p75NTR reduce Alzheimer's neuropathology by interfering with APP internalization

bioRxivJanuary 10, 2020
Carlos F. IbanezKazuhiro Tanaka
2
Trends in Molecular Medicine

Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus

Trends in Molecular MedicineJanuary 22, 2020
Benjamin C ReevesKristopher T Kahle
9
Neuropsychologia

Neuropathology of a remarkable case of memory impairment informs human memory

NeuropsychologiaJanuary 24, 2020
A F GaoR S Rosenbaum
Acta Neuropathologica Communications

Epidemiological pathology of Aβ deposition in the ageing brain in CFAS: addition of multiple Aβ-derived measures does not improve dementia assessment using logistic regression and machine learning approaches

Acta Neuropathologica CommunicationsDecember 7, 2019
Stephen B WhartonCognitive Function and Ageing Neuropathology Study Group
2
1
Brain Research Bulletin

Multiple inflammatory profiles of microglia and altered neuroimages in APP/PS1 transgenic AD mice

Brain Research BulletinJanuary 14, 2020
Lifen LiuQionglan Yuan
2
1
European Journal of Medicinal Chemistry

Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents

European Journal of Medicinal ChemistryDecember 15, 2019
Gui-Xiang YangLei Ma
1
1
Theranostics

Strategy to enhance transgene expression in proximity of amyloid plaques in a mouse model of Alzheimer's disease

TheranosticsNovember 23, 2019
Danielle Weber-AdrianIsabelle Aubert
2
1
bioRxiv

Melanoma-secreted Amyloid Beta Supresses Neuroinflammation and Promotes Brain Metastasis

bioRxivNovember 26, 2019
Kevin KleffmanEva Hernando
18
Journal of Alzheimer's Disease : JAD

Association of Cerebrospinal Fluid S100B Protein with Core Biomarkers and Cognitive Deficits in Prodromal and Mild Alzheimer's Disease

Journal of Alzheimer's Disease : JADNovember 7, 2019
Julia ChristlChristian Lange-Asschenfeldt
1
1
International Neurourology Journal

Cellular and Molecular Mediators of Neuroinflammation in Alzheimer Disease

International Neurourology JournalDecember 5, 2019
Seung-Hoon Yang
1
Acta Neuropathologica Communications

Aldehyde dehydrogenase 2 activity and aldehydic load contribute to neuroinflammation and Alzheimer's disease related pathology

Acta Neuropathologica CommunicationsDecember 13, 2019
Amit U JoshiDaria Mochly-Rosen
25
4
1
Neurochemistry International

Iron chelators inhibit amyloid-β-induced production of lipocalin 2 in cultured astrocytes

Neurochemistry InternationalNovember 25, 2019
Doortje W DekensPetrus J W Naudé
6
1
European Journal of Pharmacology

Geniposidic acid ameliorates spatial learning and memory deficits and alleviates neuroinflammation via inhibiting HMGB-1 and downregulating TLR4/2 signaling pathway in APP/PS1 mice

European Journal of PharmacologyDecember 16, 2019
Zhangjiuzhi ZhouYanli Hu
3
Aging

Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice

AgingDecember 21, 2019
Chen DilingWu Qingping
4
1
Toxicology Letters

Environmental lead exposure aggravates the progression of Alzheimer's disease in mice by targeting on blood brain barrier

Toxicology LettersNovember 16, 2019
Sai WuYun He
1
Tissue Engineering. Part a

Human Stem Cell-derived Aggregates of Forebrain Astroglia Respond to Amyloid Beta Oligomers

Tissue Engineering. Part aNovember 8, 2019
Kyle GriffinYan Li
3
4
International Neurourology Journal

Methyl-CpG Binding Protein 2 in Alzheimer Dementia

International Neurourology JournalDecember 5, 2019
Baeksun KimHeh-In Im
1
1
ACS Chemical Neuroscience

WBQ5187, a Multitarget Directed Agent, Ameliorates Cognitive Impairment in a Transgenic Mouse Model of Alzheimer's Disease and Modulates Cerebral β-Amyloid, Gliosis, cAMP Levels, and Neurodegeneration

ACS Chemical NeuroscienceNovember 8, 2019
Zhiren WangXiaoping Yang
3
Frontiers in Pharmacology

Family C G-Protein-Coupled Receptors in Alzheimer's Disease and Therapeutic Implications

Frontiers in PharmacologyNovember 14, 2019
Ilaria Dal PràAnna Chiarini
12
1
4
Parkinson's Disease

Analysis of the Relationship between Type II Diabetes Mellitus and Parkinson's Disease: A Systematic Review

Parkinson's DiseaseDecember 25, 2019
Fauze Camargo MalufAlzira Alves de Siqueira Carvalho
4
1

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